Researchers report that administration of a nanosized liposomal formulation containing an analog of the signaling molecule cGMP helped reduce rod photoreceptor loss and restore retinal function in three different rodent models of hereditary retinal degeneration, a neurodegenerative condition that leads to loss of photoreceptors and blindness and that lacks effective treatments.
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Article #17-18792: "Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration," by Eleonora Vighi et al.
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Proceedings of the National Academy of Sciences