Bluesky Facebook Reddit Email

Identification of autophagy gene regulation mechanism related to dementia and Lou Gehrig's disease

07.18.19 | Korea Brain Research Institute

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Figure 1
If the TDP-43 protein expression is inhibited in neurons or muscle cells, then autophagy related genes are affected. Credit: @ Korea brain Research Institute

Korea Brain Research Institute (KBRI, President Seo Pan-ghill) announced on July 10 that the international joint research team where Senior Researcher Jeong Yoon-ha and John Hopkins School of Medicine collaborated, found that 'cell autophagy* gene' called ATG7 is related to the onset of frontotemporal dementia and Lou Gehrig's disease.

###

Autophagy

10.1080/15548627.2019.1635379

Additional Media

Figure 3
After inhibiting TDP-43 protein expression in the motor neurons of a mouse, the symptoms of neural degeneration are observed as the mouse grows older. Credit: @ Korea Brain Research Institute
Figure 2
After inhibiting TDP-43 protein expression in the motor neurons of a mouse, the symptoms of ataxia are observed as the mouse grows older. Credit: @ Korea brain Research Institute

Keywords

Autophagy Dementia Gene Regulation

Article Information

Journal
Autophagy
DOI
10.1080/15548627.2019.1635379

Contact Information

Jeong Yoonha
yunha.jeong@kbri.re.kr

How to Cite This Article

APA:
Korea Brain Research Institute. (2019, July 18). Identification of autophagy gene regulation mechanism related to dementia and Lou Gehrig's disease. Brightsurf News. https://www.brightsurf.com/news/LD576MNL/identification-of-autophagy-gene-regulation-mechanism-related-to-dementia-and-lou-gehrigs-disease.html
MLA:
"Identification of autophagy gene regulation mechanism related to dementia and Lou Gehrig's disease." Brightsurf News, Jul. 18 2019, https://www.brightsurf.com/news/LD576MNL/identification-of-autophagy-gene-regulation-mechanism-related-to-dementia-and-lou-gehrigs-disease.html.