The Stockholm Declaration on Chemistry for the Future emphasizes the need to integrate health and sustainability in chemical products and processes. It calls for action from scientists, industry, educators, students, and policymakers to collaborate on implementing solutions that balance human well-being with environmental protection.
Researchers developed a new method for extracting and identifying proteins from ancient soft tissues, providing insights into past lives and diseases. The technique identified over 1,200 ancient proteins from 2.5mg of sample, offering a window on human history.
Researchers from Mayo Clinic Comprehensive Cancer Center will present practice-changing studies on chemotherapy approaches, AI applications in oncology, and new therapies for breast and melanoma. The event will feature 59 abstracts highlighting advancements in cancer care.
A cohort study found that lower-than-recommended lead levels were associated with worse academic grades, suggesting the need to reconsider current blood lead reference values for further interventions. The findings support lowering these values to improve outcomes for children and adolescents.
A team of physicists has developed a new quantum sensor that can detect vectorial magnetic fields with large dynamic range and multi-axis capabilities. The sensor is based on spin defects in hexagonal boron nitride, a two-dimensional material that offers new degrees of freedom compared to existing nanoscale sensors.
Forest-based agroforestry (FAF) can support forest health and biodiversity, enhance carbon sequestration and storage, generate economic benefits for local communities, and aligns with Indigenous land stewardship practices. The study recommends explicit inclusion of FAF in agroforestry policies to maximize climate benefits.
Researchers found that intestinal bacteria and their metabolites can accelerate blood vessel aging and trigger cardiovascular disease. The breakdown product of phenylalanine, phenylacetic acid, accumulates with age and leads to senescence of endothelial cells.
Exposure to lingering fine particulate matter from wildfire smoke was associated with increased hospitalization risks for various cardiorespiratory conditions, including ischemic heart disease and respiratory diseases. The study's findings highlight the need for research into the long-term health impacts of wildfire smoke.
A new machine learning tool called GLUCOSE helps doctors manage blood sugar levels in patients recovering from heart surgery by recommending tailored insulin doses. The model outperformed experienced clinicians in keeping blood sugar levels within a safe range, despite using only current patient data.
Emerging imaging technologies like Tomosynthesis, Contrast-Enhanced Spectral Mammography, and Molecular Breast Imaging improve detection of high-risk populations and dense breast tissue. AI Integration, Noninvasive Biomarkers, and Hybrid Techniques hold promise for reducing radiation risks and overdiagnosis.
The foundation recognizes five early-career scientists who apply computational methods to cancer research, with a focus on developing new protein designs and understanding chromatin modifications. Their work aims to improve treatment strategies and precision oncology for various cancers.
A team of astronomers from ICRAR discovered a new type of cosmic phenomenon called ASKAP J1832-0911, which emits pulses of radio waves and X-rays for two minutes every 44 minutes. This is the first time such an object has been detected in X-rays.
A team of palaeontologists from Fundación Dinópolis has discovered a partial stegosaurian skull in Spain, revealing previously unknown aspects of the species' anatomy. The find has led to the proposal of a new evolutionary hypothesis and the definition of a new group called Neostegosauria.
The Physicians Committee for Responsible Medicine has filed a complaint with the National Institutes of Health and USDA, requesting an investigation into decades-long alcohol-related experiments on nonhuman primates at Oregon Health & Science University. The ongoing experiments have cost over $70 million and involve inducing binge-drin...
Researchers have determined the near-atomic-resolution structure of the human ATR–ATRIP complex, clarifying key features and interactions. The study identified novel binding modes for two clinical ATR inhibitors, VE-822 and RP-3500, providing insights into designing next-generation therapies.
Researchers discovered novel small-molecule inhibitors targeting the WDR5-MYC protein-protein interaction, demonstrating improved inhibitory activity compared to reference compounds. The lead compound, 9c-1, showed a 35-fold enhancement in activity and sub-micromolar binding affinity.
Researchers at Ruhr-University Bochum successfully produced human DNase1 in yeast cells for the first time, overcoming previous challenges. The achievement could lead to a more affordable and efficient method for manufacturing this enzyme, which is currently used to treat cystic fibrosis.
West Virginia University researchers have created a model to redesign introductory college mathematics courses, aiming to increase mathematical literacy among graduates. The SUMMIT-P model encourages interdisciplinary partnerships and applies mathematical concepts to real-world problems across various disciplines.
A recent study published in The Journal of Prevention of Alzheimer's Disease found that evening people experience a greater rate of cognitive decline over time. This decline is attributed to unhealthy behaviors such as smoking and poor sleep habits, which can be mitigated by working with one's natural chronotype.
The Association for Computing Machinery has recognized five individuals with awards for their impactful service to the computing field. Manish Parashar received the ACM Distinguished Service Award for his leadership in furthering the transformative impact of computer science on science and engineering.
A University of Florida Health study found that earlier and more consistent daily activity patterns are associated with better heart and lung fitness in older adults. The research suggests that understanding individual circadian rhythms could lead to personalized health strategies, including tailoring activity and treatment schedules.
Scientists at the University of Innsbruck have successfully observed emergent anyonic behavior in a one-dimensional ultracold bosonic gas. This breakthrough enables the creation of exotic quasiparticles with distinct statistical properties, which could potentially overcome limitations of current quantum processors.
A study published in PLOS One found that domestic cats can discriminate between familiar and unfamiliar humans based on their odor. Cats spend longer sniffing the odor of a stranger than that of their owner, suggesting they can identify human scent patterns.
A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
A new algorithm standardizes care for children with sickle cell disease who present to the ED with a fever, reducing hospitalizations by 10% without increasing readmissions. The algorithm uses predefined risk factors to determine treatment, making it safer and more efficient.
A study of firms in China found that trade shocks have a positive impact on managerial behavior, improving investment decisions and reducing inefficiencies. The researchers discovered that tariffs and sanctions concentrate managers' minds on efficiency and focus resources towards more lucrative projects.
A new study from Michigan State University found that planting too much genetically modified corn designed to fight off the corn rootworm can cause more harm than good. The study estimates that reducing the Bt planting rate could save farmers $99 million in one-year benefits and $1.98 billion in lifetime benefits.
A Stanford University-led study found that modest patches of tree cover can reduce the presence of invasive mosquito species known to transmit diseases like dengue fever. This strategy has the upside of keeping out a disease-carrying invasive species and can inform land use decisions in rural areas.
A cross-sectional study found a strong association between chronic cannabis use and endothelial dysfunction. The findings suggest that THC may contribute to the development of cardiovascular disease through distinct mechanisms, similar to tobacco smoking.
Researchers developed a high-throughput screening method using density functional theory and machine learning to identify optimal single-atom catalysts (SACs) for eNRR. The approach significantly accelerated the discovery process, outperforming traditional trial-and-error methods.
Researchers analyzed two years of data on electric buses in Ithaca, finding batteries consume 48% more energy in cold temperatures. Short-term strategies include storing buses indoors and limiting door opening time to improve performance.
Researchers from Zhengzhou University present a roadmap to stabilize lithium metal anodes by tailoring electrolyte formulations and coating the anode surface. The study identifies six core strategies, including artificial SEI layers, separator regulation, and solid-state electrolytes, to enhance battery performance and safety.
Researchers developed a capacitive micromachined ultrasonic transducer (CMUT) device that can operate in a constant-charge mode without external bias. The system delivers stable power for over two years, setting new records for ultrasonic wireless power in biomedical applications.
Scientists have designed human-made molecules that self-assemble into stacked rings, allowing charge and energy to circulate freely, echoing photosynthesis. This breakthrough could lead to improved energy generation and advanced electronics.
Four researchers — Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain — are awarded the Merkin Prize for developing CAR T-cell therapy, a groundbreaking form of personalized cancer immunotherapy. The technology has led to durable remissions in tens of thousands of patients with previously incurable blood cancers.
A new study reveals that women experience greater severity of anger, irritability, and feeling out of control during premenses rather than postmenses. Additionally, symptoms tend to worsen as women approach the menopause transition, regardless of reproductive age.
Researchers found GPT-4o exhibits humanlike cognitive dissonance by changing its views on Vladimir Putin after being given the illusion of choosing essay topics. The AI's responses mirror human psychology's tendency to rationalize past behaviors, highlighting the fragility of its opinions.
A new study found that increasing infant-directed singing can improve infant mood and have a positive impact on caregivers' health. Researchers explored the effects of a simple music enrichment program, which encouraged parents to sing more frequently to their babies, on infant mood, stress, sleep quality, and music use.
AGA President Dr. Lawrence Kim is an endoscopy expert and diversity champion who will ensure the society is inclusive for all gastroenterologists. He aims to secure research viability and support next-generation leaders.
Researchers at the University of Maryland Baltimore County have made an important discovery about how cells move through tissues, combining mathematical modeling with advanced imaging to show that physical shape and chemical signals interact. The study's findings could inform new strategies for controlling cell movement via medical tre...
Texas A&M University researchers have developed a customizable vessel-chip method that can mimic various blood vessel structures, enabling more accurate models of vascular disease. The chip technology enables patient-specific research and pharmaceutical testing, with the potential to cure vascular diseases.
A new Yale study found that few bird species can escape the effects of climate change due to their limited migration capabilities. Despite some species being able to move northward or to higher elevations, they still experience significant temperature increases.
A team of scientists from SR-Tiget has identified a unique window shortly after birth to deliver lentiviral vectors directly into the bloodstream, enabling gene transfer and long-term engraftment. This approach shows promise for treating some genetic blood disorders without stem cell transplantation or chemotherapy.
Research reveals that Alaska wolves consuming sea otters have unprecedented mercury levels, potentially driven by climate change and coastal ecosystem changes. The study, led by University of Calgary ecotoxicology expert Ben Barst, found higher mercury concentrations in wolves from Pleasant Island compared to mainland Alaskan wolves.
Researchers propose therapeutic robots exhibit autonomy, responding only when users are calm and emotionally regulated, to foster trust, empathy, and fine-tuning. This approach has the potential to transform robotic therapy and human-robot interaction in fields like social skills development and emotional coaching.
A study published in Ecology and Evolution found that the digestion process of birds of prey, such as owls and hawks, can significantly impact the ratios of isotopes in their pellets and droppings. This means that previous studies relying on these samples may have inaccurate results when trying to determine an animal's diet or environm...
Aerial robots are limited to manipulating rigid objects, but Lehigh University researcher David Saldaña aims to expand their capabilities with an adaptive controller and reinforcement learning. His research has potential applications in construction, disaster response, and industrial automation.
Researchers found that unconditional cash transfers improve breastfeeding rates and have little impact on postpartum mood. UCTs ease financial strain, allowing parents to rest and bond with their baby, leading to better child development and stronger families.
Researchers examined baseline characteristics of adolescent and young adult (AYA) cancer survivors seen in oncology primary care clinic, finding high rates of comorbidities and cardiovascular disease. They also studied the overexpression of IRAK4 protein in acute myeloid leukemia (AML) cells, with potential implications for treatment.
Researchers from USTC have developed a novel method to degrade PTFE and PFASs at low temperatures using supercapacitor-assisted electrophotocatalysis. The process achieves high efficiency with minimal energy consumption, providing new perspectives for solving environmental problems.
A study found that rising temperatures in the Middle East and North Africa are associated with higher rates of these cancers. The prevalence of the different cancers rose by 173 to 280 cases per 100,000 people for every additional degree Celsius.
The new guidelines aim to improve health outcomes by providing evidence-based recommendations for managing VTE in children. Direct oral anticoagulants are now recommended as a first-line treatment option in many cases.
A recent study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows that less bitter-tasting pea protein hydrolysates can form bioactive peptides during digestion, which induce satiety signals via bitter taste receptors. The study reveals molecular mechanisms that can be used to optimize the tas...
A new study investigated people's moral judgments on euthanasia decisions made by AI and robots compared to human doctors. The research found that people generally prefer decisions made by humans over AI in end-of-life care situations.
Researchers found that accumulated mitochondrial DNA mutations do not impair respiratory function in mice, contradicting the 'mitochondrial theory of aging'. This study suggests a reevaluation of the relationship between mtDNA mutations and premature aging symptoms.
A study by researchers at the University of Arizona Health Sciences found that vaccinated people generated an overall protective immune response to Delta and Omicron strains, with slightly fewer antibodies for the mutated parts of the virus. The research suggests that immune changes due to antigenic imprinting may not be a significant ...
Politecnico di Milano will contribute to the RAMSES mission, studying Apophis' physical and dynamic properties through imagery and data gathered during its flyby. The university's team developed autonomous navigation algorithms that will serve as a test platform for new technologies.
Researchers used cryo-electron microscopy to visualize the 3D structure of sulfite reductase, a protein enzyme that breaks down sulfur into hydrogen sulfide. This breakthrough allows scientists to better understand how the enzyme functions and its potential applications in industries such as drug manufacturing.
The study systematically examines humins formation mechanisms from cellulose and hemicellulose feedstocks, highlighting the role of lignin in pseudo-lignin formation. It provides insights into factors influencing humins generation and proposes strategies for inhibition and value-added applications.
Christopher Flowers is being recognized for his commitment to mentoring young oncology professionals. He has advanced the development of multiple new treatments and helped characterize disparities in outcomes among patients with lymphoma.