A complex microbial community comprising bacteria, fungi, and oomycetes is beneficial for plant growth. Inactivation of the plant innate immune system shifts this balance, making the fungal load a primary cause of disease. Bacterial partners residing in roots provide an additional layer of protection.
A new study found that vaccinated UK healthcare workers who were previously infected with different COVID-19 variants show varying levels of protection against new variants. The results suggest that the sequence of variant exposure influences immunogenicity profiles, highlighting the need for tailored vaccine development.
A Michigan Medicine study combined genetic samples from patients of different ethnic backgrounds, identifying two new psoriasis genetic signals. The inclusion of South Asian subjects allowed researchers to pinpoint several genetic variations within HLA genes that are likely to play a causal role in psoriasis.
Researchers have expanded the number of naturally occurring CRISPR-Cas systems, giving a wealth of potential new tools for large-scale gene editing. The discovery could lead to treating complex diseases associated with multiple genes.
A new study by the Keck School of Medicine of USC finds that Medicaid expansion is associated with a significant reduction in mortality rates. The study, which tracked data from 2014-2018, found that expanding Medicaid coverage resulted in an estimated 3.8% decrease in adult deaths per year.
A new study led by Rice University engineers finds that microplastic pollution contributes to the spread of antibiotic-resistant genes. The researchers discovered that aging polystyrene breaks down into microplastics with high surface areas, trapping microbes and leaching chemicals that enhance gene transfer.
Scientists at deCODE genetics analyzed levels of 4,719 proteins in plasma from 35,559 Icelanders, finding 18,084 associations between sequence variants and protein levels. The study integrated these findings with disease and trait associations, revealing novel connections.
A local health department in Indiana used surveillance data to identify neighborhoods with high disease burden and set up test sites, resulting in a decline in new cases among targeted groups. The success of this intervention highlights the importance of using data to address systemic racism and promote health equity.
Researchers at Harvard have successfully observed quantum spin liquids, a previously unseen state of matter that has been elusive for nearly 50 years. By manipulating ultracold atoms in a programmable quantum simulator, the team was able to create and study this exotic state, which holds promise for advancing quantum technologies.
Researchers have discovered molecules that could be candidates for contraceptives or fertility enhancers using human blastoid models. These models also show promise in improving the self-organization of stem cells during IVF procedures.
Researchers at Johns Hopkins APL aim to create an ideal baby monitor that filters out unwanted noises, ensuring parents don't miss infant cries. The team's open-source device uses audio processing hardware to filter out background sounds, improving the overall baby monitoring experience.
The newly discovered planet is classified as a rocky planet and has similarities to Mercury, with a mass 55% of Earth's. Its high density indicates an iron core, but the surface temperature could reach up to 1500 degrees Celsius due to its proximity to its star.
The BESIII experiment has made significant contributions to understanding the internal structure of baryons. By measuring proton and neutron form factors, the team has clarified long-standing tensions between previous experiments. The study also reveals new insights into the interactions and fundamental structure of baryons.
Researchers developed a kinetic hypothesis governing the evolution of the Last Universal Common Ancestor (LUCA) based on simulation experiments. They discovered a kinetic factor that governs the flow of chemical reactions in the TCA cycle, validating their hypothesis for deep-branching bacteria and archaea.
A new floating robotic film can hoover oil spills at sea or remove contaminants from drinking water, using a pulsing motion inspired by water striders. The film is powered by light and fueled by water, making it sustainable and reusable.
Researchers at University College London have successfully grown mini-stomach organoids, which could help study how SARS-CoV-2 affects the stomach. The study found that the virus replicates more noticeably in child and late fetal cells, leading to the death of delta cells that produce a hormone called somatostatin.
Researchers have discovered new genetic variations associated with developmental stuttering, offering new therapeutic directions to improve outcomes. The study found that stuttering is polygenic, meaning multiple genetic factors contribute to and protect against the condition.
A bioinspired hierarchical porous membrane, based on intrinsic microporosity polymers, was developed to enhance uranium extraction from seawater. The membrane achieves higher numbers of interconnected multiscale channels, improving adsorption performance.
A new study from Karolinska Institutet and the University of Helsinki reveals how integrating digital tools, classical laboratory tests, and biomolecular measurements can enable individualized disease prevention. The researchers also found significant correlations between health risks and molecular factors associated with overweight, d...
Researchers found that gut microbiome changes can reduce b-amyloid deposits in male mice, indicating a potential target for preventing and treating dementia. Daily fecal matter transplants restored the pre-antibiotic microbiome, suggesting microglia memory plays a role.
A new MIT study uses climate modeling to reconstruct global hurricane activity, finding a significant increase in North Atlantic hurricanes over the last 150 years. In contrast, global hurricane frequency remains unchanged. The study's findings suggest regional climate variations play a key role in shaping hurricane patterns.
Researchers developed a new kind of organoid that grows both heart and gut cells together, mirroring their cooperation in embryonic development. This breakthrough could improve understanding of tissue communication and inform research into congenital disorders.
Researchers have developed a novel method to improve the efficiency of inverted architecture perovskite solar cells by introducing organic halide salts at both interfaces. This approach has achieved a power conversion efficiency of 23.7%, the highest reported to date, while also improving device stability.
Researchers use speaker shakers to generate vibrations in a plate, creating sound waves that constructively interfere at the target minifigure. The focused energy knocks over the single Lego minifig without disrupting the surrounding minifigs.
The global plastics supply chain has a significant impact on the climate, with production accounting for 96% of total greenhouse gas emissions. The use of coal-based energy in plastic production is driving this growth, with emissions quadrupling since 1995 and causing health issues like air pollution and asthma.
A study found that racial disparities in mammography screening worsened after COVID-19 closures, with non-white patients facing reduced access to facilities. Early interventions aimed at expanding access to these facilities helped to recover late recovery volumes for patients of races other than white.
Researchers from TROPOS and partners developed innovative air quality models to predict solar radiation and PV output. The study found a clear gradient in solar energy across Germany, with aerosols dimming energy in the east compared to the west.
Researchers have developed a high-resolution radar sensor that can reliably distinguish between cars and pedestrians, providing counts, speed, and direction of each moving target. The sensor outperforms cameras in low-visibility conditions and beats conventional radar by providing a richer picture.
Researchers aim to develop AI agents that reuse information, adapt quickly to new conditions and collaborate by sharing experiences. The goal is to enable machines to continually learn from their collective experiences and improve performance on novel and previous tasks.
A multicenter clinical trial demonstrates insulin secretion from engrafted stem cells in patients with type 1 diabetes. The study shows 20% reduced insulin requirements and 13% more time spent in target blood glucose range over a one-year follow-up period.
Researchers at Georgia State University have developed a new candidate antiviral drug, 4’-FlU, which shows potent activity against SARS-CoV-2 and other respiratory RNA viruses. The study demonstrates that 4’-FlU induces termination of the viral polymerase, aborting replication and offering a strong therapeutic asset.
Researchers provide evidence that mammalian and avian primitive streaks evolved independently, using different mechanisms to form the body plan. They suggest alternative landmark for ethical oversight in human embryological research.
Women living in neighborhoods with more green space experienced fewer PMS symptoms, including anxiety, depression, difficulty sleeping, and breast tenderness. Long-term exposure to green space was found to have beneficial effects on psychological symptoms of PMS.
Researchers found that increasing food amount elevates intestinal absorptive surface and function due to enhanced PPARα expression. Food restriction reverses this process, suggesting potential avenues for limiting obesity.
The state of Georgia could dramatically reduce its greenhouse gas emissions by using onsite electric power, creating new jobs and a healthier public. CHP systems can be 85-90% efficient, reducing peak demand on the grid and providing ultra-high system efficiencies, cleaner air, and more affordable energy.
Researchers found that genomic screening can identify patients at risk for heart disease due to amyloidosis. The study used data from the MyCode Community Health Initiative and electronic health records to determine how often patients with specific transthyretin variants showed signs of cardiomyopathy.
A cluster-randomized controlled trial in rural Bangladesh shows that proper mask-wearing significantly reduces symptomatic SARS-CoV-2 infections. Mask distribution and promotion increased community-wide mask-wearing by 29% and reduced reported COVID-like illness, especially among high-risk individuals.
A team from UNIGE found that dopaminergic neurons in the reward system are responsible for motivating social interactions. The study used mice to demonstrate how these neurons release dopamine, crucial for motivated behaviors and learning.
A study found that nearly two-thirds of US states failed to follow CDC guidelines for prioritizing cancer patients for COVID-19 vaccinations. The lack of clarity in defining qualifying cancer diagnoses led to unequal vaccination priority, leaving vulnerable patients at risk.
Researchers at UC3M found that Facebook ads can target a specific person with just four rare and specific interests. This nanotargeting ability exposes users to new risks, including potential identification without consent. The study highlights the need for advertising platforms to protect individual privacy.
After the 2012 US Preventive Services Task Force (USPSTF) statement discouraging routine prostate-specific antigen (PSA) testing, rates of prostate cancer screening and biopsy decreased across racial groups. However, Black men had higher rates of local and metastatic prostate cancer despite similar screening rates.
Researchers found that teams with autonomy to choose ideas or team members perform better than those without autonomy. Choosing ideas leads to a stronger match of interests and prior network contacts, boosting confidence and motivation. However, overconfidence can lead to complacency when too much autonomy is given.
Researchers at University of Helsinki have developed a new method to speed up calculations on quantum computers, reducing the number of measurements required and increasing efficiency. This breakthrough could lead to faster and more sustainable quantum computing.
Researchers developed a molecular device that converts infrared light to visible light, expanding detection capabilities. The device uses tiny vibrating molecules and metallic nanostructures to enhance conversion efficiency.
Researchers at the University of Cambridge have developed a new concept for detecting infrared light by converting it into visible light, easily detectable by modern cameras. This innovation enables the detection of mid-infrared light using molecular frequency upconversion with dual-wavelength hybrid nanoantennas.
Genetic variants at 67 genomic regions were found to contribute to increased risk of age-related hearing loss. Visualized proteins reveal molecular components critical for sound conversion and transmission.
Researchers at Tel-Aviv University have shed light on the Sigma-1 receptor's topology and function in neurodegenerative diseases. The study reveals that the receptor is retained in the endoplasmic reticulum and its amino end faces the cytoplasm, providing a crucial mechanism for therapeutic approaches to alleviate suffering from ALS.
A new technique using thin-film neural networks (TFNNs) improves processing times for all-optical neural networks and enables fast optimization of photonic devices. The approach accelerates the design and fabrication of multilayer thin films, mimicking human retina cells.
A study by the University of Toronto's Rotman School of Management found that predictive analytics can increase revenue by $500,000 to $1 million for manufacturers who invest in IT capital, educate their workforce, and implement high-efficiency manufacturing processes. The research team surveyed over 30,000 manufacturers and found that...
Researchers identified a mechanism for how genetically defective cells mutate to survive stressful situations, such as drug treatment. Understanding this resistance mechanism could lead to the development of new strategies to delay or prevent cancer drug resistance.
A study found significant declines in daily steps and increases in clinical depression risk among college students one year into COVID-19. Physical activity levels failed to return to pre-pandemic levels, while screen time remained higher than before.
Researchers discovered a newly defined domain in a protein that regulates gene expression under high-energy conditions. Cells adapt to changing nutrient environments by switching between specialized gene expression programs, which are triggered by different molecular tags on histones.
A study by Brynn Kimber and team reveals killer whales spending more time in the Arctic due to reduced sea ice, posing new threats to prey species. The warmer climate is altering the predators' hunting patterns, leading to increased risks for endangered bowhead whales.
A new study demonstrates that restoring Indonesian peatlands can reduce the impacts of peatland fires on the environment, climate, and human health. The analysis suggests that effective restoration will outweigh the cost of restoration, providing economic savings of up to $8.4 billion.
A recent study published in PLOS Pathogens found that the COVID-19 Delta variant may have a reduced ability to be neutralized by vaccines. The researchers analyzed serum samples from vaccinated individuals and found that the Delta variant was more effective at evading vaccine-induced immunity than other variants, such as Beta and Alpha.
Researchers developed a new method to significantly enhance thermoelectric voltage at low temperatures by creating laminate structures with transition metal oxide and insulating layers. The 'phonon-drag effect' is responsible for the enhancement, where flowing phonons drive electrons to produce extra thermoelectric voltage.
A subminiature multifunctional brain chip has been developed to analyze brain activity from multiple aspects. The chip integrates a fluid channel for extracting cerebrospinal fluid, injecting medicine, and measuring brain signals, minimizing brain damage and enabling precise analysis of neurotransmitters and brain signals.
Researchers have identified pigtailed macaques as a suitable animal model for studying two emerging tick-borne hemorrhagic viruses, Kyasanur Forest disease and Alkhurma hemorrhagic disease. The study found that infected macaques exhibited symptoms similar to those in humans, including loss of appetite, dehydration, and hemorrhaging.
Research from Flinders University found self-regulatory control and evaluative bias towards soft drinks associated with increased consumption. The study aimed to identify new methods to help habitual soft drink users regulate their intake. Young adults are the core consumers of soft drinks, posing a major public health problem.
Researchers found that adding a specific bacterium to the gut microbiome of mice with colon cancer increased immune cell activity and reduced tumor size. The study suggests leveraging gut microbiota to enhance anti-tumor immunity in advanced colon cancer, offering a promising new approach for treatment.
Researchers at Johns Hopkins Medicine have discovered that manipulating certain nerve cells may trigger the formation of new heart muscle cells, restoring heart function after heart attacks. The study found that removing specific genes associated with circadian rhythms increased neonatal heart size and cardiomyocyte numbers by up to 10%.
A new study from Pusan National University suggests that phonological awareness (PA) and phonics instruction can significantly improve the reading skills of English language learners. The meta-analysis of 46 studies found a moderate effect of PA and phonics on word reading, but a larger impact on pseudo-word reading.
A Norwegian study reveals that out-of-hours emergency doctors with higher admission rates inflict significant unnecessary costs on hospitals. The study found that patients seen by these doctors have a greater chance of hospital stays, particularly those over 69 years old.
Scientists from Tokyo Institute of Technology have developed a genetically encoded probe to visualize active transcription sites in living cells. The probe successfully identified phosphorylated Ser2 in RNA polymerase II, allowing for the localization of elongation phase transcription sites in real-time.
Scientists from TUM and Google Quantum AI used a highly controllable quantum processor to simulate exotic particles called anyons, which can emerge as collective excitations in two-dimensional systems. The study reveals the properties of these particles through braiding statistics, a key feature of topologically ordered states.
A global study found that one in 11 stroke survivors experienced anger or emotional upset in the hour leading up to their event, with a 30% increased risk. Heavy physical exertion was also linked to an approximately 60% increase in intracerebral hemorrhage risk.
A global group of researchers, industry stakeholders, and consumers have launched a networking hub to ensure the quality, accuracy, and accessibility of wearable fitness devices. The network aims to develop a standardized testing pathway and improve data standardization across devices.
A deep-learning model called D-SCRIPT predicts protein-protein interactions from primary amino acid sequences with high accuracy. The model enables the detection of functional subnetworks and can be applied to many species, including those with rare or lacking PPI data.
Recent research shows differences in Russian and US approaches to emotion, with Russian parents reading stories featuring negative emotions to their children. This highlights cultural nuances in socializing emotions before school age.
A study by FAU Harbor Branch reveals that even properly functioning septic systems contribute to nitrogen pollution in the Indian River Lagoon. Groundwater samples showed higher dissolved nutrient concentrations than surface waters, indicating contaminated groundwater as a major source of nutrient loading.
Researchers from Osaka University have successfully grown high-quality magnetite thin films on a hexagonal boron nitride substrate without compromising the film's properties. This breakthrough enables the development of flexible spintronics devices with preserved electronic and magnetic properties.
A new study reveals the vital role primary school teachers play in supporting families during home schooling, particularly for middle-income families who struggle to balance work and childcare responsibilities. The research highlights the range of resources and services provided by teachers to help mitigate socio-economic disadvantages.
The Patient-Centered Outcomes Research Institute (PCORI) Board approved funding for nine new comparative clinical effectiveness research studies addressing various health conditions. These studies focus on telehealth and mobile health strategies, reducing disparities in maternal health, and improving care for people with intellectual a...
A study by the Paul Scherrer Institute finds that blue hydrogen can play a positive role in the energy transition under certain conditions, especially when carbon capture and storage is used effectively. However, methane leakage along the supply chain can reduce its climate benefits.
A new study reveals Native American deaths from COVID-19 are substantially higher than other racial groups, with poorer living conditions and limited access to healthcare exacerbating the issue. The researchers advocate for increased funding and policies to improve public health and address these structural inequalities.
A blood test for HPV-associated head and neck cancer was found to be more accurate, faster, and cheaper than conventional methods. The test detected DNA fragments of HPV in the blood and was combined with routine imaging and physical exam findings for a fully non-invasive diagnostic approach.
Researchers have identified a genetic variant in the B4GALT1 gene that may confer protective effects against cardiovascular disease, characterized by lower LDL-C levels and decreased fibrinogen. The discovery could inform novel therapeutic approaches to decreasing or preventing CVD.
Scientists used single-cell sequencing to analyze over 150,000 cells from 11 tumor samples, discovering novel mechanisms of tumor development and identifying potential targets for therapy. The findings may lead to personalized medicine and improved treatment options for gynecologic cancers.
Researchers have discovered that certain microbes can prevent Clostridioides difficile infection by consuming nutrients essential for its growth. This new understanding challenges existing approaches to probiotic treatment options, which focus on restoring secondary bile acids.
Researchers found 2.4 times the rate of arbovirosis as originally reported, including coinfections, suggesting underestimation of the incidence of the three viruses. The study enriches epidemiological information on these arboviruses, which can help improve estimates of burden and resource allocation.
SourcePLOS·JournalPLOS Neglected Tropical Diseases·TypeExperimental study·DateDec 2, 2021
Room attendants, largely feminized and immigrant workers, face precarious conditions, including physical labor exploitation and lack of social protection. Las Kellys employs three types of subversion tactics to redefine their work, highlight central roles, and fight for dignity.
Researchers examined the risk of developing diabetes-associated eye disorders among children diagnosed with type 1 or type 2 diabetes. The study found a significant association between diabetes diagnosis and increased risk of diabetic retinopathy and glaucoma in childhood.
The study found that many museums struggled to adapt their in-person programs to online format, leading to decreased engagement and revenue. However, some institutions successfully transitioned to virtual programming, offering creative and engaging content for underserved audiences.
The US FDA's early approval of Aduhelm sparked worries about the lack of post-approval studies. Insufficient company incentives and patient participation hinder meaningful trials.
A study by Imperial College London found that the first SARS-CoV-2 spike protein encountered through vaccination or infection influences subsequent immune responses to current and future variants. This 'immune imprinting' affects the rate of decay of protection and impacts antibody levels over time.
Researchers found that damaged telomeres increase the expression of ACE2, the human SARS-CoV-2 cell receptor, leading to increased viral susceptibility in the elderly. This DNA damage response is triggered by telomere shortening and dysfunction in aging cells.
Research found a significant correlation between increased atmospheric temperature and asthma attacks in children. Lower SO2 levels during the state of emergency also contributed to reduced asthma exacerbations, suggesting that environmental factors play a crucial role in asthma management.
Researchers create a porous microneedle to deliver CAR T cells into solid tumors, improving anti-tumor effects. The strategy showed enhanced tumor infiltration and amplification of CAR T cells in melanoma models.
Researchers found that macrophages play a central role in COVID-19-related respiratory failure, leading to fibroproliferative ARDS and prolonged ventilation. Extensive tissue damage and scar tissue formation are characteristic of severe lung failure.
Scientists at Paderborn University have demonstrated the spatial confinement of a light wave to a point smaller than the wavelength in a topological photonic crystal. This finding enables novel unidirectional waveguides that transmit light without back reflection, even with arbitrarily large disorder.
The study found that certain grain boundaries in strontium titanate exhibit enhanced thermal expansion, leading to potential material failures. This discovery highlights the importance of grain boundaries in material properties and has implications for selecting suitable materials for various applications.
Researchers have discovered GJ 367b, a sub-Earth exoplanet with a density similar to that of pure iron, which orbits its red dwarf star host in under 24 hours. The planet's size and mass indicate it has lost its outer mantle, suggesting an iron-rich core, similar to Mercury's interior structure.
Engineered biofilms made of E. coli bacteria exhibit emergent drug resistance properties when printed using the new technique. This study provides valuable insights into harnessing the beneficial aspects of biofilms while combating their negative effects, potentially leading to breakthroughs in medicine and materials science.
A study found that COVID-19 vaccination significantly lowers the risk of SARS-CoV-2 infection among patients with cancer. The vaccinated group had a lower incidence of COVID-19 compared to those who did not receive the vaccine.
Researchers studied the usage of population terms in a 70-year publication history of the American Journal of Human Genetics, finding changes in word usage and associations between terms. The study suggests that structural racism, social trends, and changing views on social constructs may be linked to these changes.
A recent study found associations between air and water pollutants and changes in the human sex ratio at birth. Pollutants such as PCBs, iron, lead, and chromium were linked to an increased or decreased ratio of baby boys to girls.
SourcePLOS·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateDec 2, 2021
Research found that households in different cultures are motivated to adapt to climate change by factors such as self-efficacy and perceived costs. However, these drivers vary across countries, with previous flood experiences having little effect on adaptation intentions in some regions, but discouraging it in others.
Research suggests that adolescents who struggled with difficult peer interactions before the pandemic did not experience increased depression and anxiety during isolation. In contrast, teens in general reported increased symptoms. The findings imply that COVID isolation may have had a different impact on teenagers with problematic peer...
Researchers at Harvard Medical School identified likely mutations that would allow the virus to evade immune defenses, including natural immunity and vaccine-developed antibodies. The study provides important clues about areas of concern with omicron variant and serves as a primer for future variants.
A new study identifies customers' political ideology as a driver of satisfaction, finding that conservatives are consistently more satisfied than liberals. Companies can use this insight to tailor their products and services to boost customer satisfaction and drive sales.
A new study led by NCAR finds that the Southern Ocean absorbs significantly more carbon than it releases, clarifying its role as a carbon sink. Airborne measurements of carbon dioxide reveal critical patterns in the global carbon cycle, providing insights into climate change projections and emission reduction measures.
Phycocyanin, a natural food colorant, loses its hue when exposed to acidified beverages. Cornell researchers stabilized the protein using X-ray beams, allowing it to retain its vibrant blue color. The study provides insights into the molecular structure of phycocyanin and its interaction with light.
A team of scientists measured the masses of two young giant planets in a 20 million-year-old system, finding they reached their final size at an early stage of evolution. This challenges current models, suggesting that giant planets can contract and mature rapidly.
A recent study found that people who are open to technology but perceive a lack of access to it (tech seekers) are most likely to want to use AI-powered symptom checkers. The tool's adoption is also influenced by perceptions about trust and output quality, with skeptics being the least likely group to adopt it.
A new study from the University of Bath is shedding light on the behavior of saline solutions under extreme conditions, a crucial step towards carbon storage in deep-sea aquifers. The research uses neutron diffraction to examine the interaction between salt ions and water molecules at high pressures and temperatures.
A recent study published in JAMA Network Open found that women with advanced melanoma are more likely to die from checkpoint inhibitors, a class of cancer treatment. The researchers analyzed health records of 1,369 patients and discovered a significant difference in mortality rates between men and women treated with the same combinatio...
A new white paper shares practical strategies to inform stewardship efforts and ensure appropriate use of antibiotics, citing the public health crisis of antibiotic resistance leading to 23,000 preventable deaths each year. Implementation science principles can bridge the evidence-practice gap.
A new study found a dramatic increase in people with co-occurring mental health needs and substance use disorders in B.C. prisons, reaching 75% of the prison population. The study calls for more treatment and efforts to address social and structural inequities.
New research found that even with proper PPE, medical instrument processing personnel are frequently exposed to splashing liquids during routine activities. The study highlights the need for additional research to support evidence-based guidelines and recommends a combination of engineering solutions and improved protective gear.
Researchers found that increased physical activity reduced mortality risk in all groups, but health benefits plateaued in healthy individuals and those with cardiovascular risk factors. In contrast, cardiovascular disease patients showed no further benefit beyond a certain volume of physical activity.
Astronomers have discovered an ultra-short-period planet GJ 367 b, which orbits its star in just eight hours and has a radius of 72% that of Earth. The planet's mass is 55% of the Earth's, indicating it likely has an iron-rich core, similar to Mercury's interior.
A study found that many Medicaid-enrolled women in Virginia were unaware of dental pregnancy benefits, despite comprehensive coverage enacted in 2015. The survey revealed significant gaps in oral health knowledge among reproductive-age women by insurance status, with Medicaid-enrolled women facing barriers to care at higher rates.
Cedars-Sinai researchers discovered that interleukin-6 mediates delirium-like phenotypes in mice with urinary tract infections, highlighting a potential therapeutic target. The study suggests that modulating immune responses may help alleviate UTI-induced delirium.
Researchers have developed a new two-photon microscope that provides subcellular resolution of multiple brain regions, enabling monitoring of neural circuitry in mammals. The microscope has the largest field of view and imaging speed to capture changes in neuron activity during behavior.
The climate crisis affects Antarctic fur seals by limiting krill availability, decreasing their reproductive success, and increasing predation on pups. Satellite tracking reveals that males adapt to the cold environment by diving deeper in search of food.
A new Northwestern study reveals that brain motor neurons degenerate early in diseases like ALS, sending warning signals and showing defects. Targeting the brain's motor neurons could lead to long-term and effective treatment strategies.
A recent study published in Frontiers in Cellular and Infection Microbiology found a significant increase in sexually transmitted infections (STIs) among girls and young women in western Kenya, coinciding with the COVID-19 pandemic. Researchers attribute this rise to increased stress-related changes in the vaginal microbiome.
Researchers develop theory on exploiting space reflection and time reversal symmetries to control transport and correlations in quantum materials. The discovery may lead to the design of future quantum devices relying on strong correlations and exceptional points in oligomer chains.
The Seattle Space Needle renovation incorporated acoustic designs to limit sound transmission, enhancing visitor experience. Acoustic materials and effective reverberant sound control were selected for the observation levels and restaurant.
Researchers at Hospital Gregorio Marañón and UC3M developed a navigation system combining surgical navigation, three-dimensional photography, and augmented reality to estimate bone fragment positions during surgery. This system has been used on 7 patients with optimal results, reducing dependency on surgeons' experience.
Coastal organisms thrive on floating plastic debris in the North Pacific Subtropical Gyre, expanding their biogeography. The discovery reveals that plastic pollution is providing a habitat for coastal species to survive and even thrive in the open ocean.
Tiny fixational eye movements, beyond human awareness, are critical for fine details and everyday tasks. Microsaccades cause transient visual suppression during gaze shifts, but vision recovers rapidly at the center of gaze, leading to enhanced overall visibility.
Researchers have created a material system exhibiting unusually long-range Josephson effect, enabling macroscopic quantum coherence and potential for spintronic applications. The discovery of 'triplet' superconductivity, where electrons with the same spin circulate, expands possibilities for low-power consumption devices.
A new report from Portland State University aims to improve mobility and quality of life for older adults by developing forms of assistance and educational strategies. The study found that low-income older adults faced significant barriers to transportation, including fear of public transit during the pandemic lockdowns.
The Cumbre Vieja volcano eruption revealed a four-year period of increased seismic activity, suggesting early warning signs of unrest. This discovery has significant implications for eruption forecasting at quiescent volcanoes.
Researchers created a single-cell map of corn's root, identifying key regulators of cellular diversity that help crops tolerate drought and flooding. The study found that the genetic regulator SHORT ROOT (SHR) plays a crucial role in expanding cortex tissue, leading to increased tolerance of climate stressors.
A team of researchers has developed a Dynamic Sampling Platform to analyze cells in real-time, overcoming the time-consuming and expensive process of biomanufacturing. The platform provides insight into cell behavior and biochemical information needed for process control, potentially lowering the cost of cell therapies.
A team of biologists identified the fungus Verticillium dahliae's effector molecule VdAMP3, which targets beneficial organisms in the plant's microbiome to promote infection. This discovery highlights the importance of considering the entire microbiome when understanding disease.
A new study found that children's books in long day care centres are often not inclusive of diverse characters and perpetuate traditional gender roles. The research team analysed eight long day care centres in Australia and the USA, finding that only 10% of frequently read books featured diverse characters.
Researchers identified 187 North Atlantic right whales in the Gulf of St. Lawrence, a 40% segment of the catalogued population, with most returning every year for up to 5 months. The study highlights the importance of the Gulf as a habitat and provides valuable information for developing protection measures.
Scientists have developed a technology called LUX-MS to study the organisation of cell surface molecules, revealing that proteins work together to fulfil cellular functions. The method can detect the proximity of molecules on the cell surface with nanometer-scale precision.
Researchers developed an automated system using deep learning to detect COVID-19 lesions in CT chest scans, achieving 99% accuracy. The system can provide high-precision data for doctors to make robust and accurate diagnoses.
Researchers from Ruhr-University Bochum identified 14 new types of cross-site leak (XS-Leak) attacks on web browsers. XS-Leaks allow malicious websites to grab personal data by interacting with other sites in the background, with popular browsers like Chrome and Firefox vulnerable to multiple attacks.
A recent study published in Canine Medicine and Genetics reveals that most dog breeds are highly inbred, with an average inbreeding rate of 25% or sharing the same genetic material with a full sibling. This high level of inbreeding contributes to increased disease and healthcare costs throughout a breed's lifespan.
Researchers at Lehigh University are working on a project funded by the Good Food Institute grant to adapt human tissue engineering techniques for growing meat in the lab. The team is developing a scaffold for meat cells to grow on and using electrochemistry, nanomaterial design, and liposomal delivery vehicles to promote fibrous growth.
The Center for Justice Research at Texas Southern University has received a $410,000 grant from the Thurgood Marshall College Fund to continue its work on building and sustaining diversity within criminal justice research. The center will establish a network of systemic change in education for graduate students and faculty.
A Washington State University study found that cannabis vapor exposure lowered sperm counts and slowed movement in male mice and their sons. The study suggests that cannabis use may be detrimental to male reproductive function, contributing to declining human sperm counts.
Researchers have discovered a genetic variant associated with lower LDL cholesterol and fibrinogen levels, significantly reducing the risk of heart disease in the Amish population. The variant is found in nearly 12% of those living in Lancaster county, Pennsylvania.
A team of researchers used deep learning to analyze cardiac images and identified genetic variations linked to aortic size. The findings may lead to the development of a polygenic score to identify individuals at high risk of aneurysm, as well as new drug targets for aortic enlargement.
Researchers found that consumers are willing to pay a small discount for imperfect carrots, maxing out at 40% of misshapen carrots. Marketing messages promoting the nutritional quality and societal benefits of ugly produce were more effective in convincing consumers to buy.
A new study in Scientific Reports reveals the first palaeontological site with multiple, exceptionally complete dinosaur skeletons from Italy. The Villaggio del Pescatore site in north-eastern Italy has yielded seven individuals of Tethyshadros insularis, the biggest and most complete dinosaur ever found in Italy.
Researchers found that repeated fast charging causes atomic-level damage to the graphite particles in lithium-ion batteries, leading to degradation. This damage hinders the intercalation process, preventing lithium ions from moving into the particles, and ultimately impairing battery performance.
Researchers found that intense volcanic activity led to a surge in phosphorus levels, driving ocean oxygen levels down and triggering a severe mass extinction. The study suggests that natural weathering of volcanic material may have been responsible for the sudden cooling events.
Scientists at Chalmers University of Technology discovered a way to create a stable resonator using two parallel gold flakes in a salty aqueous solution. The structure can be manipulated and used as a chamber for investigating materials and their behavior, with potential applications in physics, biosensors, and nanorobotics.
A UK trial shows six different COVID-19 boosters are safe and stimulate strong immune responses in people who have previously received a two-dose course of ChAdOx1-nCov19 or BNT162b2, according to the first randomised trial of boosters given after two doses. The study found varying levels of protection against COVID-19 infection and ho...
The COVID-19 pandemic has exposed weaknesses in the criminal justice system, highlighting issues with family and domestic violence, gang activity, and police-community interactions. Scholars from the American Society of Criminology investigate these concerns in a special issue, exploring lessons learned and policy implications.