What The Study Did: The results of this study including 650,000 children suggest that the incidence rate of SARS-CoV-2 infection with Omicron variant was six to eight times that of Delta variant in children younger than age 5, but severe clinical outcomes were less frequent than with Delta variant. Study limitations include potential biases introduced by the observational and retrospective analyses of electronic health records and the need for validation of the results from other data.
Authors: Rong Xu, Ph.D., of the Case Western Reserve University School of Medicine in Cleveland, is the corresponding author.
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(doi:10.1001/jamapediatrics.2022.0945)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Pediatrics