Researchers at Nano Life Science Institute capture real-time footage of estrogen receptor alpha binding to DNA, showing precise gene activation. The study reveals a new model explaining how hormones fine-tune receptor behavior at the DNA level.
A review in Cancer Biology & Medicine explores the potential of AI to decode complex biological data for personalized cancer care. By integrating genomics, medical imaging, and pathology, AI excels at processing vast quantities of genomic and multi-omic data.
Abnormal fungal colonization in pancreatic ductal adenocarcinoma (PDA) promotes tumor growth and activates the host complement system, suggesting Malassezia as a potential driver of cancer development.
A new study from Aalborg University found that removing grades opens up space for different teaching methods, increasing motivation among students. However, the exam- and grade-free environment is only partially being realized, with some students struggling to stay motivated and others benefiting from increased curiosity and engagement.
A University of Houston study reveals that students view engineering and computer science as male-dominated fields, while math and science are seen as more accessible to girls. The researchers call for increased resources to address equity gaps in STEM education.
Researchers developed an LGBTQ Student Support Index to guide universities in promoting inclusivity and support for sexual and gender minority students. The index features 47 items, including policies, facilities, and student support services, and has been found to exhibit sufficient validity and reliability.
A non-invasive self-powered iontophoresis mask based on a water-driven fiber battery has been developed, providing a convenient and portable device for skin care. The mask demonstrated stable performance and improved drug penetration area upon activation by water.
Researchers at Texas A&M University are developing a new method to recover rare earth elements from old electronics, such as tablets and phones, using solid-phase extraction technology. This method aims to reduce energy use, cut down on solvents, and streamline the process, making it more environmentally friendly and commercially viable.
Researchers identified a molecule, fibromodulin, that regulates myofibroblasts at the site of tissue closure to prevent excessive scarring. A peptide drug derived from fibromodulin may help reduce scarring in cleft lip repair and other surgical procedures.
Researchers found that Nd3+ and Sm3+ doping improves Y2-xAxMgTiO6 ceramics' Q* x f value, reaching 74,821 GHz and 67,068 GHz respectively. Doping optimizes properties by balancing chemical bond ionicity, bond energy, and lattice stability.
Researchers discovered people from both income groups experience meaningful nature connections in community gardens, despite lacking nearby greenspace. Community gardens provide habitat, access to nature, and health benefits for people and biodiversity.
Prof Chen brings extensive experience to the role, with a focus on clinically translatable theranostics. He aims to catalyse collaboration and accelerate knowledge exchange in the global nanomedicine community.
Researchers at the University of Sydney have developed protein cages that can package and deliver chemotherapy drugs with greater precision. The technology has the potential to reduce side effects associated with current treatment methods.
The YMCA of Metropolitan Dallas has developed a new pilot program called 'YES YOU CAN!' focusing on brain plasticity and comprehensive support for children, teens, parents, and counselors. The initiative aims to promote well-being and provide access to expert care through virtual and in-person methods.
Researchers at Oregon State University have developed a new chip that consumes half the energy of traditional designs, using AI principles to reduce power consumption for signal processing in data centers. The chip can recover corrupted data more efficiently than conventional systems, which are power-hungry.
Researchers develop technique to make high-dimensional quantum info encoded in light more practical and reliable. This advancement enables the generation and measurement of high-dimensional quantum signals called qudits, which can process and transmit more information securely.
The Lawa model in Thailand has effectively controlled liver fluke infection through a one health approach combining human, animal, and environmental interventions. Over 15 years, the model reduced human infection rates to below 5% and eliminated infections in fish and snail intermediate hosts.
The 2025 Carbon Future Young Investigator Award recognizes young researchers with exceptional research potential and innovative capabilities. Ten recipients received the main award, while 30 others received Honorable Mention Awards for their significant contributions to carbon-related science and technology fields.
Researchers at Nagoya University discovered that combining two tiny vibrating elements can amplify their signal up to 100 million times, enabling the transmission of clear signals over long distances. This finding could innovate long-distance communications and remote medical devices without requiring high energy consumption.
A recent study by Edith Cowan University has found a significant association between excess weight and long-term neurological and mental health symptoms after COVID-19. The researchers suggest that this link could be due to an exaggerated inflammatory response linked to fat tissue, which may store the virus and increase its spread.
A brief spell of talking therapy with a general practitioner reduces symptoms of post-traumatic stress disorder (PTSD) in survivors of critical illness. The effects are modest, but the intervention may help bridge long waiting times between ICU discharge and access to specialist mental health services.
A new report by UCL researchers found that parental genes can influence child development through environmental factors, such as reading habits or access to resources. Non-inherited genes also show a tentative link to mental health traits, with strongest effects around age three.
Researchers at University of East Anglia developed 4D flow MRI scan to diagnose aortic stenosis more accurately and reliably than current ultrasound techniques. The technology offers more accurate measurements of blood flow through heart valves, leading to better prediction of when patients need surgery.
Researchers at the University of Leeds have found that one glacier in Antarctica is rapidly losing ice to its neighboring glacier due to changes in flow direction. This 'ice piracy' effect has been observed over less than 18 years, contrary to previous estimates of hundreds or thousands of years.
According to a study published in The Lancet, nearly one out of five women and one out of seven men aged 20 and older faced sexual violence as a child. The global SVAC prevalence remained high at about 19% for women and almost 15% for men.
A team of researchers has shown that it may be possible to diagnose Parkinson's disease years before it becomes untreatable by scanning people's brains with fMRI. The study used ultra-high field experimental MRI scanners and analyzed brain activity in response to sensory impairments such as loss of smell and visual deficits.
Researchers propose social media redesigns to support different user types, promoting intentional use and improving well-being. The study identifies distinct engagement styles and suggests personalized features to adapt to various user needs.
A study found that removing ovaries and fallopian tubes in women with BRCA1 and BRCA2 genetic variants significantly reduces the risk of early death from cancer. This procedure, known as bilateral salpingo-oophorectomy (BSO), also decreases the risk of developing a second cancer without any serious side effects.
The PEERS for Preschoolers program is an evidence-based solution designed to help young children on the autism spectrum learn fundamental social skills needed to form lasting friendships. The program focuses on key areas such as turn-taking, sharing, cooperative play, and good sportsmanship.
A study published in Neurology found that eating more ultra processed foods may speed up early signs of Parkinson's disease. Participants who consumed over 11 servings of ultra-processed food per day had a higher likelihood of developing three or more early symptoms of the disease.
Scientists have discovered a novel way to enhance the effectiveness of vaccines by boosting stem cell-like memory CD8+ T cells, which can provide decades-long immunity. The study uses mRNA vaccine technology to increase the formation of these cells, offering a promising solution for viruses and cancer therapies.
A new strategy for treating B-cell lymphoma has shown promising results with a next-generation CAR T cell therapy that incorporates IL18. The treatment achieved high remission rates of 81% and complete remission in 52%, with some patients experiencing durable responses lasting two years or more.
Research found that obstructive sleep apnea, especially during REM sleep, is linked to cognitive decline due to damage to the small blood vessels in the brain and downstream impact on memory-related brain regions. Higher oxygen levels during sleep were associated with lower white matter hyperintensities.
A new study uses foot traffic data to enhance neighborhood-level COVID-19 forecasts in New York City. The research reveals how routine activities like dining out and shopping became major transmission pathways, enabling the development of a behavior-driven model that outperforms traditional forecasting methods.
Researchers have identified a link between reduced pulse rate complexity and faster cognitive decline in older adults. The study found that people with more complex heartbeats tend to experience slower cognitive decline over time.
Researchers have developed a novel 23-SNP alpha-1 antitrypsin assay that significantly improves the speed and precision of Alpha-1 Antitrypsin Deficiency (AATD) diagnosis. The test accurately identifies multiple genetic mutations associated with AATD, addressing a long-standing challenge in the medical community.
Janice R. Lachance, a highly respected association executive, has been selected as the new Executive Director and CEO of the American Geophysical Union. She brings a strong intellect, capacity, and commitment to leading the global scientific enterprise into a more sustainable future.
National Jewish Health researchers introduce 'silicosarcoidosis' to describe patients with overlapping features of silicosis and sarcoidosis. The study highlights the need for clinicians to consider occupational exposures when evaluating patients with sarcoidosis-like lung disease.
Researchers at Princeton University uncover a hidden chiral quantum state in KV₃Sb₅, a Kagome lattice topological material. The discovery sheds light on an intense debate within the physics community and expands our understanding of quantum phenomena.
Researchers discovered distinct roles for dopamine receptors in the ventral hippocampus, a region involved in emotions and stress responses. The study highlights the importance of dopamine signaling in anxiety and mood disorders.
A new method using DNA metabarcoding has provided fresh insights into the impact of agriculture on insect biodiversity. The study found a 44% decline in total insect species diversity and a nearly 30% loss of evolutionary diversity in agricultural landscapes.
A study published in Alzheimer's & Dementia found that learning one's Alzheimer's risk can decrease negative emotions like depression and anxiety, but also leads to decreased motivation for maintaining healthy lifestyle changes. Researchers emphasize the importance of personalized disclosure processes to sustain healthy behaviors.
A new UK Multidisciplinary Centre for Neuromorphic Computing will be led by Aston University and funded by EPSRC. The centre aims to develop brain-inspired computing technologies to address digital infrastructure's sustainability challenges, leveraging collaborations with industry partners.
A Washington State University-led team developed a low-cost paper sensor that can rapidly detect personal smoke exposure during wildfires. The sensor, paired with a custom smartphone reader and app, allows users to scan their urine for wildfire biomarkers and quantify their exposure levels in real-time.
A new microscopy method, LICONN, developed by ISTA scientists and Google Research, can reconstruct mammalian brain tissue with all synaptic connections between neurons. This technique uses standard light microscopes and hydrogel to achieve high resolution and opens up possibilities for visualizing complex molecular machinery.
Experts warn of lack of transparency and potential political manipulation with ADM systems, calling for coherent regulation and framework to address concerns. A regulatory foundation is needed to evolve with changing technologies.
A modified surgical face mask can detect chronic kidney disease by analyzing the wearer's breath, showing high sensitivity for CKD-related metabolites. The sensor accurately identifies patients with CKD 84% of the time and those without 88% of the time.
Researchers at Michigan State University found a significant link between problematic social media use and the likelihood of believing fake news. Participants who displayed more symptoms of excessive social media use were more likely to engage with and trust false news.
A camera trapping study reveals India's Ladakh territory is home to the world's highest densities of snow leopards. The research estimated that 68% of India's total population lives in this region, with Hemis National Park having the highest recorded density.
A new study found that collegiate recovery programs with multiple funding sources served twice as many students, providing dedicated space and relapse management support. These programs offer inclusive All Recovery meetings, which provide a welcoming space for students on different recovery journeys to connect and heal.
A study found that bumblebees are twice as likely to visit yellow flowers compared to red ones, with increased scent emission being a key factor. However, the shape of the flowers presented problems for bees, hindering efficient pollen transfer.
Research from the University of Portsmouth suggests that virtual-only clothing could help bridge the gap between fast fashion and environmental sustainability. Consumers with strong appetites for novel experiences are drawn to e-fashion, valuing its creativity, customisability, and interactivity.
The PteridoPortal is an online repository of fern and lycophyte information, allowing researchers to access digitized specimens from 35 herbarium collections. This project has significantly impacted biodiversity research, enabling scientists to inventory species in Colombia and other countries.
Researchers explore the psychological impact of chronic illnesses on patients with asthma and allergies, finding that fear, anxiety, and social stigma can greatly interfere with treatment. The American College of Allergy, Asthma, and Immunology discusses ways clinicians can mitigate these effects and provide better care for patients.
A study on Brazilians in their 50s found that those with hearing loss experienced faster cognitive decline than expected for their age. This highlights the importance of addressing hearing health to prevent dementia, which is a growing concern worldwide.
A team of researchers has outlined a new roadmap for harnessing heterogeneous catalysis to destroy PFAS, which can contaminate water supplies worldwide. The proposed sequential treatment train uses tailored catalytic steps to break down complex PFAS mixtures into harmless by-products.
A study found significant communication barriers in NHS care for patients who are deaf or have hearing loss, with many missing half or more of crucial information. The research team recommends improvements, such as better access to British Sign Language interpreters and accessibility accommodations.
A European research team will explore radiation therapy approaches to improve treatment outcomes and prevent secondary tumors in adolescents and young adults. The KAYAC+ project aims to investigate the clinical results of particle therapy and its impact on cancer development.
Researchers have discovered nearly 35,000 publicly downloadable deepfake image generators, downloaded over 15 million times since late 2022, primarily targeting women. The study highlights the need for robust technical safeguards and regulatory approaches to address the creation and distribution of these harmful AI models.
Roman Space Telescope successfully completes thermal vacuum test to ensure precise instrument temperatures. The telescope is set to connect major parts in November and complete final tests by the end of the year.
A new study from the University of Surrey explores how metaverse platforms like Roblox and ZEPETO are changing consumer engagement forever. Digital doppelgängers, using AR and VR technologies, create immersive experiences that enhance brand engagement and emotional connections.
A recent study found that situational or state curiosity may increase across the lifespan, particularly in older adults. This type of curiosity has been linked to improved well-being and cognitive outcomes in older age.
A new study reveals that magnetar flares could be a potential source of heavy elements in the universe. By analyzing archival data and observations of magnetar flare events, researchers estimate that up to 10% of heavy elements like gold, uranium, and platinum may come from these cosmic explosions.
Proof scores use term rewriting to verify system properties, striking a balance between automation and human effort. Despite limitations, the technique has been successfully applied to various systems and protocols, with potential for critical applications in safety-critical systems.
The PEARL trial found that low-dose rapamycin improved lean muscle mass and reduced pain in women, while also showing improvements in emotional well-being. The study suggests rapamycin may offer measurable benefits for physical function and overall well-being in older adults.
Manuel Souto received the Young Researcher Award from the Spanish Royal Society of Chemistry for his leadership of the ElectroMolMat research group at CiQUS. The award recognizes his outstanding professional achievements and contributions to electroactive molecular materials.
Scientists at Oak Ridge National Laboratory developed a novel vacuum-assisted extrusion method to reduce internal porosity in large-scale 3D-printed polymer parts by up to 75%. This innovation enables the production of stronger and more durable components for aerospace, automotive, and defense industries.
Researchers at RMIT University developed a sponge-like device that captures water from the atmosphere and releases it in a cup using solar energy. The device remained effective across a broad range of humidity levels and temperatures, demonstrating its potential for off-grid water harvesting systems.
A new study reveals lysine-specific demethylase 1 (LSD1) as a crucial player in oral squamous cell carcinoma (OSCC) initiation. Inhibiting LSD1 in early-stage lesions prevents tumor growth, restores immune function, and halts OSCC progression.
A recent study on Reddit climate change discussions found that only 1 in 25 links are from scientific sources, highlighting the lack of science-based debate on the platform. The study also highlighted the dominance of mass media and social media sources, which often spread misinformation.
Researchers mapped the human sweet taste receptor's 3D structure in unprecedented detail, revealing its binding pocket and shedding light on why people differ in their sensitivity to sweets. This breakthrough could lead to the discovery of new regulators to curb sugar cravings.
Researchers found that individuals with excessive and dependent social media use are more likely to engage with and believe false information. The study suggests that social media addiction may lead to increased susceptibility to misinformation.
A new study reveals the atmosphere can store moisture over extended periods, creating a physical memory effect. This 'memory' allows monsoon systems to flip between two stable states, with severe consequences for regions relying on monsoon rainfall.
GigaScience Press has won the first-ever Crossref Metadata Award, recognizing its efforts in providing high-quality metadata for its journal GigaByte. The award highlights the press's commitment to making research more discoverable and accessible through rich metadata standards.
A study found that losing a parent increases the risk of bullying among female children, adolescents, and those in rural areas. The researchers hope this data informs tailored support for bereaved youth. Effective interventions should address emotional and social dimensions of support, fostering inclusive environments.
Researchers at Texas A&M University and the University of Georgia are working on interventions to impact both canine and human health. The study combines field and laboratory research, treating dogs, measuring clinical outcomes, and studying ecological factors to advance Chagas disease research.
A study published in JAMA Neurology found no evidence supporting a diagnosis of the New Brunswick neurological syndrome of unknown cause, highlighting the need for independent clinical evaluations. The data revealed presence of several neurodegenerative and non-neurodegenerative conditions instead
Paul Mulhausen, MD, will lead the American Geriatrics Society (AGS) in advancing healthcare for older adults. The AGS has elected Mulhausen as its new President following his extensive experience in clinical care, medical education, and policy advocacy.
A new study by Yale University researchers found significant differences in life expectancy among US states and Washington, D.C. over the past century, with some states experiencing dramatic gains while others saw little to no improvement. The study used an age-period-cohort model to analyze mortality trends and found that systemic fac...
Researchers have identified where and when the most aggressive subgroups of childhood brain tumors develop, revealing that they arise from precursor cells of highly specialized nerve cells. The study suggests that genetic changes occur many years before clinical symptoms appear, paving the way for possible early detection methods.
Scientists at Boston Children's Hospital discovered that native nucleosomes contain a physical code governing their role in genome architecture. This insight could lead to new understanding of the maintenance of cellular function and the development of diseases like autoimmunity and cancer.
Researchers developed iron carbide catalysts for deoxygenative C-C coupling of benzyl alcohols, producing bibenzyls and leveraging the Fischer-Tropsch synthesis process. The system promotes radical reaction pathways and accelerates oxygen removal on the catalyst surface.
Researchers identified the thalamocortical pathway as the key area modified during learning, which physically changes links between brain regions. Learning refines the conversation between the thalamus and cortex at a cellular level, making it faster, stronger, and more precise.
A new study reveals that over half of Black and Latina women reported using personal care products with formaldehyde-releasing preservatives, highlighting critical safety gaps in product regulation. The study found that these chemicals are present in a wide range of products, including shampoo, lotions, and eyelash glue.
A new £5 million project will tackle fundamental questions in solar physics by simulating the Sun's radiation and atmospheric conditions. The Solar Atmospheric Modelling Suite (SAMS) aims to build a next-generation modelling tool for the solar atmosphere, capturing its complex dynamics.
A groundbreaking study estimates that only a minuscule fraction of the deep seafloor has been imaged, with less than 0.001% of the ocean floor having visual records. This limited exploration is largely due to high costs and geographical bias in ocean exploration efforts.
A study of 200 mpox social media memes found that 4 in 10 contained misinformation or stigmatized minority groups, despite most promoting awareness and education. The majority of memes were accurate and informative, highlighting the need for responsible online content creation.
Researchers at UiT The Arctic University of Norway discovered Staphylococcus borealis, a previously unknown bacterium resistant to several antibiotic classes. The study found that S. borealis can cause urinary tract infections and inflammation around implants in individuals with weakened immune systems.
A study published in PLOS One suggests that curiosity and interest in lifelong learning can help offset or prevent Alzheimer's disease. Researchers found that state curiosity, which is a momentary feeling of curiosity when asked about specific topics, increased sharply after middle age and continued well into old age. This contrasts wi...
A randomized clinical trial with 30 female participants found that neither hot nor cold water immersion improved muscle recovery from exercise-induced damage. Despite physiological differences between groups, none showed significant improvements in muscle soreness or swelling.
Today's children will endure more climate extremes than any previous generation due to continued greenhouse gas emissions. The study highlights the social injustice of climate change and its impacts, with the most vulnerable children facing almost all, or nearly all, unprecedented exposure to heatwaves in their lifetime.
A randomized controlled trial in Switzerland found that legal access to cannabis decreases problematic consumption, especially among individuals using other substances. After two years, participants showed significant improvements in mental state.
The 4th Annual MPS World Summit brings together over 1,500 international experts to explore advancements in Microphysiological Systems (MPS) research. This event focuses on drug and chemical safety, disease modeling, and regulatory testing.
A new study reveals that SIRT5 promotes BMP9-induced osteogenic differentiation by stabilizing HIF-1α. The research suggests targeting SIRT5 could enhance bone regeneration and is a promising approach for clinical applications.
The study provides an overview of the fruit fly connectome, enabling scientists to intelligently design experiments to investigate individual neurons or circuits. Sex-specific differences were identified between male and female specimens, shedding light on behavioural differences such as egg-laying and mating.
A six-year US longitudinal study suggests that religious and spiritual engagement are associated with better physical health outcomes. The research found no evidence to support the notion that religion or spirituality leads to improved physical well-being.
Xu Zhangrun, a prominent Chinese legal scholar, has received the Human Rights Award from Friedrich-Alexander-Universität Erlangen-Nürnberg for his advocacy of democracy, academic freedom, and freedom of expression. The award is a recognition of his tireless efforts to challenge autocratic injustice in China.
A new research published in Frontiers of Computer Science proposes a Multi-Projection Recurrent (MPR) model for hypernym detection and discovery. The MPR model addresses polysemy by leveraging multiple projection functions, allowing it to handle multiple hypernyms at the same semantic level.
Researchers propose a configuration design method for mega constellations in Low Earth Orbit (LEO) using basic and accompanying satellites. The method considers satellite imaging width, formation flying of subgroup satellites, and global uniform coverage by payloads to optimize constellation configuration. By solving nonlinear optimiza...
STN-DBS treatment modifies the extracellular space (ECS) by increasing hyaluronic acid content, EAAT2 expression, and reducing extracellular glutamate concentration. This study demonstrates that STN-DBS enhances ISF drainage by restoring AQP-4 expression while decreasing α-synuclein levels.
This study finds that teen drivers in older vehicles are more likely to be involved in fatal crashes, highlighting the need for safer vehicles. The study's authors stress the importance of ensuring teens drive newer vehicles equipped with advanced driver assistance technologies.
A new study finds that macrophages, the liver's cleanup specialists, quickly adapt after injury to clear debris and support tissue recovery. The research highlights the dynamic nature of these cells during liver injury and repair, offering promising implications for future therapies.
A 10-year study confirms a one-week course of post-surgery radiotherapy is just as safe and effective as the traditional three-week regimen for early-stage breast cancer patients. This shorter schedule provides similar cancer control without additional long-term side effects.
A meta-analysis reveals significant racial and ethnic disparities in the reporting of race and ethnicity in clinical trials for pharmacotherapy of mental disorders. The study underscores the importance of equitable recruitment and reporting in clinical trials to ensure inclusive representation of diverse populations.
Scientists at the University of Southern California have developed a wearable lactation pad that monitors breast milk for safe levels of acetaminophen. The device provides real-time information, enabling parents to make informed decisions about breastfeeding and medication use, and may also be adapted to detect other drugs and biomarkers.
A study among 2,272 mother-child pairs found that infants whose mothers consumed fresh avocado during pregnancy had a 44% lower risk of developing food allergies at 12 months. Avocado intake was associated with improved maternal and infant health outcomes, including breastfeeding duration and diet quality.
Researchers have developed a synthetic lichen system that enables concrete to heal itself without external intervention. This innovation has far-reaching potential in reducing maintenance costs and extending the longevity of concrete infrastructure.
A new study published in Genes & Diseases journal introduces a novel therapeutic approach for acute myeloid leukemia (AML) using the METTL3 degrader ZW27941. The research team found that ZW27941 exhibited potent anti-leukemic activity and synergistic effects with existing AML therapies.
A new study reveals that comb jellies and other ancient animals evolved the ability to control genes from far away, over tens of thousands of DNA letters, around 650-700 million years ago. This discovery sheds light on the fundamental principles of genomic regulation that govern our cells and bodies today.
Small drones combined with free software can calculate and monitor carbon in community forest organisations. The research results show that these measurements are comparable to those derived from field-based measurements.
A meta-analysis of over 140,000 participants found a significant association between excess weight and neurological/neuropsychiatric symptoms in post-COVID-19 condition. The study suggests that maintaining a healthy weight may be crucial in mitigating these symptoms.
Researchers developed an intelligent autonomous robot capable of automating hospital disinfection processes through dual disinfection system, increasing efficiency and precision. The robot's performance was validated through real-world testing, reducing the risk of infection in hospitals.
A synthetic lichen system developed by Texas A&M researchers enables concrete to heal itself without outside intervention. This innovation uses cyanobacteria and filamentous fungi to produce crack-filling minerals, setting it apart from previous self-healing concrete endeavors.
A portable device can instantly detect dangerous street drugs at extremely low concentrations, highlighting their dangers. The device, being trialled by drug-checking services in the UK, Norway, and New Zealand, allows for cheap and on-the-spot analysis of substances.
Researchers found that NFL players are 3.7 times more likely to suffer a tear of the extensor mechanism during a short rest week than a long rest week or resting less than seven days.
Researchers at MIT have captured the first images of individual atoms freely interacting in space, visualizing never-before-seen quantum phenomena. The technique allows scientists to directly observe correlations among 'bosons' and fermions, shedding light on their behavior and interactions.
A University of California, Riverside-led research team adapted an intervention for childhood obesity prevention to better serve Latina mothers, non-maternal caregivers, and families of low-income backgrounds. The study emphasizes the importance of involving non-maternal caregivers in the adaptation process.
Researchers developed a thermal sensor to measure phonon vibrations at a molecular scale, finding that certain pathways cause destructive interference to reduce heat flow. This discovery could lead to the development of new materials and electronics with improved heat dissipation and efficiency.
A global study reveals a consistent gap in trust toward climate scientists based on political ideology, with right-leaning individuals reporting lower trust. The divide is strongest in wealthier democracies and English-speaking nations.
Researchers have discovered that combining antibiotics with an enzyme called endolysin can protect against infection by resistant bacteria in all bodily organs, including the brain. This breakthrough could lead to a new treatment for meningitis, a life-threatening disease caused by resistant bacteria.
Scientists have discovered a Triassic-era fossil with an elongated jaw structure, similar to modern-day pike and needlefish. The findings suggest that different species independently evolved similar jaws hundreds of millions of years apart, highlighting the universal problem-solving strategies in nature.
A groundbreaking study by Washington University in St. Louis found that eating disorders affect all racial groups equally among college students. The study revealed that up to 13% of respondents showed signs of eating disorders, with bulimia nervosa and binge eating disorder being the most common types.
Researchers explored combining checkpoint blockade therapy with in situ vaccination to improve anti-tumor immunity in colorectal cancer. This innovative approach aims to mitigate adverse effects and enhance treatment effectiveness by targeting immune checkpoints and promoting tumor-specific T cell responses.
A systematic review of 46 clinical studies with 4,113 participants found that automated insulin delivery (AID) systems improved time in target range and reduced elevated glucose values compared to conventional pump therapy. However, low efficacy was observed during periods with very low glucose levels.
A new study suggests that collaborating with human radiologists and using AI for initial screenings can streamline the process, reducing costs by up to 30%. This delegation strategy leverages AI's strengths in identifying low-risk cases while allowing humans to focus on complex or ambiguous ones.
A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.
A new study suggests that urban agriculture alone can only feed about one fifth of a city's population, but combining it with near-urban farming can ensure food security for the entire city. Peas are found to be the best crop for maximizing protein and calories while minimizing land requirements in normal climate scenarios.
Researchers developed an artificial interphase using Al-Li/LiF to solve the lithium metal battery's volume expansion issue. The study shows a discharge capacity of 114.3 mAh·g after 300 cycles, demonstrating improved cycle stability and capacity retention.
Researchers identified a genetic mutation in Turkish Pointers that distinguishes their forked nose, linking it to cases of human orofacial clefts. The study suggests that the mutation of PDFGRA gene may be involved in some cases of human orofacial clefts.
A major global review of bird flu in cats found 607 cases, including 302 deaths, from 18 countries and 12 cat species. The virus is highly infectious and can spread through direct contact with infected birds or other mammals, leading to severe symptoms like brain swelling.
The MASTER project invites educational institutions to develop innovative XR educational content and validate cutting-edge XR technologies in real settings. Selected applicants will receive financial support, access to advanced XR tools, and expert mentorship.
City of Hope experts will present new cancer treatment approaches, targeted therapies and lifestyle changes aimed at reducing cancer risk and improving survival. Highlights include discussions on biomarkers in kidney cancer, symptom science and palliative care.
Researchers develop new method to simulate Pockels effect, a key phenomenon in optoelectronics, using Density Functional Theory and finite differences. The approach enables accurate modeling of barium titanate's behavior, paving the way for more efficient devices.
A new study by Mass General Brigham researchers has identified a natural 'brake' within the innate immune system that can prevent organ transplant rejection. The discovery highlights a promising target for new therapies and offers hope for longer-lasting transplant success and reduced need for lifelong immunosuppression.
A Canadian study found a strong association between ultra-processed food consumption and cardiometabolic risk factors, including high blood pressure and diabetes. Individuals who consumed the most ultra-processed foods had higher BMI, waist circumference, and blood pressure levels than those who consumed fewer or no such foods.
African starlings form reciprocal helping relationships that last over many years, similar to human friendships. The birds preferentially aid relatives but also help specific non-relatives, suggesting a complex social structure.
Scientists have developed a universal protocol to investigate how viruses interact with host cells, revealing a cascade of cellular reactions triggered by contact between the virus and cell surface. This breakthrough provides insights into the biology of influenza viruses and identifies potential targets for antiviral therapies.
Researchers analyzed the genetic information of over 70,000 infants to discover 11 genetic markers that influence when babies take their first steps. This study suggests that genetics plays a significant role in determining when children start walking, with some kids naturally starting earlier or later due to their genetic propensity.
A study by Oregon State University finds that human-caused climate change led to 15,000 extra deaths from wildfire PM2.5 in the continental US between 2006 and 2020. The economic burden associated with these deaths is estimated at $160 billion annually.
Insilico Medicine will present detailed Phase IIa data on rentosertib, a novel TNIK inhibitor developed using generative AI, for the treatment of idiopathic pulmonary fibrosis (IPF). The company has previously demonstrated encouraging results from its Phase IIa study, showing favorable safety and tolerability across all dose levels.
Researchers identified six risk groups for cardiometabolic complications in older people without type 2 diabetes, with a special high-risk group characterized by inflammation and insulin resistance. The study emphasizes the need for precise early detection and prevention strategies.
Researchers at Nationwide Children's Hospital found that teen drivers in vehicles 6-15 years old and those with fewer driver assistance technologies had a higher risk of death in fatal crashes. The study also showed that driving newer vehicles can reduce the risk of fatal crashes for teen drivers.
A new study found that only 39% of clinical trials report the race or ethnicity of participants involved. The research highlights the need for more comprehensive reporting and recruitment practices to ensure studies better reflect diverse populations globally. This is crucial for developing inclusive, effective, and equitable treatments.
A new study confirms that the Bergen 4-Day Treatment (B4DT) is effective in treating panic disorder, with patients reporting significant improvement weeks after treatment. Long-term follow-up studies show that the treatment's benefits persist and even increase over time, reducing symptoms of anxiety and depression.
Researchers found that MCT4 inhibition up-regulates genes involved in triglyceride and fatty acid synthesis, increasing intracellular lipid accumulation. Overexpression of MCT4 reduces lipid accumulation by down-regulating hepatic lipid metabolism-related genes.
A study by FAU Harbor Branch found fewer parasites in the Indian River Lagoon, indicating a disrupted food web and simplified ecosystem. This scarcity suggests environmental stressors like pollution and habitat loss have reduced parasite presence.
The Society for Healthcare Epidemiology of America strongly urges CDC to reinstate HICPAC due to its critical role in providing evidence-based guidance on infection control practices. Disbanding the committee jeopardizes decades of progress in preventing healthcare-associated infections, putting patients at risk and creating uncertaint...
A new study by University of California San Diego researchers found that the SARS-CoV-2 virus emerged in humans via wildlife trade, not a lab leak. The viruses most closely related to SARS-CoV-1 and SARS-CoV-2 were found in palm civets and raccoon dogs in southern China.
The Singapore-MIT Alliance for Research and Technology has launched the Wafer-scale Integrated Sensing Devices based on Optoelectronic Metasurfaces (WISDOM) research group, focusing on developing ultra-thin sensing devices for machines to perceive depth and spatial detail like human vision. This multi-million-dollar program aims to adv...
A study published in Contemporary Economic Policy found that adoption of vertical identification laws has not reduced teenage drinking and smoking. The analysis of 1991-2019 data from the Youth Risk Behavior Surveys revealed no statistically significant or economically important effect on these behaviors.
A new study from the University of Kansas found that providing pre-service teachers with a low-stakes setting to teach difficult topics, such as the Holocaust, improves their confidence. The research involved four novice educators who delivered lessons on the book 'Night' by Elie Wiesel in a mixed-reality simulated classroom.
A recent study published in Osteoarthritis and Cartilage reveals that obesity is a leading cause of knee osteoarthritis. The research also found that certain lifestyle changes, such as following a Mediterranean diet and engaging in regular physical activity, can significantly reduce the risk of developing the condition.
Alzheimer's disease and other dementias are rising rapidly in China due to population growth and high-risk factors like high blood sugar, smoking, and obesity. The study projects continued rise unless effective interventions are implemented.
Researchers found that invasive brown widow spiders effectively defend their egg sacs against wasp parasites through multiple defence strategies. By constructing denser spikes on their egg sacs and using guarding behaviors, the spiders protect themselves against high levels of predation and parasitism.
The latest focus issue of Molecular Plant-Microbe Interactions explores the molecular, cellular, and genomic details of cereal crop diseases, highlighting key research on plant-pathogen interactions. Groundbreaking work has advanced the field, offering new insights into disease resistance and management strategies.
A new study reveals that exosomal lnc-TAF12–2:1 promotes bladder cancer progression through the miR-7847–3p/ASB12 regulatory axis. Silencing of lnc-TAF12–2:1 inhibited tumor growth and induced apoptosis, while its overexpression enhanced cell proliferation and migration.
A clinical trial finds that moxidectin is more effective than current treatment ivermectin for lymphatic filariasis, a disease affecting millions in Africa. Moxidectin has a persistent effect and may require fewer rounds of treatment, potentially accelerating its elimination.
A study by King's College London reveals how surveillance technologies in smart homes exacerbate power imbalances between domestic workers and employers, undermining their rights and increasing vulnerability. The constant monitoring of these employees can lead to mental wellbeing issues and a lack of trust in the workplace.
A novel AI model developed by researchers at Mount Sinai improved delirium detection by quadrupling the rate of identification and treatment in hospitalized patients. The model accurately calculates delirium risk in real-time and integrates smoothly into clinical workflows, helping staff catch and treat more patients with delirium.
The IQWiG event explores assessment criteria and potential applications of registry data in regulatory research. Experts share experiences working with observational data to discuss its trustworthiness and credibility.
The study found that mRNA-1083 induced higher immune responses than standard care influenza and COVID-19 vaccines, with an acceptable tolerability and safety profile. The vaccine met noninferiority criteria for all 4 influenza strains and SARS-CoV-2 across various age groups.
Scientists develop a new class of small molecules that activate ferroptosis, a process triggering cell death in cancer cells with high metastatic potential. These molecules show promise in treating breast, pancreatic, and sarcoma cancers resistant to standard chemotherapy.
The ESMO Breast Cancer 2025 congress will cover topics such as circulating tumour DNA, immunotherapies, and emerging therapies for managing breast cancer. The event will feature key findings on predictive biomarkers, ctDNA, and tumour-infiltrating lymphocytes.
A new approach targeting inflammation may help prevent or slow the progression of Type 1 diabetes by blocking TYK2 protein signaling. Researchers found that inhibiting this protein reduced harmful inflammation in the pancreas and protected insulin-producing beta cells.
The MEDiCS project, led by Prof. José Luis Mascareñas, aims to develop a new anticancer agent targeting cancer stem cells using ruthenium-based metallic complexes. The €2.5 million funded project will progress the technology through preclinical phase and human clinical trials for pancreatic and colon cancers.
Increasing Klotho protein levels in mice extends lifespan and improves both physical and cognitive health when aging. The treatment also enhances muscle, bone, and cognitive health, with potential benefits for osteoporosis prevention and brain function.
Researchers have developed a model called Difface that can reconstruct 3D facial images from DNA data, improving forensic investigations. The method demonstrates excellent performance in aligning and reconstructing facial images from paired DNA differences.
Research published in Global Change Biology found that tiger presence is associated with higher forest vegetation carbon stocks, lower carbon dioxide emissions, and higher carbon dioxide removal. Tiger density also seems to have a guardian effect to protect forests from deforestation and associated carbon emissions.
A national survey found that 1,888 out of 7,332 women reported experiencing words, gestures, or attitudes that shocked or offended healthcare professionals. Disrespectful care was more common among nulliparous women, those with high education levels and birth plans, and those who breastfed.
A new study published in Nature Climate Change reveals that the world's wealthiest 10% are responsible for two thirds of observed global warming since 1990. The top 1% of the wealthiest individuals globally contributed 26 times the global average to increases in monthly 1-in-100-year heat extremes globally.
The research mapped air pollution levels and carbon dioxide emissions in over 13,000 urban areas globally, highlighting regional disparities and progress towards cleaner air. Urban areas with aggressive environmental policies saw simultaneous declines in all pollutants.
Two new predictive algorithms use health data and blood tests to identify high-risk patients, offering improved accuracy in diagnosing cancers. The models identified additional medical conditions associated with increased cancer risk and new symptoms indicative of multiple cancer types.
A study published in the Journal of Internal Medicine found that individuals with Down syndrome have a higher risk of age-related cardiovascular diseases, particularly ischemic stroke and hemorrhagic stroke. The researchers also noted an increased risk of heart attack in young people with Down syndrome.
Scientists have discovered a mechanism that controls tomato ripening, regulated by autophagy, which also affects life- and health-span in humans and animals. This finding has significant implications for reducing food waste and addressing sustainable food security.
A major study found that taking the progesterone-only pill can increase asthma attacks in some women, especially those under 35 and using fewer asthma treatments. Women with eosinophilic asthma were also at a higher risk. The research aims to better understand why women are more likely to have severe asthma than men.
Researchers at Linköping University developed a miniaturized iontronic micropipette to precisely modulate neuronal and astrocytic activity. The study revealed dynamic dynamics between cells, highlighting the importance of chemical signaling in brain function.
Researchers found that people are more willing to empathize with groups (53%) than individuals (34%), even though both tasks were equally difficult and distressing. This may be due to the additional context information provided by group images, which makes empathizing feel easier by comparison.
A Korean research team developed a high-performance proton exchange membrane for electrochemical LOHC hydrogen storage, reducing toluene permeability by over 60%. The new membrane improved Faradaic efficiency to 72.8% and reduced voltage degradation rate in long-term operation.
Researchers have developed a new 'pressurised spinning' innovation to create cellulose materials from cow manure, a waste product in the dairy farming industry. This process is an energy-efficient example of circular economy and has significant environmental and commercial benefits.
A new scoping review confirmed the lack of research on managing menopause symptoms in women with serious mental illnesses. The study suggests that psychoeducation programs are essential to support these women during the menopause transition.
A new study found that cannabis-related hospital visits increased by 20% in Arizona between 2016 and 2021, with nearly eight times more patients having a primary diagnosis of a mental health disorder. The study suggests easier access to cannabis may be partly responsible for the trend.