Mice that had received lethal injections of either Escherichia coli or Staphylococcus aureus followed by administration of synthetic antimicrobials derived from repurposed toxic peptides of wasp venom exhibited increased leukocyte migration to the infection site and repression of pro-inflammatory cytokines, allowing the infection to clear; mice were monitored for 7 days following treatment, during which time they exhibited reduced bacterial counts and survival rates comparable to those from standard antibiotic treatment, according to the authors.
Article #20-12379: "Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties," by Osmar N. Silva et al.
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Proceedings of the National Academy of Sciences