A study of 80 people, part of a cohort tracked from prenatal development through midlife, finds that adverse exposure to proinflammatory cytokines in utero is significantly associated with responses to stressful stimuli 45 years later, as adults, with different effects on brain activity and connectivity between men and women prenatally exposed to cytokines.
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Article #20-14464: "Impact of prenatal maternal cytokine exposure on sex differences in brain circuitry regulating stress in offspring 45 years later," by Jill M. Goldstein et al.
MEDIA CONTACT: Jill M. Goldstein, Massachusetts General Hospital, Boston, MA; tel: 617-835-3389; email: < jill_goldstein@hms.harvard.edu >
Proceedings of the National Academy of Sciences