Research on vaccines and immunization. Covers COVID and flu vaccines, outbreak response, long-lasting antibodies, and vaccination in vulnerable groups.
A new study found that vaccinated adolescents had a 13% risk of long COVID, compared to 20% among unvaccinated peers. The research suggests that COVID vaccination can help mitigate the risk of long COVID in adolescents and allow them to live their lives normally after infection.
The Annenberg Public Policy Center survey finds that most American adults are unclear about the dangers of measles and the value of vaccination. The survey also shows a decline in support for MMR vaccination among parents, from 90% in November 2024 to 82% in August 2025.
New research published in JAMA Internal Medicine shows that updated COVID-19 vaccines remain effective in preventing severe illness and hospitalizations, with peak protection observed four weeks after vaccination. The study found similar effectiveness against different Omicron subvariants.
A recent study found that patients with advanced lung and skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine. The observation marks a significant step toward a long-awaited universal cancer vaccine to boost tumor-fighting eff...
A recent study found that 90% of people in BC's Lower Mainland have detectable antibodies against measles, indicating high vaccine coverage and population protection. However, the study also found lower immunity rates among older adults, with only 75% of those aged 20-39 having measurable antibodies.
The National Association of School Nurses reaffirms its commitment to school immunization requirements, citing the life-saving role of vaccines. The updated position statement recommends eliminating vaccine exemptions except in medical contraindications, emphasizing the importance of timely and complete vaccinations.
A Dutch study found that vaccination coverage among children declined faster in households with lower income and those not attending daycare. The study, which analyzed over 2 million children, identified sociodemographic factors contributing to the decline, including parental education and migration background.
Researchers at UMass Amherst have developed a nanoparticle-based vaccine that prevents melanoma, pancreatic and triple-negative breast cancer in mice. The vaccine achieved remarkable survival rates, with up to 88% of vaccinated mice remaining tumor-free.
A UVA researcher has created a new way to deliver sustained medical treatments using a polymer-based system that assembles itself inside the body. The technology uses hierarchical assembly to create precise, stable structures that hold and release multiple vaccine components over time.
Pertussis in young infants can be life-threatening, with high white blood cell counts and apnea being common symptoms. Vaccination of mothers during pregnancy is critical to protect newborns against this potentially fatal illness.
A new framework for US vaccine policy aims to rebuild trust by acknowledging shared blame, abandoning absolutist tactics, and promoting community-based education. The medical community must own its share of responsibility in addressing declining vaccination rates and rising outbreaks of vaccine-preventable diseases.
A recent survey found that only 38% of US adults recommend taking a Covid-19 vaccine during pregnancy, while only 42% believe it is safe. Women aged 18-49 are even less likely to support vaccination, with 36% and 28% respectively, suggesting a decline in vaccination rates among childbearing women.
A decision analytical model study estimates COVID-19 vaccination during pregnancy will continue to yield meaningful benefits, especially in reducing infant hospitalizations. COVID-19 vaccination has been shown to be safe for pregnant individuals.
New Cochrane review finds RSV vaccines protect against severe lung infections in high-risk groups. Vaccination with RSV prefusion vaccines reduces lower respiratory tract disease by 77% in older adults, while pregnant people's children benefit from reduced hospitalization risk by 54%.
A study explores barriers to measles vaccination among female healthcare workers in a London hospital. The findings highlight low knowledge of measles and its complications, as well as concerns about the vaccine's link to autism. The article argues that ensuring healthcare workers are aware of their vaccination status, providing better...
A large-scale study in Ohio found measles vaccination coverage to be below the 93% herd immunity threshold, highlighting the need for sustained public health strategies to maintain elimination. The persistent immunity gaps suggest a need for equity-focused approaches.
A new study models the impact of MMR vaccination strategies on measles outbreaks in Texas, highlighting the critical role of improving immunization rates. The findings suggest that increasing vaccine coverage can significantly reduce the risk of large-scale measles outbreaks.
Ensemble projections suggest vaccinating high-risk groups reduces disease burden, while broader vaccine availability saves more lives. Averted COVID-19 burden due to vaccination is robust across immune escape scenarios.
Scientists found that stretching the skin stimulates immune cells and increases its ability to absorb large molecules, including vaccines. This approach resulted in higher antibody levels against the H1N1 flu antigen compared to traditional needle-free delivery methods.
The report makes recommendations for diagnosing, treating and preventing serious heart and blood vessel complications linked to the virus. Structured cardiac rehabilitation programmes are also recommended to prevent long-term problems after infection and aid recovery from long Covid.
A recent Annenberg Public Policy Center survey found that 70% of the public supports vaccine requirements for MMR in schools. The percentage increased from 63% in August 2023. The survey also showed that over 7 in 10 U.S. adults support a policy making it mandatory for parents to vaccinate their children against preventable diseases.
Researchers analyzed multiple countries' performance in achieving infection control and economic recovery, highlighting the impact of risk attitudes, patience, and trust on policy decisions. Countries with high levels of trust and patience managed to limit deaths and resuming production, while those with low trust and higher risk toler...
Researchers found that correcting myths with facts strengthened people's intentions to get vaccinated, making myth-busting strategies a key to broader vaccine distribution. The study suggests three effective strategies for debunking false information about COVID vaccines.
Scientists from La Trobe University and Kumamoto University have identified an internal protein particle hidden within the SARS-CoV-2 virus, which can trigger a strong immune response in killer T cells.
A study published in JAMA found that one shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons. The vaccine reduced the risk of hospitalization by 58% overall, with a higher reduction seen in the first year after vaccination.
A recent study found a sharp increase in hospitalisations for pertussis among children and adolescents in Tuscany, Italy, between 2016 and 2024. The study emphasizes the critical role of timely vaccination administration to prevent further cases and hospitalisations.
A new global systematic literature review and meta-analysis found a significant association between herpes zoster vaccination and reduced risk of heart attack and stroke. Vaccination was linked to an 18% and 16% reduction in cardiovascular events for adults 18 and 50 years old, respectively.
A recent study reveals woefully low awareness of human papillomavirus (HPV), the HPV vaccine, and their association with cancer in the Midwestern and Southern US states. These states have seen a rise in HPV-associated cancers, making suboptimal HPV vaccination rates even more alarming.
A comprehensive epidemiological study found that people who had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma and chronic sinusitis. Vaccination against SARS-CoV-2 virus appears to reduce this risk.
A new study by Michigan Medicine University of Michigan researchers concludes that broad COVID-19 vaccination in adults saves the US more money than it spends, with significant economic benefits for those over 65 and middle-aged adults. The model focuses on preventing deaths, hospitalizations, and lost productivity.
Adults with long COVID experience worse work impairment, missed work, and financial distress compared to those without long COVID. Vaccination is associated with improved work outcomes and reduced financial distress among individuals with long COVID.
This book delves into the scientific foundations of mucosal vaccine platforms, discussing immunological mechanisms, novel adjuvants, and real-world development challenges. It serves as a valuable resource for professionals and students in life sciences, immunology, and pharmacology.
A new study found that nearly nine in ten emergency department patients have not received one or more recommended vaccines. This reveals significant gaps in preventive care among underserved populations, who often rely on emergency departments for healthcare.
A national study calls for increased vaccine screening in emergency departments to address health inequities. The study found that nearly a third of the US population lacks primary care access and rarely receives vaccination screenings.
A survey of over 1,600 US adults found that most know the negative impacts of smoking and drinking during pregnancy, but uncertainty exists around vaccines and weight gain recommendations. The majority are unsure about recommended vaccines for pregnant individuals, with a notable drop in knowledge since last year.
Researchers have demonstrated a novel vaccine delivery method using dental floss, which stimulates the production of antibodies in mucosal surfaces, such as the lining of the nose and lungs. This technique has shown superior antibody response compared to current oral vaccination methods.
A nationwide cohort study of 1 million adults found no increased risk of 29 adverse events after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage. The study provides reassuring safety data on the new vaccine, which has been widely adopted in response to the Omicron variant
Researchers at Penn State and WHO develop a method to predict regional measles vaccination coverage even without accurate survey data. The method uses routinely collected data on potential measles cases, resulting in highly correlated predictions with gold-standard DHS data.
Researchers found a significant link between vaccination of pregnant women and a drop in newborns being admitted to hospital with a serious lung infection. The RSV vaccine offered a 72% reduction in hospital admissions, with mothers who received the jab before delivery having twice the protective effect.
This study uses an analytical model to examine the effects of influenza vaccination on both vaccinated and unvaccinated populations. The results show that vaccination provides significant reductions in disease burden, even when vaccine effectiveness is low, but these benefits are limited in high transmission situations.
A review led by Oregon Health & Science University researchers suggests that the US could save $1 billion a year by dropping adult tetanus and diphtheria booster shots if childhood vaccination rates remain strong. The safety of this approach depends on maintaining high childhood vaccination coverage.
A nationwide Danish cohort study found no evidence linking cumulative aluminum exposure from early childhood vaccination to autoimmune, atopic, or neurodevelopmental disorders. The study followed over 1.2 million children and used national health registries to track their aluminum exposure and chronic disorder development.
Researchers found that the H5N1 virus enters the mammary glands through the teat, not via respiratory infection. Lactating cows' self-nursing or mutual-nursing behaviors may facilitate this transmission. Vaccination with two different vaccines showed complete protection against H5N1 infection in cattle.
A Danish study finds that HPV vaccination has reduced prevalence of high-risk HPV types among vaccinated women, suggesting population immunity. However, non-vaccine types remain common and new infections occur more frequently in vaccinated women than unvaccinated women.
A community-based pneumococcal vaccination support program in Sera Town, Japan, reduced pneumonia-related mortality by 25% among the elderly. The program reversed a previously increasing trend in pneumonia mortality rate in the community.
A new ESC Clinical Consensus Statement highlights vaccination as a crucial preventive strategy for reducing cardiovascular events following viral and bacterial infections. Vaccines are recommended for patients with chronic coronary syndromes and heart failure, particularly those at increased risk due to underlying medical conditions.
A new poll by Harvard T.H. Chan School of Public Health and the de Beaumont Foundation found that most U.S. adults (79%) support routine childhood vaccine requirements to attend school, including a majority across party lines. The vast majority of parents and adults believe vaccines are safe for most children.
Despite decades of progress, global immunization targets are unlikely to be met due to stagnant childhood vaccination rates and inequality. The COVID-19 pandemic has further exacerbated the issue, with widespread vaccine misinformation and hesitancy contributing to faltering immunization progress.
Researchers identified six overexpressed and mutated tumor antigens strongly associated with poor prognosis in esophageal cancer. The study's findings suggest BTN2A1, MICA, and HHLA2 as promising targets for anti-ESCA mRNA vaccines.
The University of Texas Health Science Center at San Antonio is targeting hard-to-treat cancers and boosting HPV vaccination rates with a $3.4 million funding from CPRIT. The institution will expand its core facilities laboratories to increase researchers' ability to identify therapeutic targets and develop new cancer technologies.
Researchers found associations between influenza A infection, disrupted gut and nasal microbiomes, and detrimental changes in hippocampal gene expression. Maternal vaccination during pregnancy appeared to offer protection from these changes.
The FDA has recommended pausing the use of a live attenuated chikungunya virus vaccine over concerns about safety. The vaccine was previously approved for emergency use in areas with outbreaks.
A new mRNA vaccine has shown to be more effective and less costly to develop, inducing a robust immune response against SARS-CoV-2 variants. The vaccine's trans-amplifying platform allows for reduced production costs and potential broad protection.
A nationwide decline in MMR vaccination rates among US children was confirmed by a new dataset, with significant variations observed across states and counties. The study provides valuable insights into factors influencing low vaccination rates and can inform targeted strategies to reduce measles outbreaks.
A systematic review found that vaccinating children as early as four months of age for measles could provide sustained protection throughout infancy. However, several barriers exist, including cost-effectiveness and vaccine hesitancy, which need to be addressed to consider an earlier first dose.
A study by researchers at the University of Arizona Health Sciences found that vaccinated people generated an overall protective immune response to Delta and Omicron strains, with slightly fewer antibodies for the mutated parts of the virus. The research suggests that immune changes due to antigenic imprinting may not be a significant ...
Infections from respiratory syncytial virus (RSV) in children requiring primary care led to significant societal economic costs. The study found that the main sources of costs were repeated visits to primary care physicians and parents missing work to care for their sick children, with higher costs for infants under 1 year old.
A recent survey found that over 83% of Americans believe the benefits of the MMR vaccine for children outweigh the risks, despite a current measles outbreak. The survey also showed that vaccination rates are dropping and many people lack knowledge about measles symptoms and prevention.
MIT researchers develop polymer microparticles that release vaccine doses at predetermined times after injection, reducing the need for follow-up shots. The particles showed comparable antibody levels to traditional vaccines in mice, paving the way for potential childhood vaccines with fewer doses.
A national study in Sweden reveals that COVID-19 vaccination levels among older people have become increasingly uneven, with regional and socio-economic differences emerging. The study found lower vaccination rates among certain groups, including those born outside Sweden, men, and individuals with low income and education.