Scientists have identified seven key proteins in the Zika virus genome that may be responsible for its damaging health effects. The study provides valuable clues for future research on how the virus interacts with human cells and how to develop treatments or prevention strategies.
This review explores the potential of nanoparticle drug delivery systems to improve solubility, permeability, and stability of ophthalmic drugs. The development of these systems may offer a solution to the limitations of traditional topically administered formulations.
Researchers found that brain size evolved at different rates for different species, especially during Homo's evolution, while chewing teeth evolved at similar rates. This challenges the classic view that larger brains led to smaller teeth as a result of tool use.
A study published in the Journal of the American College of Cardiology found that alcohol abuse increases the risk of atrial fibrillation, heart attack and congestive heart failure, similar to other well-established risk factors. The researchers analyzed data from California residents with ambulatory surgery or emergency care and found...
Chelating zinc has been shown to promote survival of neurons in the retina and stimulate repair of damaged nerve fibers. In a mouse model, researchers saw dramatic levels of axon regeneration after using zinc chelators.
Legumain (LGMN) is a cysteine protease over-expressed in tumor microenvironment, facilitating tumour growth and metastasis. Targeting LGMN directly or as a prodrug activator may offer promising cancer management strategies.
A new dopamine hypothesis of schizophrenia proposes a biological basis for the disorder, with dopamine signaling playing a key role in its development. The hypothesis has been revised numerous times since clinical observations first implicated dopamine decades ago.
Children of obese mothers are more likely to fail tests of fine motor skill and social competence, while those born to extremely obese couples also show signs of problem-solving ability delays. The study's findings suggest that paternal obesity also has a significant impact on child development.
Researchers at the University of Rochester Medical Center have developed a new imaging technique that can distinguish individual retinal ganglion cells, which bear most of the responsibility for relaying visual information to the brain. This breakthrough could enable earlier diagnosis and treatment of eye diseases like glaucoma.
Groundbreaking study establishes a timeline for dinosaur incubation, suggesting 3-6 months. Researchers analyzed dinosaur embryo fossils using CT scans and microscopes to determine growth lines on teeth.
A new study reveals that AMPK plays a key role in enhancing insulin's ability to stimulate glucose uptake in muscles after physical activity. This discovery may lead to the development of an 'exercise pill' for people with limited mobility or those who struggle with physical activity.
Research on dinosaur embryos shows that non-avian dinosaurs took 3-6 months to hatch, similar to reptiles. This finding suggests prolonged incubation may have affected their ability to compete with rapidly evolving bird populations, contributing to the mass extinction event.
The American College of Physicians recommends prescribing metformin as the primary treatment for type 2 diabetes when medication is necessary to improve blood sugar levels. Adding a second oral medication to metformin may provide additional benefits, but the cost should be discussed with clinicians and patients.
Research shows chickens possess complex cognitive abilities, including numerical understanding, self-awareness, and referential communication. They also experience emotions like fear, anticipation, and empathy, and demonstrate problem-solving skills in social situations.