A recent study has identified a new mechanism by which oral cancer cells acquire radioresistance through the transfer of microRNA, specifically miR-503-3p. This discovery brings hope for the development of new treatments for radiation-resistant oral cancer.
Researchers at Linköping University developed a mathematical model to describe global climate target achievement and predict unanimity in climate talks. The model shows how countries influence each other over time, highlighting the importance of inclusive plenary sessions and informed parties.
Researchers have discovered that vast ice forms on Pluto's surface are formed by the sublimation of nitrogen ice, powering convection in the ice layer of Sputnik Planitia. This process is consistent with climate models and has implications for other planetary bodies.
The university is coordinating the second funding period of the program, which aims to develop innovative, high-performance molecular materials for various applications. The program will tackle photophysical and photochemical challenges, as well as fundamental questions associated with these materials.
Researchers are exploring how an engineered adeno-associated virus (AAV) can compensate for missing protein or swap out genetic mutations that cause vision problems. AAV has been found to be beneficial and is being used as a tool to deliver genes that work as they should.
A recent analysis of children's books over the last 60 years reveals a persistent bias towards male protagonists, with slighter gaps in more recent decades. The study highlights concerns that such representation may contribute to biases in society, particularly for girls.
A study in mice suggests that transplanted brown fat can reduce type 2 diabetes risk factors after a heart attack by dampening gene activation linked to negative effects. The transplantation method could help researchers understand the mechanisms behind this protective effect and potentially lead to therapeutic applications.
A new study published in Menopause found that postmenopausal women aged 45-54 are more likely to develop overactive bladder syndrome. Stress urinary incontinence symptoms, however, increased with obesity and multiple births. The study suggests a significant association between age and menopause status with increased urinary symptoms.
University of North Carolina researchers have created a rapid sensing COVID-19 test strip using the natural biology of epithelial cells. The test is inspired by the virus' affinity for sugars in the glycocalyx matrix.
A digital version of cognitive behavioral therapy (dCBT) has been shown to reduce insomnia, depression, and anxiety during pregnancy. The treatment also reduced symptoms of insomnia and depression in non-depressed women for up to six months postpartum.
Research from Queen Mary University of London and Cardiff University found that certain MS treatments can reduce Covid-19 vaccine effectiveness in people with MS. The largest peer-reviewed study on the topic provides high-quality evidence to inform clinicians' guidance on treatment options.
Researchers from The Ohio State University developed a novel method to supplement cow milk with vegetable protein using readily available dairy processing equipment. This innovation combines the benefits of casein micelles with pea protein to create functional, multisourced dairy products that can help bolster declining fluid milk sale...
Younger children report need for social interaction, while older students seek support for anxiety and educational pressures. The study surveyed 6291 young people in Wales to understand factors influencing their wellbeing during the pandemic.
A recent study in Frontiers in Marine Science has found over 100 underwater animal species thriving on a 2,200-year-old Mediterranean shipwreck. The 'ecological memory' of the wreck provides valuable insights into how marine animals colonize empty sites and form diverse communities.
A lighter, more robust knee brace for the elderly has been developed through a collaboration between Delsson and Nanyang Technological University. The X-Brace uses lightweight plastic and assistive springs to reduce weight by 30%, making it easier for patients to walk with less pain.
A new study reveals that the Little Ice Age was triggered by an unusually warm episode in the late 1300s, with strong northward transfer of warm water and high solar activity contributing to the phenomenon. The researchers found that this warming event led to rapid arctic ice loss and subsequent cooling of North Atlantic waters.
A recent University of Cincinnati study investigated how mindfulness affects mind wandering and found that while it can be effective in reducing mind-wandering thoughts, the results differ depending on the research methodology. The study suggests using computer-based testing methods to measure mind wandering for more reliable findings.
A Trinity College study found that severe COVID-19 patients who received care outside of an ICU had a higher mortality rate compared to those in the ICU. The study highlights Ireland's shortage of ICU beds and emphasizes the need for increased critical care capacity.
Researchers analyzed 47,727 lead measurements from 1,094 schools in Massachusetts to identify schools with high lead levels. They found that 12% of fixtures had lead levels above 15 parts per billion, with most problematic fixtures concentrated in just 34% of schools.
SARS-CoV-2 enters human cells via spike proteins interacting with ACE2 on cell surfaces. Advanced microscopy revealed the dynamic nature of these interactions, enabling potential strategies to block viral entry.
A study of 19,000 NFL players found a significantly higher incidence of ALS diagnosis and death among players compared to the U.S. male population.
A University of California, Riverside study found that diet impacts taste sensitivity and food choice in fruit flies, using macronutrients like sugars and amino acids for survival. Flies adjusted their taste preferences based on dietary imbalances, influencing food choices to regain a balanced diet.
An international study found that masks can evoke fears of Covid-19 in anxious individuals, leading to avoidance behavior. Younger people are more cautious than older counterparts, suggesting media consumption plays a role. Policymakers should focus on reducing mask-related dread to promote public acceptance.
A new study using the world's largest twin registry data finds that hormone levels before birth may contribute to migraine risk in adulthood. The research also suggests that genetic factors for migraine risk are different between men and women, potentially leading to more effective treatment options.
A recent study from Tel Aviv University found that mothers' smartphone use reduces toddler interaction by a factor of four. Reduced interaction can have far-reaching consequences on child development, including language and social skills. The study also found no significant difference between browsing smartphones and reading magazines.
Scientists have made a breakthrough in controlling the formation of vacancies in silicon carbide, a semiconductor material. The team's simulations tracked the pairing of individual vacancies into a divacancy and discovered the optimal temperatures for creating stable divacancies. This discovery could lead to highly sensitive sensors an...
Researchers at Duke University developed a lightweight material that traps thermal energy when dry but opens tiny vents to let heat escape when a person starts sweating. The material has potential as a patch on clothing to help keep the wearer comfortable, expanding thermal comfort zones by 30%.
A University of Cambridge-led study found that rising housing prices can significantly increase 'openness' among US residents within a few years. This trait captures levels of curiosity and creativity.
A new study found that Brood X cicada emergence holes significantly increased water infiltration rates in undisturbed areas but not in disturbed sites. The holes filled with sediment and debris over time, causing a rapid decrease in infiltration at disturbed locations.
A phase 1/2 clinical trial tested an L-NMMA and taxane combination in patients with chemoresistant TNBC, showing a remodeling of the immune environment in responders. The study's results warrant further investigation in larger trials to identify potential biomarkers for predicting response.
Researchers at PSI have developed a platform to measure biased signalling in G protein-coupled receptors (GPCRs), enabling selective therapeutic effects and fewer side effects. By testing specially designed bivalent ligands, they can bias signalling towards desired pathways.
Researchers found that global databases revealed a net loss of regional floristic uniqueness due to the spread of alien plants. The study highlighted biogeographic factors like climate distance and anthropogenic factors such as shared administrative history contributing to homogenization of regional floras.
A team of researchers from Harvard University has observed exotic fractional states at low magnetic field in twisted bilayer graphene for the first time. The discovery could lead to robust quantum bits and new types of quantum computing applications.
A study by the URV and IISPV found that people exposed to high levels of PM10 in cities suffer from more severe COVID-19 cases. Chronic exposure to PM10 was estimated to increase the risk of severe COVID-19 by 3% for every 1µg/m³ increase.
Researchers at KAUST have developed a nanocomposite that absorbs X-rays with near-perfect efficiency and re-emits the energy as light. This innovation improves high-resolution medical imaging and security screening, with detection limits up to 142 times lower than traditional methods.
An analysis of data from 16 US states reveals a major increase in wine and spirit sales during the COVID-19 pandemic, accompanied by changes in the relationship between alcohol sales and business visits. Sales of spirits and wine increased by as much as 20-40% in some states, while beer sales declined overall.
A novel vaccine, TOH-Vac1, replicates inside the body's cells and generates a powerful immune response in mice and monkeys. The vaccine is based on a strain of vaccinia virus used to vaccinate against smallpox and can be programmed to protect against multiple variants.
Researchers found that successful mental health programs built on social connectedness, accountability, trust, and resilience can effectively address the needs of individuals with chronic health conditions. These elements are interconnected and crucial for developing effective interventions.
A recent study found that high temperatures inhibit the accumulation of flavonoids in plants, leading to reduced plant fitness and altered flower color formation. The researchers identified a novel transcription factor CmMYB012 as responsible for suppressing flavone biosynthesis and anthocyanin content.
The University of Texas at El Paso has received a $917,000 grant from the Air Force Office of Scientific Research to develop advanced materials for national defense, power electronics, and security. UTEP students will perform cutting-edge research on gallium oxide-based semiconductors.
Researchers at Yokohama National University have developed an interface approach to control diamond nitrogen-vacancy centers, allowing direct translation to quantum devices. This enables remote quantum entanglement and secure information exchange over long distances.
A recent study published in Canine Medicine and Genetics found that French Bulldogs have a significantly higher risk of being diagnosed with 20 common health disorders compared to other breeds. The authors propose breeding towards more moderate characteristics to reduce these risks.
A study examined COVID-19 mRNA vaccine effectiveness in older male veterans before and during the Delta variant emergence, finding reduced protection. The study aimed to assess vaccine effectiveness in this specific population, which is critical for informing public health strategies.
A new study found that krypton isotopes in the deep mantle reveal a clearer picture of Earth's formation, contradicting the popular theory of volatile elements arrival. The research suggests that planetesimals from the cold outer solar system bombarded the Earth early on.
A new method of predicting battery failure has been developed, showing accuracy 15-20% higher than current approaches. The technique uses advanced probabilistic machine learning and is applicable to any battery with a simple electrical circuit model.
A novel 'virtual segmentation' method enables accurate visualization of microtomography imaging of Egyptian mummies. This technique helps researchers reconstruct detailed anatomical structures of ancient animals, shedding new light on their biology and evolution.
A novel approach may reduce the serious adverse effect of cytokine release syndrome associated with chimeric antigen receptor (CAR) T-cell therapy. Supressing interferon gamma (IFNγ) appears to prevent activation of macrophages and other immune cells that drive the syndrome without impacting CAR T-cell efficacy.
A team of political scientists argues that a self-enforcing democracy requires parties to refrain from exploiting electoral rules, citing fear of retaliation and partisan sorting. The study highlights the threat of gerrymandering and voter suppression to democratic representation.
The worldwide incidence and mortality rates for stroke decreased slightly over the three decades, but the overall numbers are still high. Ischemic stroke is highly preventable, and more resources should be devoted to prevention, especially in low- and middle-income countries.
A study led by Alice Cravotta examined the impact of restricting hand gestures on speech. The researchers found that gesturing did not affect the fluency or acoustic characteristics of speech, but participants produced speech with different prosodic features when gesture production was prevented.
A study published in Frontiers in Psychology found that older adults are less susceptible to Covid-19 scams due to their higher receptivity to 'bullshit', which prevents them from perceiving false statements as valid. This contradicts the common perception that older adults are more likely to fall victim to fraud.
Phytoplankton are critical to life in ocean waters, and their seasonal availability is shifting due to climate change. Researchers found that carbon produced by phytoplankton is sinking into the deep ocean, impacting global nutrient availability and ocean ecosystems.
Researchers from KAIST have developed a new technology to stabilize the electrode-electrolyte interface of lithium metal batteries, leading to improved performance and lifespan. The technology uses fluorine- and nitrogen-donating ionic additives to create a dual-layer solid electrolyte interphase.
Researchers developed a new fabrication method for wearable pressure sensors that enhance durability, sensitivity and transparency. The sensors can detect various body movements and health indicators, such as pulse, sweat, and temperature.
A team built a virtual reality system to study the search behavior of male silkmoths, revealing that accurate information from multiple modalities increases success rate. The system also showed a modulation of behavior based on environmental complexity.
Researchers demonstrate that quantum networks' predictions differ when postulates are phrased in real numbers. The study proposes an experimental setup involving two sources and three measurement nodes, where complex quantum theory's predictions cannot be expressed by their real counterparts.
A recent NIH study found that pregnant women with disabilities have a significantly higher risk of severe pregnancy- and birth-related complications and death. Women with physical, sensory, or intellectual disabilities are more likely to experience preterm birth, hypertensive disorders, gestational diabetes, and cesarean delivery.
A prospective study found that ultrasound alone adequately completed the diagnostic evaluation of 71.2% of noncalcified lesions, diagnosed 92.1% of cancers, and yielded a sensitivity of 94.9%. Radiologists should consider performing ultrasound first for digital breast tomosynthesis-recalled noncalcified masses.
The Forest Condition Monitor tool uses color-coded visualization to identify areas of high-stress forests across Europe, allowing for targeted conservation efforts and research. Scientists can study these regions to understand eco-physiological processes and warn forest owners of potential risks.
Researchers at Stanford University have created a robotic hand with a gecko-inspired grip that can handle both delicate and heavy objects. The 'farmHand' gripper uses gecko-adhesive pads and has a unique finger design to enable both dexterity and strength.