A recent study found that the RSVpreF vaccine does not pose a significant risk to pregnant women, providing reassurance for those who wish to be vaccinated. The interim report presents data from a large cohort of pregnancies with vaccine-seeking behavior, and results suggest no notable adverse effects.
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A study found that maternal vaccinations against influenza and pertussis are associated with reduced hospitalization or emergency department visits in infants under 6 months. Implementing maternal vaccination campaigns can enhance infant health outcomes, addressing low vaccination coverage.
A global review of COVID-19 vaccination and infection cases found associations between the two and certain types of cancer. The study analyzed 69 publications and identified potential biological mechanisms, including immune responses and inflammation.
A study by Radboud University Medical Center found that pregnant women vaccinated against whooping cough transfer antibodies to their newborns, which provide long-lasting protection. This discovery supports the World Health Organization's recommendation to maintain whole-cell vaccines in low- and middle-income countries.
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The CDC recommends shared clinical decision-making for some childhood vaccinations, allowing parents to choose or skip certain vaccines. However, a survey found that many Americans are unclear about what this means and who can be included as health care providers in the discussion.
A new survey by the Annenberg Public Policy Center finds a small but significant drop in the proportion of the public that would recommend getting the MMR vaccine, citing concerns over its safety and effectiveness. The survey also shows declines in perceived safety and effectiveness for other vaccines, such as seasonal flu and Covid-19.
Researchers at Tulane University have developed the first vaccine able to protect nonhuman primates from melioidosis, a long-neglected and deadly tropical disease on the rise. The vaccine uses outer membrane vesicles to trigger a powerful immune response.
A new study found that quadrivalent human papillomavirus (HPV) vaccination is associated with a reduced risk of high-grade vulvovaginal lesions. Expanding HPV vaccination, especially at younger ages, may help prevent these lesions.
The Influenza A(H3N2) subclade K virus is a growing concern due to its antigenic variants and reduced vaccine effectiveness. Researchers emphasize the need for swift responses to protect public health.
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The number of US pertussis cases has surged sixfold since the pandemic began, with over 26,600 reported in 2024. Many Americans are unaware of whooping cough symptoms or that a vaccine exists to prevent it. Despite widespread agreement on the causes and risks of the disease, vaccination rates remain low.
Researchers from MIT and Broad Institute develop temporary 'factory' in the liver to generate T-cell-stimulating signals, boosting immune response to vaccination and cancer immunotherapy treatments. Aged mice showed significant increases in T cell population size and function after treatment.
This study found that vaccination before and during COVID-19 diagnosis in pregnancy significantly lowers the risk of severe maternal illness and premature birth. The results suggest that COVID-19 vaccination plays a crucial role in protecting pregnant individuals from serious health complications associated with the virus.
A UBC-led study found that COVID-19 vaccination significantly reduces hospitalization, intensive care admission, and preterm birth risks for pregnant women. Vaccination is associated with lower risks even as the virus evolved from Delta to Omicron variants.
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A new white paper by biostatistician Professor Jeffrey S. Morris analyzes the multicomponent US vaccine safety monitoring system, including VAERS and other components. The study suggests improvements to enhance the system's effectiveness and sustain a robust safety monitoring infrastructure.
A study found that only 6% of FDA-approved drugs reflect the US racial and ethnic makeup, with a decline in Black and Hispanic enrollment between 2021 and 2023. The researchers recommend setting diversity goals at preclinical stages and collecting biological samples to understand how people's bodies react to medications.
Researchers identified CXCL10 and IFN-gamma as the major drivers of myocarditis in mRNA-vaccine recipients. The two proteins trigger an inflammatory response that damages heart muscle cells, leading to hospitalizations and deaths in severe cases. Most cases recover swiftly with full heart function retained.
A cohort study of adults aged 45 or older with RSV infection found a significant excess risk of cardiovascular events over 1 year, comparable in magnitude to influenza infection. This highlights the importance of RSV as a potential risk factor for cardiovascular morbidity and underscores the need for vaccination to mitigate this burden.
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A survey study found that US voters generally support government role in ensuring safe vaccines, with high partisan divide among Trump and Harris supporters. Vaccine requirements for schools show similar support across parties.
A survey of adults in the US found that most people prefer the American Medical Association's (AMA) guidance on vaccine safety over the Centers for Disease Control and Prevention's (CDC), citing concerns about the CDC's recent changes to its website. According to the survey, 35% of Americans would accept the AMA's recommendation, while...
Revising newborn hepatitis B vaccination guidelines may lead to increased perinatal infections, according to infectious disease experts. The study estimates that revoking the policy could result in a significant number of new infections.
Researchers found that those who received the shingles vaccine were 20% less likely to develop dementia over seven years compared to those who did not receive it. The vaccine was also shown to slow disease progression in those already diagnosed with dementia.
Researchers discovered that pneumococcal vaccination reduced colonization rates of antibiotic-resistant bacteria in children, while rotavirus vaccine showed inconclusive results. Factors such as environmental exposure and yogurt consumption also influenced colonization rates.
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Researchers tested a 'mental model' approach to counter unwarranted fears about mRNA technology. The study found that exposing people to visual models of how vaccines work and/or how cells protect DNA from foreign fragments undercuts the effect of exposure to misconceptions.
Two new Cochrane reviews show that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus. Girls vaccinated before the age of 16 were found to be 80% less likely to develop cervical cancer.
Research published in Contemporary Economic Policy reveals that US cities' indoor vaccine mandates did not significantly increase vaccination rates or reduce COVID-19-related outcomes. The findings challenge assumptions about the effectiveness of local public health interventions.
A new approach developed by University of Waterloo researchers uses social media posts to identify early warning signs of increasing vaccine skepticism. This method can detect patterns in data much more effectively than traditional methods, providing a bigger lead time before an outbreak occurs.
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Rapid rise in early measles vaccination observed in February 2025, ahead of CDC guidelines. The study suggests clinician and parental concern drove increased vaccination rates.
In response to rising RSV cases, ECDC advises policymakers and public health authorities on effective ways to mitigate the impact of RSV disease in infants. Immunisation interventions, including long-acting monoclonal antibodies and maternal vaccines, can prevent severe illness and hospitalization.
Leading experts urge universal hepatitis B vaccination for all newborns in the US, citing a 95% decline in infant infections since 1991. The policy has prevented an estimated one million hospitalizations and 90,000 deaths.
The Phase 3 study demonstrated the safety and non-inferiority of EuTYPH-C Inj.® Multi-dose compared to a World Health Organization (WHO) prequalified comparator TCV, Typbar TCV®. The vaccine was shown to be well-tolerated across all age groups with no serious adverse events.
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A new study found that vaccinated adolescents had a 13% risk of long COVID, compared to 20% among unvaccinated peers. The research suggests that COVID vaccination can help mitigate the risk of long COVID in adolescents and allow them to live their lives normally after infection.
The Annenberg Public Policy Center survey finds that most American adults are unclear about the dangers of measles and the value of vaccination. The survey also shows a decline in support for MMR vaccination among parents, from 90% in November 2024 to 82% in August 2025.
New research published in JAMA Internal Medicine shows that updated COVID-19 vaccines remain effective in preventing severe illness and hospitalizations, with peak protection observed four weeks after vaccination. The study found similar effectiveness against different Omicron subvariants.
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A recent study found that patients with advanced lung and skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine. The observation marks a significant step toward a long-awaited universal cancer vaccine to boost tumor-fighting eff...
A recent study found that 90% of people in BC's Lower Mainland have detectable antibodies against measles, indicating high vaccine coverage and population protection. However, the study also found lower immunity rates among older adults, with only 75% of those aged 20-39 having measurable antibodies.
The National Association of School Nurses reaffirms its commitment to school immunization requirements, citing the life-saving role of vaccines. The updated position statement recommends eliminating vaccine exemptions except in medical contraindications, emphasizing the importance of timely and complete vaccinations.
A Dutch study found that vaccination coverage among children declined faster in households with lower income and those not attending daycare. The study, which analyzed over 2 million children, identified sociodemographic factors contributing to the decline, including parental education and migration background.
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Researchers at UMass Amherst have developed a nanoparticle-based vaccine that prevents melanoma, pancreatic and triple-negative breast cancer in mice. The vaccine achieved remarkable survival rates, with up to 88% of vaccinated mice remaining tumor-free.
A UVA researcher has created a new way to deliver sustained medical treatments using a polymer-based system that assembles itself inside the body. The technology uses hierarchical assembly to create precise, stable structures that hold and release multiple vaccine components over time.
Pertussis in young infants can be life-threatening, with high white blood cell counts and apnea being common symptoms. Vaccination of mothers during pregnancy is critical to protect newborns against this potentially fatal illness.
A new framework for US vaccine policy aims to rebuild trust by acknowledging shared blame, abandoning absolutist tactics, and promoting community-based education. The medical community must own its share of responsibility in addressing declining vaccination rates and rising outbreaks of vaccine-preventable diseases.
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A recent survey found that only 38% of US adults recommend taking a Covid-19 vaccine during pregnancy, while only 42% believe it is safe. Women aged 18-49 are even less likely to support vaccination, with 36% and 28% respectively, suggesting a decline in vaccination rates among childbearing women.
A decision analytical model study estimates COVID-19 vaccination during pregnancy will continue to yield meaningful benefits, especially in reducing infant hospitalizations. COVID-19 vaccination has been shown to be safe for pregnant individuals.
New Cochrane review finds RSV vaccines protect against severe lung infections in high-risk groups. Vaccination with RSV prefusion vaccines reduces lower respiratory tract disease by 77% in older adults, while pregnant people's children benefit from reduced hospitalization risk by 54%.
A study explores barriers to measles vaccination among female healthcare workers in a London hospital. The findings highlight low knowledge of measles and its complications, as well as concerns about the vaccine's link to autism. The article argues that ensuring healthcare workers are aware of their vaccination status, providing better...
A large-scale study in Ohio found measles vaccination coverage to be below the 93% herd immunity threshold, highlighting the need for sustained public health strategies to maintain elimination. The persistent immunity gaps suggest a need for equity-focused approaches.
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A new study models the impact of MMR vaccination strategies on measles outbreaks in Texas, highlighting the critical role of improving immunization rates. The findings suggest that increasing vaccine coverage can significantly reduce the risk of large-scale measles outbreaks.
Ensemble projections suggest vaccinating high-risk groups reduces disease burden, while broader vaccine availability saves more lives. Averted COVID-19 burden due to vaccination is robust across immune escape scenarios.
Scientists found that stretching the skin stimulates immune cells and increases its ability to absorb large molecules, including vaccines. This approach resulted in higher antibody levels against the H1N1 flu antigen compared to traditional needle-free delivery methods.
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The report makes recommendations for diagnosing, treating and preventing serious heart and blood vessel complications linked to the virus. Structured cardiac rehabilitation programmes are also recommended to prevent long-term problems after infection and aid recovery from long Covid.
A recent Annenberg Public Policy Center survey found that 70% of the public supports vaccine requirements for MMR in schools. The percentage increased from 63% in August 2023. The survey also showed that over 7 in 10 U.S. adults support a policy making it mandatory for parents to vaccinate their children against preventable diseases.
Researchers analyzed multiple countries' performance in achieving infection control and economic recovery, highlighting the impact of risk attitudes, patience, and trust on policy decisions. Countries with high levels of trust and patience managed to limit deaths and resuming production, while those with low trust and higher risk toler...
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Researchers found that correcting myths with facts strengthened people's intentions to get vaccinated, making myth-busting strategies a key to broader vaccine distribution. The study suggests three effective strategies for debunking false information about COVID vaccines.
Scientists from La Trobe University and Kumamoto University have identified an internal protein particle hidden within the SARS-CoV-2 virus, which can trigger a strong immune response in killer T cells.
A study published in JAMA found that one shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons. The vaccine reduced the risk of hospitalization by 58% overall, with a higher reduction seen in the first year after vaccination.
A recent study found a sharp increase in hospitalisations for pertussis among children and adolescents in Tuscany, Italy, between 2016 and 2024. The study emphasizes the critical role of timely vaccination administration to prevent further cases and hospitalisations.
A new global systematic literature review and meta-analysis found a significant association between herpes zoster vaccination and reduced risk of heart attack and stroke. Vaccination was linked to an 18% and 16% reduction in cardiovascular events for adults 18 and 50 years old, respectively.
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A comprehensive epidemiological study found that people who had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma and chronic sinusitis. Vaccination against SARS-CoV-2 virus appears to reduce this risk.
A recent study reveals woefully low awareness of human papillomavirus (HPV), the HPV vaccine, and their association with cancer in the Midwestern and Southern US states. These states have seen a rise in HPV-associated cancers, making suboptimal HPV vaccination rates even more alarming.
A new study by Michigan Medicine University of Michigan researchers concludes that broad COVID-19 vaccination in adults saves the US more money than it spends, with significant economic benefits for those over 65 and middle-aged adults. The model focuses on preventing deaths, hospitalizations, and lost productivity.