A new study provides a framework for measuring the impact of community engagement programs in advancing translational science. The researchers developed a road map that incorporates evidence-based strategies for implementing effective CE programs.
Researchers at the University of Tsukuba have created light-induced topological states in zinc arsenide, exhibiting unusual behavior where electrical currents flow along the surface. This work explores the possibility of creating topological semimetals and manifesting new physical properties by light control.
A study by University of Barcelona researchers has identified TIMP-1 as a key player in the progression of non-small cell lung cancer, a subtype of adenocarcinoma. Elevated levels of TIMP-1 from fibroblasts can cause increased tumor proliferation and invasion when interacting with CD63 receptors on cancer cells.
A UConn study found that Connecticut's notification system for substance-ex exposed infants has connected over half of identified cases with community supports and services. The system, which uses de-identified data, has shown promise in reducing disparities in testing and reporting, but there is still room for improvement.
Researchers at Washington State University found that eco-friendly hotel certifications do not lead to financial benefits for hotels. However, displaying comparable pricing information and informing consumers about green certification can boost future sales. The study suggests that the tourism industry needs sustainable practices to re...
Researchers found that mandatory breath testing among commercial drivers had no significant effect on the number of alcohol-related collisions between 2011 and 2020. The trend was similar to non-commercial drivers, suggesting that other measures may be needed to reduce drunk driving.
A recent study found that nearly half of men and one in five women engaged in 'bulk and cut' cycles, connected with a greater desire for muscularity. The study also linked this dietary method to symptoms of eating disorders and muscle dysmorphia among participants.
Engineers at Rice University have discovered a way to manipulate light at the nanoscale that surpasses the traditional Moss rule for optical materials. The researchers found that iron pyrite has a high refractive index, making it suitable for applications such as virtual reality and 3D displays.
A team of researchers identified the clubroot pathogen in Mexico, a crucial discovery for the country's broccoli production and global supply. The study used a detection methodology developed during Covid-19, allowing for accurate identification and potential future outbreaks.
A study by Regenstrief Institute and Indiana University School of Medicine found that music can reduce the likelihood of critically ill, mechanically ventilated older adults developing delirium. Music exposure was associated with improved post-ICU brain health and reduced risk of death.
Researchers found that antifouling membranes, which resist contaminant accumulation, cost less over their lifetimes than cheaper alternatives. This leads to reduced operating expenses for municipal wastewater facilities and desalination plants.
Researchers from The University of Tokyo created a geometric technique to characterize self-replication processes, shedding light on living systems' environmental conditions. This work aims to improve our understanding of biological reproduction and the theoretical limits governing chemistry and biology.
Researchers identify two distinct types of obesity with physiological and molecular differences that may impact health, disease, and treatment response. The study reveals new insights into the link between insulin and obesity, as well as the role of epigenetics in shaping individual body types.
Researchers at Cleveland Clinic link HSD3B1 genotype to higher risk of type 2 endometrial cancer, which is more aggressive and has lower survival rates than type 1. The study builds on previous associations with breast and prostate cancer, suggesting the gene could serve as a biomarker for certain subtypes.
A new poll reveals that nearly half of people over 50 experience joint pain, and many turn to prescription-based treatments despite potential health risks. The poll's authors stress the need for healthcare providers to discuss medication interactions and non-drug options with patients.
Researchers have developed a three-step process to treat phosphoric acid plant wastewater, recovering clean water and phosphate while reducing the volume of wastewater by 90%. The circular process uses selective electrodialysis, reverse osmosis, and neutralization, making it a promising solution for industries worldwide.
A new project aims to develop resources and AI models to assess biomedical publications for citation accuracy and integrity, benefiting researchers, journals, and policymakers. The project, led by Associate Professors Halil Kilicoglu and Jodi Schneider, received a $300,000 grant from the US Department of Health and Human Services.
A budget impact analysis found that catheter-based TAVR is an affordable and effective strategy for treating aortic stenosis patients, with lower total costs compared to surgical SAVR. The study showed that the upfront cost of TAVR is partially offset by reduced healthcare resources, making it a more efficient option.
People with diabetes face higher risk of hospitalization during extreme heat events due to dehydration and blood glucose imbalance. Research reveals a link between extreme heat and emergency hospitalizations for hypo- and hyperglycemia-related conditions.
A new study by Newcastle University found that individual corals have varying levels of heat tolerance, with some able to withstand double the heat stress required to induce bleaching and mortality. This variability suggests capacity for adaptation if some of the toughest corals can survive marine heatwaves.
A new study suggests that neoadjuvant novel hormonal therapy followed by prostatectomy can reduce the risk of recurrent and progressive cancer in high-risk prostate cancer patients. After treatment with NHAs, patients were more likely to have negative margins after surgery and fewer cases of biochemical recurrence.
Researchers at MUSC found that extracting and isolating Treg cells and transplanting them back into the same system successfully treats osteogenesis imperfecta for a year. The treatment results in stronger bones, increased osteoblast numbers, and decreased osteoclast numbers.
A study on wild geladas reveals maternal effects on the gut microbiome both before and after weaning, influencing infant development and health. The research found that infants of first-time moms had slower gut microbiota development, potentially leading to a developmental disadvantage.
A new study finds that neon goby parents help their offspring develop by pushing them out the door at the right time. Offspring hatched by parents are larger and more developed than those that hatch on their own, suggesting a complex parenting behavior. This discovery highlights the surprising complexities of fish parenting behavior.
Researchers identified a new mechanism by which SARS-CoV-2 induces inflammatory responses in COVID-19 patient lungs, leading to 'cytokine storm' and lasting tissue damage. The discovery highlights the role of plasmacytoid dendritic cells in triggering this response.
A new study suggests that canopy leaves in forests cannot cool themselves below the surrounding air temperature, leading to reduced forest carbon cycling and increased mortality risk. The research challenges a prevailing theory on leaf thermoregulation, highlighting the impact of climate warming on forests.
Scientists have developed a new chip that can transfer different optical states to switch light flows using supersymmetry. The approach enables broadband continuous transformation of light spatial characteristics, opening up avenues for advanced photonic functionalities.
A study published in Injury Prevention found that adolescents who experienced a concussion in the past 12 months were 25% more likely to be in poor academic standing. This association was stronger with a history of repeated concussions, and varied by race/ethnicity.
A new study by University of California, Berkeley researchers found that participating in Mission Innovation and intensifying technology competition from China are the strongest drivers of funding for clean energy RD&D. Despite growing public investment, the pace of transformation is not fast enough to facilitate rapid decarbonization.
Researchers will investigate racial and ethnic disparities in healthcare services for autistic children in New Jersey. The study aims to understand the social determinants of these disparities and promote health equity among children on the spectrum.
A new study from Aarhus University highlights the imbalance in AMD research using young male mice, despite the disease affecting the elderly. The review of 380 scientific articles emphasizes the need for better reporting and guidelines to improve animal testing quality.
A new study found that reports of elder abuse increased, particularly in cases of physical and emotional abuse, during the COVID-19 pandemic. Financial abuse remained the most common type, but higher rates of emotional and physical abuse were reported during the pandemic.
A recent study by Hee-Soon Juon PhD found that the obesity paradox in lung cancer diagnosis does not hold true for African Americans. While obesity is associated with lower rates of lung cancer diagnosis in the general population, this relationship was not statistically significant among African Americans.
West Virginia University and NASA are teaming up to provide hands-on STEM experiences for middle and high school students through the Plant the Moon Challenge project. The six-state consortium aims to increase diversity in science, engineering, technology, and math education by supporting teachers and students in underserved communities.
Researchers used Neuropixels probes to measure the activity of synaptically connected retinal and midbrain neurons, revealing a mosaic-like neural connection. The study provides new insights into visual processing and strengthens our understanding of blindsight.
Researchers at Case Western Reserve University have identified the structure of protein fibrils linked to a hereditary form of human prion disease, revealing the mechanism for interspecies transmission. The study suggests that disease transmission between species can be predicted based on structural information.
In southern Sydney, cockatoos have developed a unique behavior of opening garbage bins to eat food waste. Humans have responded by using various inventive methods to secure the bins, sparking an 'arms race' between the two species.
A study from UC San Diego finds increased depression, anxiety, and perceived stress in Latina mothers, particularly those in border cities, due to reduced coping resources. The researchers attribute these findings to the increasing hostility of the political climate towards Latinx Americans.
Industrial mining is responsible for more than half of tropical deforestation globally, with Indonesia accounting for 58.2% of the deforestation directly caused by mining activities. The study highlights the need for stronger measures to protect tropical forests from economic activities like mining. For Indonesia, Brazil and Ghana, tro...
A study by University of Cambridge and University of California, Berkeley finds that competition with China drove significant increases in clean energy investment between 2000 and 2018. The share of RD&D funding for clean technologies grew from 46% to 63%, while fossil fuel funding remained relatively unchanged.
A cross-sectional study of over 25,000 adults found that approximately 70% of identified adrenal tumors were nonfunctioning, regardless of participant's age. The prevalence of adrenal tumors increased with age, from 0.2% in young adults to 3.2% in older adults.
Restoring relatively narrow strips of riverfront forests could substantially improve regional water quality and carbon storage in Costa Rica. The analysis shows that such buffers tend to be most beneficial in steep, erosion-prone, and intensively fertilized landscapes.
Research by Tohoku University scientists found that contextual fear conditioning alters genes associated with the synapse in microglia, indicating a new mechanism linking microglia and neuronal activity related to fear conditioning. This non-immune communication may play a key role in fear memory consolidation and extinction.
A new study by Martin-Luther-University Halle-Wittenberg found that using only students in experiments can lead to biased results, as their decisions differ from those of other population groups. The study compared agricultural science students to farmers and found differences in risk-taking, patience, trust, and generosity.
Long-term opioid use after lung cancer surgery is associated with a 40% heightened death risk within two years, according to research. The study found that male sex, older age, and chemotherapy treatment are among the factors linked to long-term opioid use.
A study found that oral anticoagulants, such as apixaban, may be more effective than standard home heparin injections in preventing blood clots after urologic cancer surgery. The medication had significantly lower rates of compliance events and major complications compared to enoxaparin.
Researchers developed a label-free SERS method to detect the cysteine residues of the SARS-CoV-2 spike protein subunit, allowing consistent detection in human blood plasma, mucus, and saliva samples. This technique holds potential for diagnosing SARS-CoV-2 and other viral infections in remote areas.
Bladder cancer researchers discovered a subset of CD8 T cells that adapts to tumor evasion strategies, offering a strategy to reduce tumor cells' ability to fight them off. The study also identified potential ways to make immunotherapy more effective against this deadly cancer by targeting the HLA-E/NKG2A axis.
Realizing net-zero food systems necessitates the adoption of new technologies and diet shifts to reduce global greenhouse gas emissions. The goal is to achieve a net-zero emission global food system by 2050, with a roadmap outlining milestones for implementation by 2030 and 2040.
Researchers at La Jolla Institute for Immunology discovered how Zika virus forces dendritic cells to churn out lipid molecules, allowing the virus to build copies of itself. This study provides a major step forward in developing antiviral therapies against multiple flavivirus infections.
Researchers found that those severely impacted by Hurricane Harvey were four times more likely to experience income loss and five times more likely to suffer severe anxiety during the pandemic. The study highlights the cumulative effect of economic stress and mental health impacts on an individual's well-being.
A new study published in leading journals found that achieving 10,000 steps a day can lower the risk of dementia, heart disease, cancer, and death. However, a faster stepping pace showed even greater health benefits, making walking faster a crucial factor for overall health.
A study found that eating at night increased depression-like mood levels among participants, while daytime eating reduced these levels. The researchers suggest that meal timing could be a novel strategy to minimize mood vulnerability in individuals with circadian misalignment.
A study by University of Pittsburgh researchers found that older adults with consistent daily routines are happier, less depressed, and have better cognitive function. Participants who rose early, stayed active throughout the day, and followed a regular routine performed better on cognitive tests than those with disrupted patterns.
A new study from Harvard University identifies the genes and genetic sequences that orchestrate the formation of the human pelvis during pregnancy. The research shows that key pelvic features form around 6- to 8-week mark, including a curved and basin-like shape.
Research from Washington University in St. Louis found that children exposed to cannabis in the womb continue to exhibit increased signs of psychiatric conditions, including depression and anxiety. The study, which followed over 10,500 children, revealed no significant changes in psychiatric condition rates as they aged into adolescence.
A new rodent study found that low doses of alcohol can trigger epigenomic and transcriptomic changes in the brain, creating an epigenetic pathway for addiction. The research suggests that even small quantities of alcohol can prime the brain for addiction, regardless of sex or quantity.
Researchers at Osaka Metropolitan University developed a cold perfusion method to isolate hepatic stellate cells (HSCs) from both murine and human fatty liver-associated tumors with high yield and purity. This breakthrough could provide new tools for investigating the role of HSCs in NASH-associated liver cancer progression.
Researchers at Imperial College London discovered a 'silent' mutation in bacteria that helps them evade antibiotics. The mutation alters the structure of an mRNA intermediate, preventing ribosomes from producing protein, and has arisen independently several times globally.
Researchers at Michigan State University discovered that increased carbon dioxide levels decrease phosphorus levels in plants, making them less nutritious. The team found that plants avoid overloading their chloroplasts with phosphorus as an adaptive response to elevated CO2 levels.
A study led by Arizona State University Professor Gabriel Shaibi found that a community-based program combining education and exercise significantly improves the health of Latino children at risk for diabetes. The program, which included 117 families from around the Valley, provided culturally focused lessons on healthy eating and phys...
The study found that colloidal membranes transition from flat disc-like shapes to saddle-like shapes as the fraction of short rods increases. The saddles then merge into more complex structures like catenoids and four-noids, exhibiting properties similar to biological membranes.
A phase 2 study found that combining nivolumab and ipilimumab showed a high response rate with durable results for patients with advanced Merkel cell carcinoma. The addition of stereotactic body radiation therapy did not improve efficacy in this dual checkpoint inhibitor therapy.
A new combination immunotherapy regimen shows remarkable activity in metastatic colorectal cancer patients without liver metastases, achieving a response rate of 40% and median overall survival exceeding 20 months. The study's findings confirm the importance of the tumor microenvironment in shaping the response to immunotherapy.
A study from Linköping University shows that individuals with type 1 diabetes should keep their mean long-term sugar level below 53 mmol/mol (7.0%) to avoid serious damage. The risk of eye- and kidney complications increases as the level increases.
A University of Houston engineer has developed a sprayable ice-shedding material that is 100 times stronger than any others. The new durable coating material controls interfacial fractures and can accelerate crack formation and growth.
A systematic review and meta-analysis found that training programs for community supervision improve outcomes for both probation officers and their clients. The programs enhance the selection of topics to discuss and intervention strategies during client contact sessions.
In a Phase I/II trial, selpercatinib demonstrated a 44% objective response rate across multiple tumor types, including pancreatic and colorectal cancers. The study found responses regardless of cancer type or prior treatment history, confirming RET fusions as a tissue-agnostic target.
Scientists defined the structure of a substrate-bound iron enzyme and found it uses cations to drive desaturation during catalysis. The work could lead to the creation of valuable molecules like vinyl isonitriles with antibiotic properties.
Researchers found that vaccine companies, such as Moderna and Pfizer, experience significant price movements when one company performs well or poorly. Sinopharm is found to be the most affected by market volatility, while AstraZeneca has the greatest influence on Moderna's stock price.
Researchers found that lettuce takes up nanoplastics from soil and transfers them into the food chain, with particles detected in insects and fish. The study highlights potential health risks to herbivores and humans due to tiny plastic particles in soil.
In an international clinical trial, 63.3% of patients with stage II-IV cutaneous squamous cell carcinoma saw their tumors nearly or completely disappear when treated with immunotherapy before surgery. The anti-PD1 therapy cemiplimab was well-tolerated and met its primary endpoint with a pathologic complete response rate of 50.6%.
Researchers found that mTOR inhibition is crucial for p53-mediated tumor suppression, delaying cancer and increasing lifespan. In the absence of mTOR inhibition, cancer-promoting senescent cells drive tumor growth.
A new study suggests that massive volcanic eruptions were the primary cause of mass extinctions, including the one that wiped out the dinosaurs. The research found a strong temporal connection between flood basalt eruptions and significant climatic events.
A new study by NC State University found that total formulation impacts surface sanitizer efficacy against norovirus, with only alcohol-based products showing significant reduction. Additionally, paper towels used to clean up messes can be a source of cross-contamination.
The AI model, trained with end-to-end and multi-task manners, achieves best drivability in a standard simulation environment, outperforming recent models. It extracts useful information from a single RGBD camera and uses sensor fusion techniques to enhance performance.
Researchers found that dark matter halos in ultra-diffuse galaxies have lower concentrations than expected, raising questions about their formation and evolution. The study's surprising results indicate these galaxies may be younger and contain more gas than normal galaxies.
Researchers used a computer model to identify potential candidates for treating ASD, including loperamide, which has shown promise in restoring social behaviors in genetically engineered mice. The study suggests that repurposing existing drugs like loperamide could provide a new treatment option for core autism symptoms.
A study found that resiliency and family support play a crucial role in helping Hispanic breast cancer survivors manage lymphedema. Adaptations such as modifying work tasks and seeking support from family members enable survivors to maintain their quality of life.
A new study challenges traditional stereotypes by revealing that subordinate men are most likely to engage in social sexual behavior for personal gain. The research found that these men use unwanted flirtation and harassment to appear more powerful and masculine in the workplace.
Scientists have developed a thin device that can produce complex webs of entangled photons, enabling new information processing schemes and advanced encryption methods. The device uses a metasurface to control the phenomenon of quantum entanglement, paving the way for more compact and powerful computing and sensing technologies.
Researchers have successfully inserted nanotubes into bacteria, allowing for the creation of
A new software application predicts the likelihood that a case of dilated cardiomyopathy has a genetic mutation. The Madrid Genotype Score identifies patients most likely to have inherited the disease, facilitating genetic screening and tailored treatment adjustments.
Researchers from Johns Hopkins Medicine and Dana Farber Cancer Institute found that irisin reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice. Irisin also speeds up the transport and degradation of alpha synuclein via fluid-filled sacs called lysosomes in brain cells.
Researchers discovered lonsdaleite in ancient dwarf planet meteorites, confirming its existence and potential industrial applications. The unusual structure of lonsdaleite could help inform new manufacturing techniques for ultra-hard materials.
A study published in Animal Behaviour found that female Kinda baboons with strong social connections and higher ranks have babies that mature faster. This allows mothers to redirect their energy towards reproduction sooner.
A new study finds that older children are more likely to effectively test surprising claims made by adults, suggesting an increase in skepticism and intentional exploration. As a result, their exploration becomes more targeted and efficient.