About The Study: In this cohort study, maternal plasma 25-hydroxyvitamin D levels throughout pregnancy were inversely associated with odds of offspring early childhood caries. These findings support the potential benefit of vitamin D supplementation before or during pregnancy in reducing the risk and severity of childhood dental caries.
Corresponding author: To contact the corresponding author, Yunxian Yu, M.D., Ph.D., email yunxianyu@zju.edu.cn .
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(doi: 10.1001/jamanetworkopen.2025.46166)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Network Open
Vitamin D Levels During Pregnancy and Dental Caries in Offspring
2-Dec-2025