An accompanying commentary by Jerome Niquet and Claude Wasterlain, of Epilepsy Research Laboratory, place this work in context with the complexity of cell-death pathways and highlight specific areas of future analysis that are still required to understand the molecular mechanisms at play in neuronal damage.
TITLE: Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy
AUTHOR CONTACT:
David C. Henshall
Robert S. Dow Neurobiology Laboratories, Portland, Oregan, USA.
Phone: 503-413-5260
Fax: 503-413-5465
E-mail: dhenshall@downeurobiology.org
View the PDF of this article at: http://www.jci.org/cgi/content/full/113/7/1059
ACCOMPANYING COMMENTARY: Bim, Bad, and Bax: a deadly combination in epileptic seizures
AUTHOR CONTACT:
Jerome Niquet
Epilepsy Research Laboratory, West Los Angeles, California, USA.
Phone: 310-478-3711 ext. 41974
Fax: 310-268-4856
E-mail: jniquet@ucla.edu
Journal of Clinical Investigation