Researchers inserted neurotrophin3 (NT3)-loaded chitosan, a biodegradable material, into the thoracic spinal cord of adult rhesus monkeys with spinal cord injury (SCI), and found that NT3-loaded chitosan promoted long-distance axonal regeneration, neural repair, and motor and sensory functional recovery, findings with potential implications for treating human SCI.
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Article #18-04735: "NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury," by Jia-Sheng Rao et al.
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Proceedings of the National Academy of Sciences