A study published by UC Davis Violence Prevention Research Program found that prior DUIs and other alcohol-related convictions among legal handgun owners in California significantly increased the risk of arrest for violent or firearm-related crimes. The increase was fourfold to fivefold, independent of other risk factors.
A recent study has provided the first details of how enteroviruses, which cause millions of infections worldwide annually, may enter the body through the intestine. The researchers used a mini-gut model to demonstrate that echovirus 11 induced significant damage to intestinal cells, facilitating passage into the bloodstream.
Enteroviruses cause millions of infections worldwide, with infant fatality rates approaching 20 percent. A new study uses a miniature gut model to reveal how these viruses enter the intestine, targeting specific cells and facilitating bloodstream entry.
The Temple Wedge Opioid (TWO) Treatment Program provides state-of-the-art care to pregnant women and their partners, addressing the growing issue of maternal opioid use. The Center of Excellence offers comprehensive treatment options, including medication-assisted treatment and psychiatric evaluation.
Researchers have discovered 30 genes as potential therapeutic targets for reversing Rett syndrome, a severe form of an autism spectrum disorder affecting approximately 15,000 girls and women globally. The study, led by Dr. Antonio Bedalov at Fred Hutchinson Cancer Center, aims to reactivate the silenced MeCP2 gene in affected individuals.
A recent study by the American College of Physicians found that physicians spend significantly more time on computer activities than direct patient interaction, taking up about half their workday. This has led to concerns over physician satisfaction, patient education, and increased malpractice risks.
Researchers created a solar still that converts water to vapor very efficiently, with only 12% of available energy lost during evaporation. The device can produce 3-10 liters of water per day, making it an ideal solution for small communities in developing areas and regions affected by natural disasters.
A new study assesses the ally behaviors of college athletes, revealing that female athletes are more likely to identify as LGBT allies. The research also highlights the crucial role that non-LGBT identified athletes play in creating a safe environment for LGBT student-athletes, which can positively impact team cohesion and performance.
Research suggests that people infected with HIV may be more susceptible to developing diabetes, with a prevalence nearly 4% higher than the general public. Despite obesity being a key risk factor, the study found that HIV positive adults are at heightened risk of diabetes at younger ages and in its absence.
The CIViC knowledgebase is an open-access resource that allows anyone to contribute information on cancer mutations. Experts in the field curate and moderate submissions, providing a valuable resource for clinicians to identify important mutations and connect genetic errors with targeted drugs.
Researchers at OHSU developed a method for quickly mapping single cell genomes, expanding the analysis of cancerous tumors and other diseases. This breakthrough enables precise targeting of cancer cells, offering new avenues for personalized medicine.
Astronomers discover five new gamma-ray blazars with massive black holes, challenging current ideas on their formation and growth. The discoveries suggest that these objects could have formed rapidly in the universe's early history.
Dr. McCullough will investigate the effects of social isolation on stroke damage and recovery using miRNAs. The study aims to develop new therapies reducing disability in patients after a stroke.
A new analysis found that over half of US adults consume excessive calories in their daily coffee or tea by adding sugar, cream, or other calorie-dense additives. The study also reveals that drinking black coffee reduces total daily calories by nearly 69 compared to those with added sweeteners.
Researchers developed a new gene-editing method called homology-independent targeted integration (HITI) that efficiently inserts DNA into genes in dividing and non-dividing cells of living rats. The technique uses the CRISPR-Cas9 tool to cut DNA at a specific location, followed by the NHEJ repair pathway for insertion.
Researchers found a naturally occurring hormone, Mullerian Inhibiting Substance (MIS), can halt the development of ovarian follicles, protecting them from chemotherapy-induced damage. This reversible contraceptive method preserves the ovarian reserve and could be applied to modern fertility treatments.
Scientists have developed a new modification to the Gutenberg-Richter law to better predict large earthquakes. This improved model takes into account the finite size of the Earth and provides more accurate estimates of seismic risk. The researchers hope their findings will be useful in evaluating economic losses from potential disasters.
Engaging in brain-stimulating activities like games, crafting, and socializing can lower the risk of mild cognitive impairment (MCI) in older adults. A study of over 1,900 adults found a strong association between mentally stimulating activities and decreased MCI incidence.
A recent study found that more than 100 natural World Heritage sites are being severely damaged by encroaching human activities, with many at risk of irreversible damage. The study highlights the urgent need for conservation efforts to protect these globally important assets.
Researchers at Rice University have developed a new compound of bismuth and carbon nanotubes that improves upon existing cell-tracking agents. The improved Bi4C@US-tubes show up strongly on X-rays taken with computed tomography (CT) scanners, allowing for more efficient tracking of stem cells in the body.
Researchers from Lomonosov Moscow State University discover that Cladocerans originated from the north and spread throughout the Palearctic region via Beringia, a land bridge that closed and reopened multiple times. The study uses molecular genetic analysis to shed light on the evolution and dispersal of these small crustaceans.
A new clinical decision rule developed in Ottawa has been validated to safely take a third of chest pain patients off of heart monitors, freeing up beds for sicker patients. The rule was tested on 1,125 patients and found to accurately predict those who needed to stay on heart monitors with 100% accuracy.
A new species of lobopodian, Ovatiovermis cribratus, has been discovered in the Burgess Shale, providing insights into the ecology and relationship of these ancient creatures. The discovery reveals that strong recurved claws may have allowed them to anchor themselves on hard surfaces and filter food from water.
Scientists have identified a genetic variant that doubles an individual's risk of developing ulcerative colitis and uncovered novel genetic associations to IBD risk. The study provides clues on new drug targets for IBD treatment.
A five-year clinical trial aims to test whether losing weight before pregnancy can reduce the risk of developing gestational diabetes again, with over 250 overweight or obese women participating. The study will also examine perinatal outcomes for mothers and children.
The new Cheyenne supercomputer provides a major tool for advancing understanding of the atmospheric and related Earth system sciences. Scientists will use it to study phenomena such as wildfires and seismic activity, leading to better protecting society from natural disasters.
Researchers discovered that abnormality with gatekeeper cells, which surround blood vessels in the brain, leads to neuron deterioration and possible influence on Alzheimer's disease. Pericyte degeneration restricts blood flow and oxygen supply to active areas of the brain.
Researchers at Johns Hopkins Bloomberg School of Public Health identified a mechanism by which the chikungunya virus controls infection severity. The study found that all alphaviruses and coronaviruses may work in the same way, and that breaking a specific protein bond can prevent viral replication.
A group of scientists is recommending giving the world's nature reserves a makeover to defend not only flora and fauna but also people. The authors propose clusters of nature reserves that would foster connectivity and permit human activity, potentially garnering more local and national support for protected areas.
Researchers now have unprecedented access to space-weather data from 23 GPS satellites, measuring charged particles and their impact on satellite operation. This data helps answer key questions about space weather events, enabling improved forecasting models.
Researchers synthesized mono/di-halogenated coumarins and evaluated their anticancer activity against UACC-62, MCF-7, and PBM cell lines. The test compounds CMRN1-CMRN7 strongly suppressed cell proliferation and induced apoptosis in cancer cells.
Scientists have found that vitamin B12 controls 41 different proteins in a bacterium, regulating folate, ubiquinone, and methionine metabolism. This discovery highlights the importance of B12 in shaping microbial communities and their impact on human health.
Researchers at Jackson Laboratory have identified a newly discovered telomere maintenance mechanism that enables cancer cells to survive and thrive. The study found that most cancer cells reactivate telomerase through TERT transcription, but the exact mechanisms behind this process remained unclear until now.
A microscopic, bag-like sea creature called Saccorhytus, discovered in China, is believed to be the earliest known step on an evolutionary path that led to humans. Its primitive features, including a large mouth and absence of an anus, have provided new insights into human evolution.
A study found that patients with renal dysfunction upon admission are more likely to die while hospitalized and have lower chances of being discharged home. Those with normal kidney function have better short-term outcomes, according to the estimated glomerular filtration rate (eGFR) test.
A new study found that a specific type of heart fat associated with an increased risk of coronary artery calcification, an early sign of heart disease. In postmenopausal women and those with lower estrogen levels, epicardial fat volume was linked to higher risk of heart disease.
Researchers at Boston Children's Hospital have identified a potential therapeutic solution for age-related fibrosis by pinpointing the gene responsible for the condition. Deletion of the PAD4 gene has been shown to curb fibrosis in mice, reducing organ dysfunction and improving heart function.
A new study at the University of Pennsylvania found that people who are more mindful are more likely to change their behavior in response to health messages. Mindful individuals react less negatively to health advice, leading to increased exercise motivation and healthier choices.
A new study from the University of Utah's National Center for Veterans Studies found that a simple intervention, crisis response planning, significantly reduced suicide attempts among active-duty soldiers. The study showed a 75% reduction in suicide attempts compared to contracts for safety.
Researchers have engineered biomimetic structures from mysterious class of disordered proteins, enabling controlled self-assembly and disassembly. This breakthrough will facilitate thorough studies of these proteins and their cellular function, leading to new opportunities for biomedical applications.
Researchers found that storing solar energy for nighttime use increases household annual energy consumption by 8-14% and indirectly raises carbon dioxide emissions. This contradicts the myth that storage is needed to integrate distributed solar power.
A recent UTHealth study found that 78 percent of hospital employees in Houston are overweight or obese. Despite a generally low intake of fruits and vegetables, participants showed significant differences in daily consumption patterns between normal weight, overweight, and obese groups.
Researchers developed a new metric to predict blood clots in the left ventricle, which is more accurate than current methods. The E-wave propagation index can be calculated using standard diagnostic tools and clinical procedures, and has been validated with data from patients who experienced post-heart attack blood clots.
Scientists have discovered a new species of 'unfossilizable' loriciferans, a type of animal so small it was considered impossible to find fossils of. The fossils date back to the late Cambrian Period, around half a billion years ago, and provide insight into early animal evolution and ecosystem diversity.
Researchers have found substantial evidence supporting a holographic explanation for the universe's irregularities, as much as there is for traditional theory of cosmic inflation. A holographic universe is one where all information is contained in a 2D surface on its boundaries.
A University of Queensland-led study warns that over 100 Natural World Heritage Sites are being destroyed by encroaching human activities, with 63% experiencing increased Human Footprint over the past two decades. The most impacted sites were found in Asia, including India and Indonesia, which have suffered significant deforestation.
Researchers at Florida State University have discovered a tumor suppressor protein in fruit flies that can help understand the development of malignant rhabdoid tumors in children. The protein, Snr1, was found to act as a tumor suppressor in an unconventional manner.
School-aged children experience low back pain due to musculoskeletal overuse or trauma, with a correlation between competition level and risk. Preventive measures include pre-season sports conditioning programs and rest, helping reduce injuries and long-term risk of low back pain.
Researchers have discovered that geostrophic balance becomes invalid at smaller scales, making sea level data unreliable for calculating ocean circulation. At high resolution, sea level can accurately calculate circulation in areas with persistent eddies, but not in areas dominated by internal waves.
A new Duke-led analysis reveals that hypoxic dead zones in the Gulf of Mexico drive up the price of large shrimp relative to smaller sizes, causing economic ripples for consumers, fishermen, and seafood markets. The study provides the first evidence linking Gulf hypoxia to economic impacts.
A new study published in Family Practice found that heart failure survival rates have not improved since 1998. The research team analyzed medical records from over 54,000 patients with heart failure and found varying survival rates based on age, gender, health conditions, and blood pressure.
A Brown University study finds that overlearning visual perception tasks strengthens learning and prevents interference, while a longer break between tasks allows for similar performance on both. The study suggests that a temporary shift in neurotransmitter balance is key to the effect of overlearning.
Researchers at Tohoku University identified a new mechanism producing low-energy free electrons from X-ray absorption in matter. The process, known as Electron Transfer Mediated Decay, involves rapid charge redistribution over multiple atomic sites.
Researchers found that areas with high deer numbers tend to have fewer birds that rely on forest shrubs for nesting and hunting. This is because white-tailed deer eat away at these plants, leading to a decline in songbird populations such as the Hooded Warbler and Prairie Warbler.
A major milestone in proteomics research has been achieved with the creation of a vast library of over 330,000 synthetic peptides representing all canonical human proteins. This achievement is expected to enhance protein identification and quantification by alleviating current issues in this field.
Researchers at the University of Exeter found that antibiotics can boost bacterial reproduction in E.coli, leading to increased resistance and faster mutation rates. The study discovered that mutated bacteria reproduced faster than before encountering antibiotics and formed populations three times larger due to mutations.
Researchers found that Ewing sarcoma tumors display unique DNA methylation patterns, which influence gene activity and can lead to different outcomes. The study's results provide insights into the biology of Ewing sarcoma and may lead to personalized therapies with fewer side effects.
Researchers from Lomonosov Moscow State University have found that electrochemical oxygen reduction in lithium-air batteries is plagued by side reactions, limiting recharge cycles. The team identified defect sites in carbon electrodes as a key factor in the reaction's progression.
A recent study among over 1000 colorectal cancer patients found that about 10% carry mutations associated with increased cancer susceptibility. The research recommends genetic testing for all patients to identify these risks and prevent future cases. This expanded approach could also benefit at-risk family members by providing earlier ...
Researchers investigated the use of abatacept, an immune cell modulator, in treating two rare forms of vasculitis: giant cell arteritis (GCA) and Takayasu's arteritis. The studies found promising results for GCA patients, with improved relapse-free survival rates and longer duration of remission compared to placebo.