The study, published in Nature Aging, found that sildenafil reduces the likelihood of developing Alzheimer's disease by 69% compared to non-users. Sildenafil also shows promise in treating the disease by increasing brain cell growth and decreasing hyperphosphorylation of tau proteins.
A new model identifies a symptom of dangerously high levels of polarization: a group's inability to unite in the face of external threats. Researchers found that extreme polarization can lead to a tipping point, where even a shock fails to reverse the self-reinforcing dynamics of division.
A study found that long-term cannabis smokers have increased levels of Actinomyces meyeri in their saliva, which correlates with the length of cannabis use. This bacterium was shown to decrease activity and increase beta-amyloid production in mice, suggesting a link between oral microbiome disruption and brain health.
Researchers at Illinois provided insight into the signal transduction mechanism utilized by Staphylococcus aureus's TCS ArlRS in response to host-imposed manganese and glucose starvation. The study found that histidine kinase ArlS is necessary for activation of response regulator ArlR under both manganese and glucose-limited conditions.
A study by VUB researcher Ari Ximenes uncovered factors that prevent mangroves from spreading in South America. Longshore drift and chilling temperatures are major factors hindering the southward expansion of mangrove species.
Polarization in politics and social networks is a complex system that undermines cooperation and diversity, threatening democracy's resilience. The studies examine how polarization arises from individual actions and interactions, leading to a loss of diverse perspectives and solutions.
A new study from the University of South Australia found that vitamin D deficiency is associated with a higher risk of heart disease and higher blood pressure. Increasing vitamin D levels in deficient individuals may prevent up to 4.4% of all CVD cases, according to the research.
Researchers developed a novel lithium-containing crosslinked polymeric material, LiGL, which exhibits exceptional protection effects on lithium metal anodes. The material achieves superior cycling stability, even after over 20,000 Li-stripping/plating cycles without failures.
Fatima Bagheri, a doctoral student in physics at the University of Texas at Arlington, has received a $200,000 National Science Foundation Postdoctoral Fellowship. She plans to investigate exoplanets' magnetic fields and their potential ability to support life, building on her previous research on geomagnetic storms.
Researchers at UC Berkeley have developed a new CRISPR editing technology that enables simultaneous editing of genes in multiple cell types and species within a microbial community. This approach, called community editing, has the potential to track edited microbes and understand their functions within complex ecosystems.
Researchers found that subjects who underwent cataract surgery had a nearly 30% lower risk of developing dementia compared to those who did not. The results persisted for at least a decade after surgery and were associated with lower risk of Alzheimer disease dementia specifically.
A $3.1 million NIH grant will fund a trial testing multidisciplinary telehealth intervention to reduce racial disparities in blood pressure control and stroke recurrence among adult stroke survivors. The study aims to identify social determinants of health that impact outcomes and explore ways to address them.
An analysis of Germany, Sweden, and the UK's handling of the COVID-19 crisis found that a lack of transparency around policy decisions, mixed messaging, and increased questioning of government legitimacy fueled public distrust. The study suggests that crisis preparedness and resilience framing should encompass governance structures tha...
Researchers found that most cases of suspected COVID-19 vaccine-related myocarditis in people younger than 21 are mild and resolve quickly. The study suggests that the benefits of COVID-19 vaccination far exceed the rare risks of adverse events, including myocarditis.
Researchers found that iron played a crucial role in the development of complex life forms on Earth due to its essential nutrient properties. The study suggests that the amount of iron in a planet's mantle may indicate its potential for supporting life.
A study by Boston Children's Hospital found that COVID-19 vaccination-related myocarditis is usually mild and has a fast clinical recovery rate in adolescents and young adults. However, long-term monitoring of heart health is recommended due to potential cardiac complications.
A study by University of Copenhagen researchers reveals that thousands of tigers are bred on farms and used to produce illegal traditional medicines. Buyers in Vietnam prefer wild tigers' bones over farmed ones due to perceived potency, while also seeking high tiger bone content.
Researchers have found no dark matter in the ultra-diffuse dwarf galaxy AGC 114905, which can be explained by normal matter. The discovery confirms previous measurements and raises questions about the existence of dark matter in galaxies.
A recent study published in Methods in Ecology and Evolution found that local environmental knowledge is a valuable tool for conservation in the Amazon, comparable to other scientific methods. Local ecological knowledge proved to be more accurate than 10 years of conventional scientific monitoring for animal abundance in the Amazon.
A recent study published in Toxicological Sciences suggests that exposure to wildfire smoke can lead to premature aging, dementia, depression, and psychosis. Researchers found that tiny particles from woodsmoke can travel thousands of miles and reach the brain, causing age-related changes in brain tissue.
A recent study found that US adults experienced higher blood pressure levels during the COVID-19 pandemic due to increased sedentary behavior, poor eating habits, and stress. The American Heart Association emphasizes the need for regular exercise, a healthy diet, and monitoring blood pressure to manage cardiovascular risk factors.
The new nine-part focus seminar series aims to address racial and ethnic disparities in healthcare through proven strategies such as team-based care and positive partnerships. The researchers emphasize the importance of social determinants of health and social justice approaches to improve health equity in cardiology.
Research reveals that tree root systems are a significant source of methane emissions in wetland areas, including the Amazon basin. The study suggests that existing models may be underestimating methane emissions by neglecting the role of trees.
A new opinion piece argues that hospitals have an ethical duty to care for unvaccinated severe COVID-19 patients, even if it means delaying non-emergency procedures for vaccinated individuals. The author suggests a contingency care standard prioritizing emergency life-support regardless of vaccination status.
A study of HIV-positive black and Latino men found that methamphetamine use combined with intimate partner violence boosts inflammatory and antiviral genes, leading to immune system exhaustion. This combination may increase the risk of developing cardiovascular disease and other disorders.
Between 2015 and 2019, Medicare spending on drugs with an accelerated approval indication more than doubled, reaching $9.1 billion in 2019, primarily driven by Part B drugs. The study's findings highlight the growing concern of rapidly increasing costs associated with these medications.
A new study by the University of Pittsburgh School of Medicine highlights the link between stress and alcohol craving among Black individuals. The research found that higher stress levels are associated with stronger alcohol cravings for Black participants, but not white participants, suggesting a process of drinking to cope with stress.
A new particulate saponin/TLR agonist vaccine adjuvant has been shown to alter lymph flow and modulate adaptive immunity. This study demonstrates the potential of this ingredient as a more effective vaccine booster.
Researchers investigate glacial ice melting that releases acoustically distinct pressurized underwater bubbles, providing a potential tool for monitoring climate change's impact on glaciers. The team's experiments will permit the long-term monitoring of ice loss and its link to water temperature.
A recent review reveals alarming increase in physician burnout among diagnostic radiologists, with causes including lack of control, social isolation and technological demands. Possible solutions include heightened engagement, dedicated reading room assistants and mindfulness techniques.
A study by University of Seville researchers reveals that messenger RNA modifying factors play a crucial role in the repair of DNA breaks. The discovery could lead to better understanding of rare diseases and cancer. Messenger RNA editing facilitates the removal of trapped RNA molecules, allowing for proper DNA repair.
A new study from the University of the Basque Country found that social interaction and contact with family members have a significant positive impact on homeless people's perception of their health. Conversely, longer periods of homelessness and reduced social connections are associated with poorer health perceptions.
A study by the CDC found a strong association between obesity and diabetes, both of which are widespread in the U.S., and severe COVID-19 disease. In South Carolina, chronic diseases disproportionately affect Black communities, increasing their risk of developing severe COVID-19.
Researchers found that fish exposed to BPA exhibited feminizing effects on gonads, brain genes, and hormone levels, leading to changes in aggression and sex determination. In contrast, EE2 had less pronounced effects, with decreased aggression despite feminization of gonads.
A new study by UCL researchers found that people's motivation to seek information falls into three categories: expected utility, emotional impact, and frequency of thought. Those who prioritize these factors tend to seek information more, with better mental health reported by those seeking info on frequently thought-about topics.
Researchers at Skoltech have created an optoacoustic endoscopic probe that can analyze atherosclerotic plaques by forcing molecules to sound their presence. The device uses laser light to make biomarkers oscillate, producing ultrasound signals that can be detected by a sensitive microphone.
A new optical instrument will provide clearer images of the rhizosphere, enabling scientists to study chemical and biomolecular interactions between plants and soil. This research aims to mitigate the effects of climate change and develop more sustainable fuels and fertilizers.
A blind taste test by University of Copenhagen researchers shows Danes prefer conventional and organic farmed smoked salmon over wild-caught. The study reveals that people's expectations about a product affect their overall taste experience.
A study estimates that 55% of organic matter removed during wastewater treatment is refractory, leading to high greenhouse gas emissions. The researchers propose a new perspective on carbon neutrality in the industry by leaving non-toxic recalcitrant organic matter in the wastewater.
Scientists at La Jolla Institute for Immunology and MIT have discovered a new adjuvant called SMNP, which combines saponin and TLR agonist to boost the protective power of vaccines. The study found that SMNP triggers a strong immune response in mice, promoting lymphatic drainage and activating multiple parts of the immune system.
The 2022 Pharmacy Forecast Report notes that COVID-19 disruptions have led to increased roles for pharmacists in patient care, emergency preparedness, and technology. The report also emphasizes the need for equitable access to digital tools and explores strategies to mitigate supply chain issues.
A study at Karolinska Institutet found that individuals with a resting heart rate of 80 beats per minute or higher had a 55% higher risk of dementia. The association remained significant after adjusting for other cardiovascular diseases, suggesting a potential link between elevated heart rate and cognitive decline.
Researchers realized ultra-high precision search for exotic spin- and velocity-dependent interactions beyond the standard model, amplifying magnetic field signals. They used a quantum spin-based amplifier to study new physics theories, proposing a new class of bosons-nucleus coupling constraint.
A new study published in the journal Anatomical Record reveals that gharial species, native to India, suffer from nasal septal deviation, a condition common among humans. The researchers found that this deviated septum affects the breathing rate and may lead to high shearing stresses along the nasal walls.
Researchers have successfully determined the structure of the Lassa viral polymerase, a key component in viral replication, using cryo-electron microscopy. This breakthrough provides crucial insights into how to design drugs that can stop the infection, offering hope for developing an effective antiviral.
Research from Iowa State University found that using a supportive voice in the workplace signals approachability and trustworthiness, fostering strong interpersonal relationships and effective teamwork. This 'supportive voice' is more critical for team formation than previously thought, and can help employees move into leadership roles.
A study by Universitat Autonoma de Barcelona found that spending revenues on climate projects increases social acceptability of carbon taxes. The research also revealed that providing information on carbon taxes can increase acceptability, while the perception of fairness is a stronger factor in acceptability than effectiveness.
A meta-analysis of 17 controlled studies found Wraparound Care Coordination significantly reduces out-of-home placements, improves mental health functioning and school outcomes, and lowers overall care costs. The study also shows more positive effects for youth of color.
Researchers used creative methods to explore perceptions of air pollution with local communities in Nairobi's informal settlements. They found contrasting definitions of air pollution and differing views on who was responsible for solutions.
Researchers at Hokkaido University analyzed hundreds of women with ovarian granulosa cell tumors to improve understanding of the disease progression and response to therapy. They found that early-stage tumors rarely spread beyond the ovaries, and fertility-sparing surgery may be considered for younger patients.
Researchers at Tohoku University have discovered a novel two-step nucleation process in the development of 2D monolayer transition metal dichalcogenide (TMD). This breakthrough allows for improved quality control and higher growth rates, enabling the synthesis of ultra-high quality TMD.
A team of researchers used CARS microscopy to analyze the fat arrangement in foie gras and duck pâté. They found that foie gras had a harder, more brittle texture due to its irregularly shaped fat network. The study provides new insights into the relationship between microstructure and food texture.
Researchers have designed a new nanoparticle adjuvant that significantly improves antibody production following vaccination against HIV, diphtheria, and influenza. The adjuvant speeds up lymph flow to lymph nodes, helps antigens reach B cells before breaking down, and activates inflammatory cytokines for a stronger response.
A new PI-based nanocomposite film with enhanced mechanical properties and atomic oxygen resistance has been developed. The double-layer nacre-inspired structure improves the material's performance in LEO applications, making it a promising aerospace protective material.
Researchers at UC San Diego School of Medicine developed a shortened 7-item version of the SD-WISE-28 to assess wisdom. The Jeste-Thomas Wisdom Index has high validity and positive correlations with resilience, happiness, and mental well-being.
Researchers discovered that infections improve the production and function of naïve T cells, the body's first line of defense against disease. This mechanism involves interleukin 7 and MHC molecules, which signal naïve T cells to stay alive and receive optimal metabolic signals.
Researchers develop novel detection method to identify high-dimensional entanglement states, overcoming challenges faced by traditional methods. The study proposes a protocol to automatically search for optimal certification methods, enabling the creation of high-dimensional quantum information processing systems.
Researchers developed a green synthesis method for ammonia production using green tea as a reducing agent. The study found that the optimized sample showed 2.93-fold enhanced photocatalytic activity and increased NH3 selectivity, outperforming bulk g-C3N4 under simulated sunlight irradiation.
Femtosecond laser precision engineering enables micro/nano-structure creation with high resolution and dry processing. Key challenges include achieving small heat affected zones and ensuring sufficient processing speeds for industrial needs.
The nTIDE November 2021 Jobs Report reveals historic employment gains for people with disabilities, with the employment-to-population ratio increasing to 34.6% and labor force participation rate rising to 37.7%. These gains surpass pre-pandemic levels and historic highs.