Vaccination
Articles tagged with Vaccination
State-level differences in HPV vaccine uptake among 13- to 17-year-old adolescents
The study found substantial state-level variation in HPV vaccine uptake, with Northeastern states exhibiting higher rates and Southern states showing lower rates. Several sociodemographic factors were not significant predictors of vaccination rates, highlighting the need for targeted interventions to improve vaccine uptake.
Pregnant women’s mental images are directly linked to vaccine hesitancy and uptake
A study of over 400 pregnant women found that vivid mental images are directly linked to their opinion of vaccines and whether they get vaccinated. Positive mental images were associated with increased vaccination rates, while negative images predicted higher hesitancy towards certain vaccines.
Mitochondrial stress identified as a key factor in rare myocarditis after messenger RNA vaccination
Review finds no direct link between aluminium adjuvanted vaccines and serious or long term health conditions
A systematic review of 59 studies found no association between aluminium-adjuvanted vaccines and serious or long-term health outcomes, including autism, type 1 diabetes, asthma, and myalgia. Persistent nodules or granulomas at the injection site were the most consistently documented reactions.
Study finds four of the CDC’s seven measles elimination status indicators missed
A study by Boston Children's Hospital researchers found that the US missed four out of seven measles elimination status indicators, with most at risk. The latest outbreak has spread continuously for over a year and affected 45 states since January 2025.
New research challenges understanding of mRNA vaccines and establishes innovative way to make them more effective
A new study by researchers at Mount Sinai overturns the assumption that immune cells are essential for generating immunity from mRNA vaccines. Instead, non-immune cells such as muscle and liver cells play a role in shaping the immune response.
Your nose is a battlefield
Researchers at La Jolla Institute for Immunology discovered that FluMist can trigger an immune response directly in nasal tissue, training immune cells to recognize and fight influenza virus infection. This response stays in the upper airways and cannot be detected via blood samples.
New study suggests seasonal flu vaccines may reduce severity of H5N1 bird flu infections
A new study suggests that seasonal influenza vaccines may significantly reduce the risk of death from H5N1 infection. The study found that vaccines including a specific component, neuraminidase N1, reduced H5N1-related mortality by approximately 73 percent in vaccinated animals.
Impact of removing the universal hepatitis B birth-dose vaccination in the US
Targeted birth-dose vaccine recommendation may increase neonatal HBV infections unless maternal screening improves or infant vaccination coverage increases. Universal screening and vaccination remain essential safeguards against these infections.
New study suggests reduced newborn hepatitis B vaccination coverage may increase infant infections
A recent study found that lower vaccination coverage among infants born to unscreened mothers is associated with a substantial increase in HBV infections. The researchers used simulation modeling to examine the impact of different levels of newborn vaccination coverage and maternal screening on HBV infection rates.
Economic impact of delaying the infant hepatitis B vaccination schedule
Brief delays in hepatitis B vaccine initiation result in substantial increases in virus infections, adverse health outcomes, and healthcare expenses. Economic evaluations reveal the significant financial burden of such delays on individuals and society.
New study examines measles vaccination coverage after a postelimination outbreak
A new study examined measles vaccination coverage in a primary care network following a large post-elimination outbreak. The findings show that MMR coverage remained below herd immunity levels, highlighting the fragility of measles elimination.
New study examines impact of pediatric influenza vaccination rates on U.S. healthcare resource utilization
The study found that low influenza vaccination rates among children are associated with increased healthcare visits, hospitalizations, and ICU admissions. Achieving a 70% immunization rate could prevent up to 2.2 million outpatient visits and 123 pediatric deaths during high-incidence flu seasons.
European Immunization Week 2026, For every generation, vaccines work: three countries reach 90% HPV vaccination target as Europe steps up action on cancer prevention
Three European countries reach 90% HPV vaccination coverage among girls by age 15, marking progress in cervical cancer prevention. HPV vaccination programmes show significant reductions in infections and precancerous lesions, with early administration increasing full protective potential.
mRNA vaccines follow unconventional immune path to destroy tumors
Researchers at WashU Medicine discovered that mRNA vaccines can trigger strong anti-tumor responses even without certain immune cell subtypes, suggesting a novel pathway for cancer treatment. The study found that both cDC1 and cDC2 dendritic cells play a role in stimulating T-cell responses.
Extend vaccination opportunities and involve community members in communicating about vaccines to boost uptake, say researchers
Researchers found that extending vaccination opportunities, involving community members, and providing financial incentives are effective ways to increase vaccine uptake. The study analyzed international trial evidence and highlighted the most effective components across different populations and contexts.
Influenza vaccine could protect against heart attack and stroke even among people who get infected
Researchers found that influenza vaccination reduced the risk of heart attack and stroke by half for those who got infected, even if they didn't get vaccinated beforehand. The study's findings suggest prioritizing influenza vaccination among high-risk populations could have significant public health impact.
Johns Hopkins team develops therapeutic, nasally delivered DNA vaccine for tuberculosis
The Johns Hopkins team developed a therapeutic intranasal DNA vaccine against tuberculosis that accelerated disease clearance, improved treatment outcomes, and stimulated immune responses. The vaccine combines two genes to direct the immune system to fight drug-tolerant bacterial persisters, showing promise for treating TB.
Inequalities in childhood pneumococcal vaccine uptake persist in England despite schedule change
Persistent inequalities remain a major barrier to achieving universal protection against life-threatening infections. The study found that PCV booster retention has dropped in England since the schedule change, disproportionately affecting children in more deprived areas.
Postacute sequelae following omicron COVID-19 in patients with cancer
Among highly boosted patients with cancer, overall postacute sequelae risk was not elevated compared to noninfected patients; hospitalized COVID-19 patients remained at increased risk despite therapeutics. Vaccination and boosting remain important in mitigating long COVID among immunocompromised patients
HPV vaccination uptake in adults shaped by knowledge and medical advice
A nationwide survey in Switzerland found that HPV vaccination uptake among adults was lower than among adolescents, with only 27% of those aged 18-45 vaccinated. The survey also revealed significant differences between genders, age groups, and levels of knowledge about HPV, highlighting the need for targeted information and tailored co...
Tsinghua University team discovers skin's hidden role in amplifying immune responses, paving way for novel vaccine adjuvants
Researchers reveal that skin-cell calcium channel TRPV3 is activated by plant-derived fragrant molecules, leading to enhanced immune responses and potential new vaccine adjuvants. The study provides a novel understanding of immune crosstalk and offers a safer approach to enhancing vaccine efficacy.
Engineered lipid nanoparticles reprogram immune metabolism for better mRNA vaccines
Researchers at the University of Pennsylvania developed lipid nanoparticles that modify immune metabolism to strengthen mRNA vaccines and reduce common side effects. The new lipid boosts the metabolism of immune cells, providing energy for the body's defenses while dialing down inflammatory signals.
ACP supports AAP’s evidence‑based childhood vaccine schedule
The American College of Physicians (ACP) supports the American Academy of Pediatrics' (AAP) 2026 childhood vaccine schedule, which is based on evidence and better reflects current disease epidemiology. The ACP's Immunization Committee found the AAP recommendations to be more evidence-based than the CDC's recommendations, particularly i...
Severe COVID-19, flu facilitate lung cancer months or years later, new research shows
Severe COVID-19 and influenza infections can prime the lungs for cancer development, according to new research. Vaccination, however, largely prevents these changes, suggesting a reduced risk of lung cancer.
Stark divide: Americans more confident in career scientists at US health agencies than leaders
A new survey from the Annenberg Public Policy Center finds that Americans are more confident in career scientists at federal health agencies such as the CDC, NIH, and FDA, than in their leaders. The survey also reveals a significant gap in confidence between career scientists and agency leaders, with only 5% of Americans expressing
ACP advises all adults 75 or older get a protein subunit RSV vaccine
The American College of Physicians advises all adults aged 75 or older to receive a protein subunit Respiratory Syncytial Virus (RSV) vaccine, reducing the risk of severe illness and hospitalization. Adults aged 60-74 with comorbid conditions may also consider receiving the vaccine. The benefits outweigh the harms in this age group.
Native forest litter helps rebuild soil life in post-mining landscapes
Researchers found that adding native forest litter rapidly reshaped soil microbial communities and improved their functional potential. This low-cost strategy could help accelerate ecological recovery in degraded landscapes worldwide.
Upcoming Alliance webinar highlights latest cancer treatment advances
The Alliance for Clinical Trials in Oncology will host a webinar highlighting recent clinical advances in breast cancer, multiple myeloma, and leukemia. Researchers will present key findings from ASH and SABCS meetings, impacting treatment outcomes.
HPV vaccination provides “sustained protection” against cervical cancer
A nationwide study in Sweden found that HPV vaccination significantly reduces the risk of invasive cervical cancer, with sustained protection observed for 13-15 years after vaccination. The study also showed a population-level decline in cervical cancer cases over time.
US newborn hepatitis B virus vaccination rates
A new study found that US newborn hepatitis B virus vaccination rates declined by over 10 percentage points in the last 2 years. This decline reverses 6 years of growth and is aligned with WHO and CDC coverage estimates through 2022.
Missed opportunity to protect pregnant women and newborns: Study shows low vaccination rates among expectant mothers in Norway against COVID-19 and influenza
A study of over 50,000 pregnant women in Norway found low vaccination rates against COVID-19 and influenza, with only 29.9% and 12.1% vaccinated respectively. The study highlights the need for targeted strategies to improve vaccination uptake among expectant mothers.
Novel vaccine protects against C. diff disease and recurrence
A novel vaccination approach cleared harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. The experimental vaccine protected against illness, death, tissue damage and infection recurrence through mucosal immunization.
Booster jabs reduce the risks of COVID-19 deaths, study finds
A new study of over 3 million adults found that booster vaccines reduced the risk of COVID-19-related hospitalization and death. The effectiveness was similar for Moderna and Pfizer-BioNTech booster vaccines, but protection declined over time.
Researchers question editorial bias in COVID-19 vaccine debate
A new commentary raises concerns about editorial bias in scientific publishing, particularly in relation to COVID-19 vaccine safety and efficacy. The authors highlight the rejection of a case report and literature review that raised potential links between mRNA vaccines and rare blood cancers.
Study finds declining perception of safety of COVID-19, flu, and MMR vaccines
A survey by the Annenberg Public Policy Center found that a strong majority of Americans view the MMR vaccine as safe relative to other vaccines. However, the number of people holding this view is below the threshold required for community immunity, which is worrisome.
Building immunity against avian flu risks
A team from UNIGE has shown that certain antibodies to seasonal flu can also target avian flu. Stimulating these antibodies could strengthen protection in the event of a pandemic. Vaccinated individuals show increased levels of cross-reactive antibodies capable of neutralizing the H5N1 virus, which may result in milder symptoms.
Community spread drives ongoing measles transmission in Europe
According to the latest ECDC report, 7,655 measles cases were reported across 30 countries in 2025, with eight fatalities. This represents a significant decrease from 35,000 cases in 2024 but is still almost double the number of cases in 2023.
No association between COVID-vaccine and decrease in childbirth
A study from Linköping University in Sweden found no association between COVID-19 vaccination and decreased childbirth rates. Researchers analyzed data on over 60,000 women and found no statistically significant difference between vaccinated and unvaccinated groups.
Wistar scientists demonstrate first-ever single-shot HIV vaccine neutralization success
Scientists at The Wistar Institute have developed an innovative HIV vaccine candidate that induces neutralizing antibodies against HIV after a single immunization in nonhuman primates. The approach could significantly shorten and simplify HIV vaccination protocols, making them more accessible worldwide.
Estimated effectiveness of 2024-2025 COVID-19 vaccination against severe COVID-19
The study found that 2024-2025 COVID-19 vaccines offer protection against COVID-19 hospitalization and severe in-hospital outcomes. Monitoring vaccine effectiveness remains crucial to guide vaccine composition and recommendations.
Why aren’t more older adults getting flu or COVID-19 shots?
A recent poll found that 42% of people over 50 haven't gotten either flu or COVID-19 vaccines in the past six months. The leading reason for not getting vaccinated was a lack of perceived need, despite clear evidence showing vaccination reduces the risk of serious illness and death in older adults.
Institut Pasteur statement on U.S. administration's attacks against biomedical research, global public health action and vaccination
The US administration's attacks on biomedical research and vaccination policies have severe consequences for healthcare protection and global public health. Certain scientific topics in infectious diseases and immunology have been deprioritized, and the US has withdrawn from major global public health programs.
New platform could develop vaccines faster than ever before
The new platform developed by UVA Health scientists can produce vaccines much faster, cheaper, and more easily than traditional approaches. The platform's proof-of-concept demonstrates its ability to produce highly immunogenic vaccines that can be manufactured at extremely low cost.
Massachusetts closest to eliminating cervical cancer, Southeastern states lag, new study finds
According to a new study, Massachusetts is close to eliminating cervical cancer due to its low incidence rate of 4.3 cases per 100,000 in recent years. In contrast, the Southeast and Southwest regions have higher rates of 11.2 and 9.9 cases per 100,000, respectively, making it challenging for these states to reach elimination goals.
Most would recommend RSV immunizations for older and pregnant people
The CDC recommends RSV vaccination for pregnant women to protect their newborns, while a monoclonal antibody injection is also available for high-risk infants. Most experts agree that RSV immunizations should be recommended for these groups due to the severity of the illness they can cause.
Shingles vaccine linked to slower biological aging in older adults
A new study found that shingles vaccination is associated with lower inflammation, slower epigenetic aging, and overall slower biological aging in older adults. Vaccination showed benefits even four years after the initial dose.
Trends in county-level childhood vaccination exemptions in the US
This study reveals an increase in nonmedical childhood vaccination exemptions from 2010 to 2024, driven by the COVID-19 pandemic, with wide regional disparities.
Maternal vaccine receipt and infant hospital and emergency visits for influenza and pertussis
A study found that maternal vaccinations against influenza and pertussis are associated with reduced hospitalization or emergency department visits in infants under 6 months. Implementing maternal vaccination campaigns can enhance infant health outcomes, addressing low vaccination coverage.
Evaluation of cancer reports following COVID-19 vaccination and infection
A global review of COVID-19 vaccination and infection cases found associations between the two and certain types of cancer. The study analyzed 69 publications and identified potential biological mechanisms, including immune responses and inflammation.
Interim safety of RSVpreF vaccination during pregnancy
A recent study found that the RSVpreF vaccine does not pose a significant risk to pregnant women, providing reassurance for those who wish to be vaccinated. The interim report presents data from a large cohort of pregnancies with vaccine-seeking behavior, and results suggest no notable adverse effects.
Whooping cough vaccination for pregnant women strengthens babies’ immune system
A study by Radboud University Medical Center found that pregnant women vaccinated against whooping cough transfer antibodies to their newborns, which provide long-lasting protection. This discovery supports the World Health Organization's recommendation to maintain whole-cell vaccines in low- and middle-income countries.
CDC urges ‘shared decision-making’ on some childhood vaccines; many unclear about what that means
The CDC recommends shared clinical decision-making for some childhood vaccinations, allowing parents to choose or skip certain vaccines. However, a survey found that many Americans are unclear about what this means and who can be included as health care providers in the discussion.
As measles cases rise, views of MMR vaccine safety and effectiveness -- and willingness to recommend it -- drop
A new survey by the Annenberg Public Policy Center finds a small but significant drop in the proportion of the public that would recommend getting the MMR vaccine, citing concerns over its safety and effectiveness. The survey also shows declines in perceived safety and effectiveness for other vaccines, such as seasonal flu and Covid-19.
Quadrivalent HPV vaccine and high-grade vulvovaginal lesions
A new study found that quadrivalent human papillomavirus (HPV) vaccination is associated with a reduced risk of high-grade vulvovaginal lesions. Expanding HPV vaccination, especially at younger ages, may help prevent these lesions.
Influenza A(H3N2) Subclade K Virus – Threat and Response
The Influenza A(H3N2) subclade K virus is a growing concern due to its antigenic variants and reduced vaccine effectiveness. Researchers emphasize the need for swift responses to protect public health.
Cases of whooping cough remain high, but knowledge about the disease still low
The number of US pertussis cases has surged sixfold since the pandemic began, with over 26,600 reported in 2024. Many Americans are unaware of whooping cough symptoms or that a vaccine exists to prevent it. Despite widespread agreement on the causes and risks of the disease, vaccination rates remain low.
New vaccine could be first to prevent deadly emerging tropical disease
Researchers at Tulane University have developed the first vaccine able to protect nonhuman primates from melioidosis, a long-neglected and deadly tropical disease on the rise. The vaccine uses outer membrane vesicles to trigger a powerful immune response.
New study suggests a way to rejuvenate the immune system
Researchers from MIT and Broad Institute develop temporary 'factory' in the liver to generate T-cell-stimulating signals, boosting immune response to vaccination and cancer immunotherapy treatments. Aged mice showed significant increases in T cell population size and function after treatment.