Articles tagged with Cgmp Signaling
Researchers found that intrinsically-photosensitive retinal ganglion cells (ipRGCs) use both microvillous and ciliary signaling mechanisms simultaneously. This discovery reveals a new pathway for transmitting light signals to the brain, which may have ancient origins on the evolutionary scale.
A new study reveals that cyclic AMP and cGMP bind to ion channels with distinct effects, shedding light on their roles in regulating cell functions. The findings could inspire new treatments for disorders involving ion channel malfunctions.
A new treatment approach uses a cGMP analogue in a drug delivery system to protect photoreceptors and restore retinal function in rodent models of the disease. The study shows promising results in reducing photoreceptor loss and restoring vision.
Researchers at the University of Bonn found that inflammation in abdominal fat blocks fat-burning by inhibiting cGMP signaling. Administering cGMP-stimulating active ingredients may be a possible starting point for treating obesity and preventing related complications.
A new study reveals that liver disease can impair learning ability by disrupting the glutamate-nitric oxide-cGMP pathway in the brain. Sildenafil treatment restored learning ability in rats with portacaval shunts and those with hyperammonemia, suggesting a potential therapeutic approach for patients with hepatic encephalopathy.