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Science News for December 17, 2021


A more targeted therapy to treat inflammatory bowel disease

Researchers at UC Riverside have discovered that targeting the TNFR1 receptor may be a more effective approach to treating inflammatory bowel disease. By selectively blocking TNFR1, they found significant benefits in mice with Crohn's-like ileitis, suggesting this approach could offer a new opportunity for healing.

SourceUniversity of California - Riverside·JournalJournal of Crohn s and Colitis·TypeExperimental study·DateDec 17, 2021

Testosterone drives the dark side of meerkat success

In meerkat societies, testosterone-driven aggression enables cooperative breeding by creating a hierarchy where subordinates help raise the matriarch's pups. Researchers found that matriarchs' high testosterone levels drive their aggressive behavior, which maintains group structure.

SourceDuke University·JournalNature Communications·TypeObservational study·DateDec 17, 2021

Major US electric utility companies may reduce power sector emissions by one-third, if they stick with their climate pledges

A recent study found that major US electric utility companies' voluntary climate pledges could lower net emissions by roughly 560 million metric tons of CO2 equivalent, an amount equal to one-third of 2018 US power sector emissions. This reduction is on top of existing policies and could play a vital role in climate change mitigation.

SourceCell Press·JournalOne Earth·TypeData/statistical analysis·DateDec 17, 2021

Inequities in use of diabetes medications

A study of 1.1 million patients with type 2 diabetes found disparities in the use of GLP-1 receptor agonists by racial and ethnic groups, as well as by sex and socioeconomic status. The findings highlight concerns about unequal access to effective diabetes care.

SourceJAMA Network·JournalJAMA Health Forum·DateDec 17, 2021

Pioneering new technique to barcode cells

Scientists have developed a pioneering new technique to barcode individual cells more accurately and efficiently. The method combines artificial intelligence with microfluidics, allowing for real-time analysis of single cells and enabling the efficient sorting and counting of cells.

SourceUniversity of Exeter·JournalAdvanced Materials Technologies·DateDec 17, 2021

Well insured: Forests with many tree species grow more consistently

Research found that forests with diverse tree species exhibit higher growth stability and biomass production under fluctuating climate conditions. This is due to the diversity of species characteristics, such as asynchrony in growth patterns and drought-tolerance strategies, which counterbalance negative impacts of extreme weather events.

SourceGerman Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig·JournalScience Advances·TypeObservational study·DateDec 17, 2021

General anaesthesia impacts brain functioning less than other patient risk factors, data spanning 12 years suggests

A Dutch study of over 1,800 adults found that repeated general anaesthetics have little impact on long-term cognitive decline compared to patient factors such as high blood pressure, type 2 diabetes, smoking, and educational level. Cognitive decline was more strongly linked to these factors than to the number of surgeries under general...

SourceThe European Society of Anaesthesiology and Intensive Care (ESAIC)·JournalEuropean Journal of Anaesthesiology·DateDec 17, 2021

h-BN/NiS2/NiS nanocatalysts for removing rhodamine B and Cr(VI) in wastewater

The h-BN/NiS2/NiS nanocatalyst exhibits high photocatalytic performance for removing Cr(VI) and rhodamine B from wastewater, with a synergistic effect enhancing its activity and stability. The composite material displays uniform dispersion of NiS2/NiS nanocrystals, increased specific surface area, and enhanced light absorption.

SourceHigher Education Press·JournalFrontiers of Chemical Science and Engineering·TypeExperimental study·DateDec 17, 2021

Unfolding the blindness proteins through fly eyes

Scientists have identified a crucial mechanism for Rhodopsin production in fruit flies, which may lead to a better understanding of retinitis pigmentosa and vision loss. The study reveals that the EMC protein complex is essential for the proper folding and insertion of Xport-A, a key chaperone of Rhodopsin.

Perovskite solar cell with ultra-long stability

Researchers from Forschungszentrum Jülich have developed a perovskite solar cell with exceptional stability, retaining 99% of its initial efficiency after 1450 hours of operation. The new design features a double-layer polymer structure that protects the contact point and ensures stable conductivity.

SourceForschungszentrum Juelich·JournalNature Energy·TypeExperimental study·DateDec 17, 2021

New autism marker discovered in kids

Scientists have discovered a brain protein, CNTNAP2, that quiets overactive brain cells and is at abnormally low levels in children with autism. The protein can be detected in cerebrospinal fluid, making it a potential biomarker for diagnosing autism and treating epilepsy.

SourceNorthwestern University·JournalNeuron·TypeExperimental study·DateDec 17, 2021

Rollercoaster of emotions: Exploring emotions with virtual reality

A recent study at the Max Planck Institute for Human Cognitive and Brain Sciences used virtual reality to simulate emotionally engaging situations, allowing researchers to measure brain activity and find a correlation between alpha oscillations and emotional arousal. This discovery has implications for psychological therapy and treatment.

SourceMax Planck Institute for Human Cognitive and Brain Sciences·JournaleLife·TypeExperimental study·DateDec 17, 2021

Understanding cobalt’s human cost

Researchers studying cobalt mining in the DRC found associations with violence, substance abuse, and health challenges. The study highlights the need for social life cycle assessments to understand emerging technologies' impact on human well-being.

SourceNorthwestern University·JournalOne Earth·TypeCase study·DateDec 17, 2021

Loneliness among emerging adults increased slightly

A recent study found that loneliness among emerging adults (18-29 years old) has increased by about 0.56 standard deviations on the UCLA Loneliness Scale over a 43-year period. This slight increase is considered a warning signal for the need to design prevention and intervention measures against loneliness.

SourceRuhr-University Bochum·JournalPsychological Bulletin·TypeMeta-analysis·DateDec 17, 2021

Controlling the metabolism of cancer cells

Researchers at Leipzig University have discovered that cancer cells need the succinate receptor to control their metabolic rate. The receptor is found on the surface of various types of tumors and plays a crucial role in the survival of cancer cells.

SourceUniversität Leipzig·JournalCancer Letters·TypeMeta-analysis·DateDec 17, 2021

Heart disease-protective diabetes drug not used equitably, study finds

A recent study found significant inequities in the use of GLP-1 receptor agonists (GLP-1 RA), a medication typically used for treating diabetes, among different racial and ethnic groups. The study, published in JAMA Health Forum, showed that Black patients were 19% less likely to have a GLP-1 RA prescription compared to white patients.

SourceUniversity of Pennsylvania School of Medicine·JournalJAMA Health Forum·DateDec 17, 2021

The inaugural WHO classification of childhood tumors will provide a unified, updated resource for the diagnosis of pediatric cancers

The inaugural WHO classification of childhood tumors presents a single, updated compendium of all tumor entities in childhood or adolescence, divided by organ sites. This classification incorporates traditional morphology, immunohistochemistry, and molecular characteristics to provide essential criteria for definition of tumor types.

SourceAmerican Association for Cancer Research·JournalCancer Discovery·DateDec 17, 2021

Critically ill COVID-19 patients with acute kidney injury more likely to die than those with pre-existing chronic kidney disease

A new study presented at Euroanaesthesia found that critically ill COVID-19 patients with acute kidney injury are more likely to die in the ICU than those with pre-existing chronic kidney disease. The study also showed that dialysis treatment has little impact on survival rates for these patients.

SourceThe European Society of Anaesthesiology and Intensive Care (ESAIC)·JournalEuropean Journal of Anaesthesiology·DateDec 17, 2021