About The Study: This cohort study found an association of parental diseases of despair (defined as a suicide attempt, alcohol-related disease, or substance use disorder) with youth suicidal events; this finding may be underlying the increase in adolescent suicidal behavior observed in the U.S. over the past 2 decades. Improved access to care for parents with diseases of despair and systematic screening and referral of their offspring could help to reduce the adolescent suicide rate.
Corresponding Author: To contact the corresponding author, David A. Brent, MD, email brentda@upmc.edu .
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(doi:10.1001/jamanetworkopen.2025.31442)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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