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Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing

04.15.25 | PLOS

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Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing
Schematic overview of predicting preterm birth using promoter profiling of plasma cfDNA. Credit: Guo Z, et al., 2025, PLOS Medicine, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)

In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine : https://plos.io/3RuCJ9v

Article title: Genome-wide nucleosome footprints of plasma cfDNA predict preterm birth: A case-control study

Author countries : China, United Kingdom

Funding: This work was supported by project grants from the National Natural Science Foundation of China [81600404 to JT, 82270600 to JT, 81871177 to FY, 82271711 to XY, 82173001 to ZG]; Guangdong Basic and Applied Basic Research Foundation [2022A1515220204 to JT; 2024A1515012792 to ZG]; Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation [201905010003 to JT]; The Research Foundation of Guangdong Provincial Reproductive Science Institute [QD202201 to JT]. No funders had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

PLOS Medicine

10.1371/journal.pmed.1004571

Observational study

People

Competing interests: The authors have declared that no competing interests exist.

Keywords

Genetic Analysis Genetic Testing Pregnancy

Article Information

Journal
PLOS Medicine
DOI
10.1371/journal.pmed.1004571
Method of Research
Observational study
Subject of Research
People
COI Statement
Competing interests: The authors have declared that no competing interests exist.

Contact Information

Claire Turner
PLOS
medicinepress@plos.org

How to Cite This Article

APA:
PLOS. (2025, April 15). Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing. Brightsurf News. https://www.brightsurf.com/news/L3RZZ6Y8/preterm-birth-might-be-predicted-with-high-accuracy-with-new-cheap-non-invasive-test-based-on-cell-free-dna-collected-in-standard-early-pregnancy-testing.html
MLA:
"Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing." Brightsurf News, Apr. 15 2025, https://www.brightsurf.com/news/L3RZZ6Y8/preterm-birth-might-be-predicted-with-high-accuracy-with-new-cheap-non-invasive-test-based-on-cell-free-dna-collected-in-standard-early-pregnancy-testing.html.