About The Study: Evidence is insufficient for the use of cannabis or cannabinoids for most medical indications. Clear guidance from clinicians is essential to support safe, evidence-based decision-making. Clinicians should weigh benefits against risks when engaging patients in informed discussions about cannabis or cannabinoid use.
Corresponding Author: To contact the corresponding author, Kevin P. Hill, MD, MHS, email khill1@bidmc.harvard.edu .
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(doi:10.1001/jama.2025.19433)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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