What The Study Did: People with immune dysfunction such as HIV infection, rheumatoid arthritis and solid organ transplant had a higher rate for COVID-19 breakthrough infection and worse outcomes after full or partial vaccination compared with people without immune dysfunction in a study that included 660,000 patients who received at least one dose of a SARS-CoV-2 vaccine.
Authors: Jing Sun, M.D., M.P.H., Ph.D., of the Johns Hopkins University Bloomberg School of Public Health in Baltimore, and Rena C. Patel, M.D., M.P.H., of the University of Washington in Seattle, are the corresponding authors.
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(doi:10.1001/jamainternmed.2021.7024)
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