The study found that 2024-2025 COVID-19 vaccines offer protection against COVID-19 hospitalization and severe in-hospital outcomes. Monitoring vaccine effectiveness remains crucial to guide vaccine composition and recommendations.
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A recent poll found that 42% of people over 50 haven't gotten either flu or COVID-19 vaccines in the past six months. The leading reason for not getting vaccinated was a lack of perceived need, despite clear evidence showing vaccination reduces the risk of serious illness and death in older adults.
Scientists at The Wistar Institute have developed an innovative HIV vaccine candidate that induces neutralizing antibodies against HIV after a single immunization in nonhuman primates. The approach could significantly shorten and simplify HIV vaccination protocols, making them more accessible worldwide.
The US administration's attacks on biomedical research and vaccination policies have severe consequences for healthcare protection and global public health. Certain scientific topics in infectious diseases and immunology have been deprioritized, and the US has withdrawn from major global public health programs.
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The new platform developed by UVA Health scientists can produce vaccines much faster, cheaper, and more easily than traditional approaches. The platform's proof-of-concept demonstrates its ability to produce highly immunogenic vaccines that can be manufactured at extremely low cost.
According to a new study, Massachusetts is close to eliminating cervical cancer due to its low incidence rate of 4.3 cases per 100,000 in recent years. In contrast, the Southeast and Southwest regions have higher rates of 11.2 and 9.9 cases per 100,000, respectively, making it challenging for these states to reach elimination goals.
The CDC recommends RSV vaccination for pregnant women to protect their newborns, while a monoclonal antibody injection is also available for high-risk infants. Most experts agree that RSV immunizations should be recommended for these groups due to the severity of the illness they can cause.
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A new study found that shingles vaccination is associated with lower inflammation, slower epigenetic aging, and overall slower biological aging in older adults. Vaccination showed benefits even four years after the initial dose.
This study reveals an increase in nonmedical childhood vaccination exemptions from 2010 to 2024, driven by the COVID-19 pandemic, with wide regional disparities.
A global review of COVID-19 vaccination and infection cases found associations between the two and certain types of cancer. The study analyzed 69 publications and identified potential biological mechanisms, including immune responses and inflammation.
A recent study found that the RSVpreF vaccine does not pose a significant risk to pregnant women, providing reassurance for those who wish to be vaccinated. The interim report presents data from a large cohort of pregnancies with vaccine-seeking behavior, and results suggest no notable adverse effects.
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A study found that maternal vaccinations against influenza and pertussis are associated with reduced hospitalization or emergency department visits in infants under 6 months. Implementing maternal vaccination campaigns can enhance infant health outcomes, addressing low vaccination coverage.
A study by Radboud University Medical Center found that pregnant women vaccinated against whooping cough transfer antibodies to their newborns, which provide long-lasting protection. This discovery supports the World Health Organization's recommendation to maintain whole-cell vaccines in low- and middle-income countries.
The CDC recommends shared clinical decision-making for some childhood vaccinations, allowing parents to choose or skip certain vaccines. However, a survey found that many Americans are unclear about what this means and who can be included as health care providers in the discussion.
A new survey by the Annenberg Public Policy Center finds a small but significant drop in the proportion of the public that would recommend getting the MMR vaccine, citing concerns over its safety and effectiveness. The survey also shows declines in perceived safety and effectiveness for other vaccines, such as seasonal flu and Covid-19.
The Influenza A(H3N2) subclade K virus is a growing concern due to its antigenic variants and reduced vaccine effectiveness. Researchers emphasize the need for swift responses to protect public health.
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The number of US pertussis cases has surged sixfold since the pandemic began, with over 26,600 reported in 2024. Many Americans are unaware of whooping cough symptoms or that a vaccine exists to prevent it. Despite widespread agreement on the causes and risks of the disease, vaccination rates remain low.
Researchers at Tulane University have developed the first vaccine able to protect nonhuman primates from melioidosis, a long-neglected and deadly tropical disease on the rise. The vaccine uses outer membrane vesicles to trigger a powerful immune response.
A new study found that quadrivalent human papillomavirus (HPV) vaccination is associated with a reduced risk of high-grade vulvovaginal lesions. Expanding HPV vaccination, especially at younger ages, may help prevent these lesions.
Researchers from MIT and Broad Institute develop temporary 'factory' in the liver to generate T-cell-stimulating signals, boosting immune response to vaccination and cancer immunotherapy treatments. Aged mice showed significant increases in T cell population size and function after treatment.
A new white paper by biostatistician Professor Jeffrey S. Morris analyzes the multicomponent US vaccine safety monitoring system, including VAERS and other components. The study suggests improvements to enhance the system's effectiveness and sustain a robust safety monitoring infrastructure.
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This study found that vaccination before and during COVID-19 diagnosis in pregnancy significantly lowers the risk of severe maternal illness and premature birth. The results suggest that COVID-19 vaccination plays a crucial role in protecting pregnant individuals from serious health complications associated with the virus.
A UBC-led study found that COVID-19 vaccination significantly reduces hospitalization, intensive care admission, and preterm birth risks for pregnant women. Vaccination is associated with lower risks even as the virus evolved from Delta to Omicron variants.
A study found that only 6% of FDA-approved drugs reflect the US racial and ethnic makeup, with a decline in Black and Hispanic enrollment between 2021 and 2023. The researchers recommend setting diversity goals at preclinical stages and collecting biological samples to understand how people's bodies react to medications.
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Researchers identified CXCL10 and IFN-gamma as the major drivers of myocarditis in mRNA-vaccine recipients. The two proteins trigger an inflammatory response that damages heart muscle cells, leading to hospitalizations and deaths in severe cases. Most cases recover swiftly with full heart function retained.
A cohort study of adults aged 45 or older with RSV infection found a significant excess risk of cardiovascular events over 1 year, comparable in magnitude to influenza infection. This highlights the importance of RSV as a potential risk factor for cardiovascular morbidity and underscores the need for vaccination to mitigate this burden.
A survey study found that US voters generally support government role in ensuring safe vaccines, with high partisan divide among Trump and Harris supporters. Vaccine requirements for schools show similar support across parties.
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Revising newborn hepatitis B vaccination guidelines may lead to increased perinatal infections, according to infectious disease experts. The study estimates that revoking the policy could result in a significant number of new infections.
A survey of adults in the US found that most people prefer the American Medical Association's (AMA) guidance on vaccine safety over the Centers for Disease Control and Prevention's (CDC), citing concerns about the CDC's recent changes to its website. According to the survey, 35% of Americans would accept the AMA's recommendation, while...
Researchers found that those who received the shingles vaccine were 20% less likely to develop dementia over seven years compared to those who did not receive it. The vaccine was also shown to slow disease progression in those already diagnosed with dementia.
Researchers discovered that pneumococcal vaccination reduced colonization rates of antibiotic-resistant bacteria in children, while rotavirus vaccine showed inconclusive results. Factors such as environmental exposure and yogurt consumption also influenced colonization rates.
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Researchers tested a 'mental model' approach to counter unwarranted fears about mRNA technology. The study found that exposing people to visual models of how vaccines work and/or how cells protect DNA from foreign fragments undercuts the effect of exposure to misconceptions.
Two new Cochrane reviews show that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus. Girls vaccinated before the age of 16 were found to be 80% less likely to develop cervical cancer.
Research published in Contemporary Economic Policy reveals that US cities' indoor vaccine mandates did not significantly increase vaccination rates or reduce COVID-19-related outcomes. The findings challenge assumptions about the effectiveness of local public health interventions.
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A new approach developed by University of Waterloo researchers uses social media posts to identify early warning signs of increasing vaccine skepticism. This method can detect patterns in data much more effectively than traditional methods, providing a bigger lead time before an outbreak occurs.
Rapid rise in early measles vaccination observed in February 2025, ahead of CDC guidelines. The study suggests clinician and parental concern drove increased vaccination rates.
In response to rising RSV cases, ECDC advises policymakers and public health authorities on effective ways to mitigate the impact of RSV disease in infants. Immunisation interventions, including long-acting monoclonal antibodies and maternal vaccines, can prevent severe illness and hospitalization.
Leading experts urge universal hepatitis B vaccination for all newborns in the US, citing a 95% decline in infant infections since 1991. The policy has prevented an estimated one million hospitalizations and 90,000 deaths.
The Phase 3 study demonstrated the safety and non-inferiority of EuTYPH-C Inj.® Multi-dose compared to a World Health Organization (WHO) prequalified comparator TCV, Typbar TCV®. The vaccine was shown to be well-tolerated across all age groups with no serious adverse events.
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A new study found that vaccinated adolescents had a 13% risk of long COVID, compared to 20% among unvaccinated peers. The research suggests that COVID vaccination can help mitigate the risk of long COVID in adolescents and allow them to live their lives normally after infection.
The Annenberg Public Policy Center survey finds that most American adults are unclear about the dangers of measles and the value of vaccination. The survey also shows a decline in support for MMR vaccination among parents, from 90% in November 2024 to 82% in August 2025.
New research published in JAMA Internal Medicine shows that updated COVID-19 vaccines remain effective in preventing severe illness and hospitalizations, with peak protection observed four weeks after vaccination. The study found similar effectiveness against different Omicron subvariants.
A recent study found that patients with advanced lung and skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine. The observation marks a significant step toward a long-awaited universal cancer vaccine to boost tumor-fighting eff...
A recent study found that 90% of people in BC's Lower Mainland have detectable antibodies against measles, indicating high vaccine coverage and population protection. However, the study also found lower immunity rates among older adults, with only 75% of those aged 20-39 having measurable antibodies.
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The National Association of School Nurses reaffirms its commitment to school immunization requirements, citing the life-saving role of vaccines. The updated position statement recommends eliminating vaccine exemptions except in medical contraindications, emphasizing the importance of timely and complete vaccinations.
A Dutch study found that vaccination coverage among children declined faster in households with lower income and those not attending daycare. The study, which analyzed over 2 million children, identified sociodemographic factors contributing to the decline, including parental education and migration background.
Researchers at UMass Amherst have developed a nanoparticle-based vaccine that prevents melanoma, pancreatic and triple-negative breast cancer in mice. The vaccine achieved remarkable survival rates, with up to 88% of vaccinated mice remaining tumor-free.
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A UVA researcher has created a new way to deliver sustained medical treatments using a polymer-based system that assembles itself inside the body. The technology uses hierarchical assembly to create precise, stable structures that hold and release multiple vaccine components over time.
Pertussis in young infants can be life-threatening, with high white blood cell counts and apnea being common symptoms. Vaccination of mothers during pregnancy is critical to protect newborns against this potentially fatal illness.
A new framework for US vaccine policy aims to rebuild trust by acknowledging shared blame, abandoning absolutist tactics, and promoting community-based education. The medical community must own its share of responsibility in addressing declining vaccination rates and rising outbreaks of vaccine-preventable diseases.
A recent survey found that only 38% of US adults recommend taking a Covid-19 vaccine during pregnancy, while only 42% believe it is safe. Women aged 18-49 are even less likely to support vaccination, with 36% and 28% respectively, suggesting a decline in vaccination rates among childbearing women.
A decision analytical model study estimates COVID-19 vaccination during pregnancy will continue to yield meaningful benefits, especially in reducing infant hospitalizations. COVID-19 vaccination has been shown to be safe for pregnant individuals.
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New Cochrane review finds RSV vaccines protect against severe lung infections in high-risk groups. Vaccination with RSV prefusion vaccines reduces lower respiratory tract disease by 77% in older adults, while pregnant people's children benefit from reduced hospitalization risk by 54%.
A study explores barriers to measles vaccination among female healthcare workers in a London hospital. The findings highlight low knowledge of measles and its complications, as well as concerns about the vaccine's link to autism. The article argues that ensuring healthcare workers are aware of their vaccination status, providing better...
A large-scale study in Ohio found measles vaccination coverage to be below the 93% herd immunity threshold, highlighting the need for sustained public health strategies to maintain elimination. The persistent immunity gaps suggest a need for equity-focused approaches.
A new study models the impact of MMR vaccination strategies on measles outbreaks in Texas, highlighting the critical role of improving immunization rates. The findings suggest that increasing vaccine coverage can significantly reduce the risk of large-scale measles outbreaks.
Ensemble projections suggest vaccinating high-risk groups reduces disease burden, while broader vaccine availability saves more lives. Averted COVID-19 burden due to vaccination is robust across immune escape scenarios.
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Scientists found that stretching the skin stimulates immune cells and increases its ability to absorb large molecules, including vaccines. This approach resulted in higher antibody levels against the H1N1 flu antigen compared to traditional needle-free delivery methods.
The report makes recommendations for diagnosing, treating and preventing serious heart and blood vessel complications linked to the virus. Structured cardiac rehabilitation programmes are also recommended to prevent long-term problems after infection and aid recovery from long Covid.
A recent Annenberg Public Policy Center survey found that 70% of the public supports vaccine requirements for MMR in schools. The percentage increased from 63% in August 2023. The survey also showed that over 7 in 10 U.S. adults support a policy making it mandatory for parents to vaccinate their children against preventable diseases.
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