Researchers discovered a prominent 1D electronic edge state near the Fermi level at the step edge of TaAs crystals with Miller index (112). Calculations confirmed that small surface areas can preserve topological information, leading to the existence of 1D Fermi arc states at step edges.
A new study confirms that emissions from anthropogenic sources, including agriculture, landfill/waste, and fossil fuel industry, are the driver for the renewed rise of potent greenhouse gas since 2007. Global wetlands play a minor role with less than 20% contribution to atmospheric methane.
A study improved the pDSSAT model to analyze spatiotemporal patterns of winter wheat phenology and its drivers in China from 2000 to 2015. The results showed significant enhancements in simulation accuracy, particularly for anthesis and maturity dates.
Researchers found that aerosols had a significant impact on tropical cyclone TC Lupit as it approached the Asian continent. Direct aerosol-radiation interactions (ARI) weakened convection in the eyewall, while indirect aerosol-cloud interactions (ACI) enhanced convection and intensified the typhoon.
Researchers detected strong Bayesian evidence for a spatially correlated process with scalar transverse correlations, suggesting an alternative theory of gravity beyond Einstein's general relativity. The study uses the North American Nanohertz Observatory for Gravitational Waves' 12.5-year data set.
Researchers developed a photosensitizer with multiple properties that can be tuned to generate singlet oxygen and exhibit photothermal conversion. The work shows promise for multifunctional photo-theranostics and provides a prototype for designing high-performance PSs.
A systematic review of 21 placebo-controlled trials found hangover treatments to be ineffective due to low-quality evidence. Future studies should prioritize validated scales and increased female participation to provide accurate information on remedies.
Despite efforts to control river pollution, lake water quality has not improved as expected in China. Lake restoration and ecological management are key to addressing eutrophication and achieving sustainable development.
Researchers evaluated changes in calorie content at 59 large restaurant chains before and after implementing mandatory menu labels. After label implementation, restaurants reduced average calorie per item by 11%. The study aimed to understand the impact of labeling on menu nutrition.
Researchers discovered that human lung stem cells can undergo abnormal differentiation in response to injury from diseases like COVID-19 and pulmonary fibrosis. This aberrant process prevents the restoration of normal lung function, but the study also identified a potential therapeutic target for reversing damage.
New research suggests that ultra-low velocity zones in the deep mantle may be regions made of different rocks than the rest of the mantle, with compositions potentially linked to the early Earth. The study's findings imply the presence of layered structures within these zones, shedding light on their origin and evolution.
Researchers propose a new plate tectonic model explaining the closure of irregular oceans and formation of curved orogenic belts through rollback subduction and rotation of convergent blocks. The study provides critical constraints on the Central Asian Orogenic Belt using digital mapping and giant 'tightly folded' magmatic belts.
A survey study investigated the prevalence of missing medical care among Medicare beneficiaries during the COVID-19 pandemic. The study found that the gap in healthcare access has persisted and worsened over time, highlighting ongoing concerns about social determinants of health.
Researchers have developed a technique called cryobioprinting that combines bioprinting with cryopreservation to create frozen, complex structures. The technology allows for the fabrication of anisotropic tissues with microscale pores aligned in specific directions, opening up new possibilities for muscular tissue engineering and beyond.
Researchers at Cedars-Sinai have identified opportunities to use microgravity in space for large-scale stem cell production, disease modeling, and biofabrication. This could lead to breakthroughs in regenerative medicine and the development of new treatments.
A systematic review of 26 studies found that the British food environment hinders weight loss efforts and maintains obesity. Policymakers are advised to address this issue through effective policy changes to create a healthier food environment.
Experts from Charité – Universitätsmedizin Berlin will deliver SARS-CoV-2 tests and train laboratory staff to monitor the Mu variant, which has spread widely throughout Colombia. The team will also support local authorities with antibody testing and knowledge transfer to inform pandemic control decisions.
A new study published in Developmental Cell reveals the mechanism of membrane curvature that allows cells to form pockets to capture substances. The researchers used high-resolution fluorescence imaging to watch these pockets form within live cells, providing a clearer understanding of how cells 'eat' and consume substances.
The newly discovered Begonia giganticaulis, a type of plant genus Begonia, has been found to be the tallest species in Asia, reaching heights of up to 3.6 meters. Its conservation status is currently listed as Endangered due to its fragmentary distribution in southern Tibet.
The study found that cancer was the second leading cause of death globally in 2019, accounting for 10 million deaths and 23 million new cases. Despite increases in absolute burden, global age-standardized mortality and incidence rates decreased by 5.9% and 1.1%, respectively.
Researchers at South Ural State University have identified biomarkers for post-traumatic stress disorder (PTSD) in veterans with long-lasting symptoms. Gamma-aminobutyric acid levels were found to be the most sensitive indicator, differing from reference values even years after traumatic events.
Researchers have developed SEAKER cells, which combine target-seeking power with the ability to locally generate potent anticancer drug for double effect. The cells use an enzyme to release active prodrug at tumor site, killing both cancer cells and those nearby that do not contain the marker.
A study of 70 youth tackle football players aged 9-12 over four seasons found a significant association between head impacts and cognitive and behavioral outcomes. The research suggests that repeated head impacts in youth tackle football may lead to long-term consequences for young athletes.
A large US-based study found that optimal gestational weight gain ranges associated with lower infant illness and death risks exist for different maternal weight categories. The study used birth data to identify these ranges and provide insights into the relationship between maternal weight gain and infant health outcomes.
The study combined seven randomized clinical trials with 8,000 patients to compare overall and treatment-specific outcomes of Black and white men with localized prostate cancer who received radiation therapy. The results showed that there were significant racial disparities in response to radiation therapy for prostate cancer.
Researchers from the University of Oxford investigated the behavior of CO2 within a depleted hydrocarbon reservoir in Louisiana, USA. They found that up to 74% of CO2 was dissolved in groundwater, while microbial methanogenesis converted 13-19% of the injected CO2 to methane.
Researchers found that people infected with COVID-19 develop a wide variety of autoantibodies up to six months after recovery, and these autoantibodies persist over time. The study suggests that understanding these autoantibody responses could help identify ways to treat and prevent long-term symptoms.
A global trial led by UCL found that a dolutegravir-based regimen reduced treatment failure among young people aged three to 18 by around 40% compared to standard treatments. The study also showed better growth and lipid profiles in children receiving dolutegravir, making it an effective option for treating HIV in children.
A study of nearly 12,000 obese patients found that substantial weight loss achieved through weight loss surgery was associated with improved outcomes after contracting COVID-19, including lower risk of severe disease. The results suggest that weight loss surgery may help mitigate the severity of COVID-19 in individuals with obesity.
Scientists have grown rousette bat 'organoids' that reproduce intestines in vitro, providing a new model for studying virus-bat relationships. The organoids were found to be susceptible to certain viruses but not others, offering insights into why bats can host multiple pathogens without getting sick.
A study of over 6,000 women found that US-born Black women are at higher risk of preeclampsia, but this is not solely due to their racial background. Factors such as biology, social and cultural elements, and access to healthcare also play a role in this disparity.
A study conducted at the University of Turku found that following a healthy diet in early pregnancy can significantly reduce the risk of developing gestational diabetes. The research revealed that a diet high in saturated fats and low in essential nutrients increases inflammation and raises the risk of gestational diabetes.
A meta-analysis of seven randomized trials found that Black men with localized prostate cancer had lower recurrence, metastasis, and mortality rates compared to white men. The study challenges the common belief that Black men with prostate cancer have a worse prognosis.
Researchers have shed light on the role of RUVBL1 and RUVBL2 proteins in the assembly and maturation of the spliceosome, a complex involved in cell splicing and alternative splicing. The study provides insights into the mechanisms responsible for the maturation of the splicing machinery.
A Cleveland Clinic study found that prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe COVID-19. Patients who underwent weight-loss surgery had better clinical outcomes, including reduced hospitalization and need for supplemental oxygen.
Research found marked decreases in orphanhood, especially double orphanhood, among adolescents in Rakai, Uganda, corresponding with the rise of antiretroviral therapy and male medical circumcision. The study suggests that HIV combination prevention reduces mortality among adults and orphanhood among their adolescent children.
Researchers have discovered a pattern of immune activity in normal pregnancies that can detect abnormalities and predict complications. The study found elevated immune activation in the first three months, followed by a calmer phase, and higher activity in the last three months, especially when childbirth is imminent.
Researchers have successfully developed a type of self-healing perovskite solar cell by functional combination of PVP, which controls crystal growth and endows devices with self-healing ability in a moisture environment. The introduction of PVP also improves crystal growth with fewer defects and larger grains.
Researchers from Hefei Institutes of Physical Science have developed a lead-free composite shielding material with high shielding properties. The modified-gadolinium oxide/boron carbide/high density polyethylene composite shows excellent performance in shielding both neutrons and gamma rays.
A new study reveals distinct DNA methylation profiles of human microglia cells across different age groups, disease states, and brain regions. The researchers found that interindividual differences in methylation variability had a larger impact than regional or diagnostic differences.
Researchers found that e-cigarette use is associated with higher rates of smoking cessation among smokers who were initially not planning to quit. The study suggests that e-cigarettes may be a viable tool for helping smokers quit tobacco products.
A new study reveals that in many countries, there are significant gaps in care related to the importance of nutrition for maintaining kidney health. Nutritional interventions can slow kidney function decline and reduce symptoms.
Researchers found that infants with autism symptoms can show significant improvement in just a few months through targeted therapeutic interventions. The studies suggest that bridging the gap between early detection and intervention may significantly reduce the severity of lifelong developmental deviation.
Scientists from CNIO and Massachusetts General Hospital have developed new approaches to visualize DNA repair by analyzing hundreds of proteins at once. They discovered nine new proteins involved in DNA repair and identified key players in the process, which could lead to improved cancer treatments.
A new study found that COVID-19 vaccination during pregnancy elicits high levels of antibodies in both mother and baby, regardless of when it occurs. The research suggests that pregnant women should not delay vaccination until late pregnancy, as it is likely to be beneficial for themselves and their babies.
A new study published in the Journal of Oncology found that breast cancer patients treated at hospitals and health systems with integrative health services have a better chance of survival. These services include complementary and lifestyle therapies, such as nutrition and exercise counseling, in addition to medical cancer treatments.
A new inoculation method can identify resistance against one of the CLB pathogens, allowing breeders to select candidates for genetic material against the disease. This method uses detached leaflets for inoculation and offers an advantage in small experimental designs, enabling screening of soybean genetic materials.
A study published in JAMA Internal Medicine found that people with immune dysfunction, such as HIV infection or rheumatoid arthritis, had a higher rate of COVID-19 breakthrough infections after vaccination. These individuals also experienced worse outcomes compared to those without immune dysfunction.
A recent study by Xuedi Li and colleagues found that excessive screen time was associated with increased symptoms of depression, anxiety, and hyperactivity in children during the COVID-19 pandemic. The research suggests that parents should monitor their child's screen use to mitigate potential mental health effects.
Researchers from Egypt used 3D CT scanning to 'digitally unwrap' the mummy of Pharaoh Amenhotep I, dispelling a theory that 21st dynasty restorers reused old royal burial equipment. The study revealed that the priests lovingly repaired injuries inflicted by tomb robbers and preserved the pharaoh's jewelry and amulets.
A new study published in JAMA Psychiatry found no evidence that vitamin D supplementation improves mental or physical health symptoms in people with psychosis. High rates of vitamin D deficiency were observed, particularly among ethnic minority participants.
Researchers have created a cheap and rapid COVID-19 test using isothermal amplification, making it possible to detect any COVID-19 variants. The new system combines existing LAMP technology with novel coronavirus genome markers, allowing for quick detection without specialized equipment.
Scientists have developed a new technique to extract DNA from the 'cement' head lice that attached eggs to hairs of ancient humans. This method reveals clues about pre-Columbian human migration patterns in South America, allowing for the study of unique samples from mummified remains where bone and tooth samples are unavailable.
Researchers have discovered that ovarian cancer begins with cancerous lesions in the fallopian tube linings of women with BRCA-1 mutations. The study's findings hold promise for predicting which women will develop ovarian cancer years or decades in advance, allowing for early detection and prevention strategies.
The study found that the prevalence of serious hearing loss declined by 2.5% among older Americans between 2008 and 2017. Notably, females experienced a significant decline in serious hearing loss, with a 10% decrease in odds of serious hearing loss observed across all age cohorts.
Researchers found that the fetus uses a signal called IGF2 to control nutrient supply from the placenta. The team discovered that only the paternal copy of the IGF2 gene is active, while the maternal copy inactivates it.
A new study reveals that children globally will confront peers when rules are broken, but their approach differs across cultures. Children from rural areas tend to use verbal protests more than urban kids, who may rely on indirect methods like reputation to enforce compliance.
A study at the University of Helsinki found that the APOE4 allele may increase cerebral microhaemorrhages and mental fatigue in COVID-19 patients. The risk of developing severe COVID-19 more than doubled in carriers of this allele.
A clinical trial will harness synthetic chimeric antigen receptor (CAR) T cells to deplete immune B cells and plasma cells producing donor-specific antibodies, aiming to achieve a compatible kidney match for patients with pre-existing antibodies. The NIH-funded study, led by Penn Medicine, intends to begin enrolling patients in 2022.
Researchers developed OptoMYPT, an optogenetic tool that reduces actin and myosin-based contractile force. By applying blue light, they accelerated cell cleavage furrow ingression speed and disrupted cortical tension, revealing the importance of optimal forces for normal cell division.