A study in mice finds that ursolic acid, a known anti-inflammatory compound, can promote the repair of myelin in the central nervous system, even in the chronic phases of autoimmune myelin disorders such as multiple sclerosis; the results suggest that ursolic acid may be beneficially combined with current immunomodulatory therapy to treat multiple sclerosis, according to the authors.
Article #20-00208: "A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination," by Yuan Zhang et al.
MEDIA CONTACT: Guang-Xian Zhang, Thomas Jefferson University, Philadelphia, PA; tel: 215-955-8935; e-mail: Guang-Xian.Zhang@jefferson.edu
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Proceedings of the National Academy of Sciences