About The Study: This study found reduced incidence of cardiorespiratory hospitalization among those who received high-dose inactivated influenza vaccine vs standard-dose inactivated influenza vaccine, driven by a lower incidence of cardiovascular hospitalizations, and particularly heart failure hospitalizations. These differences should be interpreted as exploratory findings in the setting of a large randomized clinical trial with a neutral primary outcome.
Corresponding Author: To contact the corresponding author, Tor Biering-Sørensen, MD, MSc, MPH, PhD, email tor.biering@gmail.com .
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JAMA Cardiology
30-Aug-2025