About The Study: This study found artemisinin partial resistance in Ugandan children with complicated malaria associated with the Pfkelch13 A675V variation and also found suboptimal 28-day efficacy of parenteral artesunate followed by oral artemether/lumefantrine therapy.
Corresponding Author: To contact the corresponding author, Chandy C. John, MD, MS, email chjohn@iu.edu .
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(doi:10.1001/jama.2024.22343)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the American Society of Tropical Medicine and Hygiene Annual Meeting.
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