In an accompanying commentary, Jane Reusch from the University of Colorado Health Sciences Center comments "with the incidence of diabetes and its complications on the rise, these results offer hope for new treatments in the foreseeable future".
TITLE: Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
AUTHOR CONTACT:
Michael A. Brownlee
Albert Einstein College of Medicine, New York, New York, USA.
Phone: 718-430-3636
Fax: 718-430-8570
Email: brownlee@aecom.yu.edu
View the PDF of this article at: http://www.jci.org/cgi/content/full/112/7/1049
ACCOMPANYING COMMENTARY:
Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?
AUTHOR CONTACT:
Jane E. B. Reusch
Veterans Affairs Medical Center, Denver, Colorado, USA.
Phone: 303-399-8020 ext. 2775
Fax: 303-393-5271
Email: jane.reusch@uchsc.edu
Journal of Clinical Investigation