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Same plant species, different chemistry

Researchers at Bielefeld University propose a precise and unambiguous way to define chemotypes within a plant species, highlighting genetic and environmental factors influencing chemical composition. This systematic approach aims to improve understanding and practical applications of chemotypes in medicinal plants and agriculture.

SourceBielefeld University·JournalTrends in Plant Science·TypeMeta-analysis·DateSep 29, 2026

One in nine older adults who use cannabis meet criteria for cannabis use disorder

A study from the University of California San Diego School of Medicine found that 11.4% of older adults who used cannabis in the past year met the criteria for cannabis use disorder (CUD). This condition is characterized by a pattern of cannabis use that causes problems or interferes with daily life. The study highlights the importance...

Cannabis linked to earlier onset of psychosis

Researchers found that cannabis users develop psychosis an average of two-and-a-half years earlier than non-users, with the difference increasing with age. The study, which examined 149 studies involving over 71,000 people, suggests a cumulative effect of cannabis use that builds over time.

SourceUniversity of New South Wales·JournalBiological Psychiatry·TypeMeta-analysis·DateAug 18, 2026

Unexpected findings add new insight on cannabis and heart health

Researchers discovered a statistically significant reduction in premature atrial contractions after cannabis inhalation, with no impact on daily activity levels. The findings challenge assumptions about the cardiovascular effects of cannabis and may lead to new approaches for preventing or treating abnormal heart rhythms.

SourceUniversity of California - San Francisco·JournalJournal of the American College of Cardiology·TypeRandomized controlled/clinical trial·DateAug 12, 2026

Therapeutic Use of Cannabis and Cannabinoids

A review of cannabis and cannabinoids' therapeutic use reveals potential health benefits while emphasizing the need for risk assessment and harm reduction strategies. The study highlights the importance of evidence-based guidelines for safe and effective treatment.

SourceJAMA Network·JournalJAMA·DateAug 6, 2026

THC, the cannabis active ingredient, can put an end to trauma-related nightmares

Researchers at Charité – Universitätsmedizin Berlin investigated the use of THC to alleviate PTSD-related nightmares. The study found that more than half of participants responded to treatment, with over a third experiencing complete disappearance of nightmares. The medication was also well-tolerated, with moderate side effects reported.

SourceCharité - Universitätsmedizin Berlin·JournalNature Medicine·DateAug 5, 2026

Cannabis branding may appeal to youth despite regulations, study finds

A Washington State University study found that cannabis packaging design features, particularly branding elements, can attract underage consumers, raising questions about existing regulations. Participants preferred colorful logos, bold typography, and images resembling familiar foods over warning labels and nutritional information.

SourceWashington State University·JournalInternational Journal of Drug Policy·DateJun 16, 2026

Bradley Hospital study shows teen cannabis use is linked to differences in developing brain regions

A new study from Bradley Hospital researchers shows that cannabis use during adolescence is associated with reduced dopamine-related neurophysiology and altered reward processing. The study found that teens who repeatedly used cannabis showed signs of reduced tissue iron levels in brain regions involved in motivation and reward.

SourceBrown University Health·JournalNeuropsychopharmacology·DateJun 4, 2026

Cannabis use does not lower testosterone

A new study by UNIGE and SCAHT reveals that cannabis use is associated with an increase in testosterone levels, particularly in the testes. However, this increase does not appear to have a direct link to fertility, and further research is needed to determine potential long-term effects.

SourceUniversité de Genève·JournalCommunications Medicine·TypeNews article·DateMay 28, 2026

Cannabis and tobacco co-use increases psychosis chances in high-risk cohorts: Study

A new study published in Nature Mental Health found that using cannabis and tobacco together significantly increases the risk of developing psychotic disorders like schizophrenia among those considered high risk. The study analyzed data from over 1,000 participants and found that co-use was associated with a nearly threefold increased ...

SourceVanderbilt University Medical Center·JournalNature Mental Health·DateMay 12, 2026

Research Alert: Teens view cannabis as less harmful than alcohol, vapes and cigarettes

A recent study analyzing data from two California school surveys found that adolescents consistently perceive cannabis as the least harmful substance among their peers. The study, which examined responses from over 175,000 students, also identified age, experience, and social environment as factors influencing teens' perceptions of can...

SourceUniversity of California - San Diego·JournalDrug and Alcohol Dependence·DateMay 6, 2026

Cannabis microdosing more common than psychedelics among US adults, national survey finds

A national survey found that millions of US adults have microdosed substances like cannabis, psilocybin, LSD, and MDMA, with cannabis being the most commonly microdosed. The study also revealed patterns tied to mental health and policy environments, suggesting that changes in drug policy may influence access to these substances.

SourceUniversity of California - San Diego·JournalAmerican Journal of Preventive Medicine·DateMay 4, 2026

No evidence to suggest medicinal cannabis is effective for depression, anxiety or PTSD: research

A comprehensive review of 54 randomized controlled trials found no evidence that medicinal cannabis is effective in treating anxiety, depression, or PTSD. However, the study suggests that medicinal cannabis may be beneficial for certain conditions, such as reducing seizures associated with epilepsy and managing pain.

SourceUniversity of Sydney·JournalThe Lancet Psychiatry·TypeMeta-analysis·DateMar 16, 2026

Cannabis compounds show promise in fighting fatty liver disease

Researchers discovered that CBD and CBG can significantly reduce liver fat and improve metabolic health by creating a backup energy reserve and restoring cellular cleaning crews. These compounds also showed promising effects on treating metabolic diseases, including reducing body fat mass and improving insulin sensitivity.

SourceThe Hebrew University of Jerusalem·JournalBritish Journal of Pharmacology·TypeExperimental study·DateMar 5, 2026

Cannabis essential oils unlock how camphor repels mosquitoes - new study

Researchers have identified the specific smell receptor that causes mosquitoes to avoid borneol, a natural compound found in camphor tree oils. Activating this receptor triggers a neural pathway leading to avoidance behavior, offering potential strategies for designing more targeted and effective mosquito repellents.

SourceThe Hebrew University of Jerusalem·JournalNature Communications·TypeExperimental study·DateFeb 24, 2026

‘The munchies’ are real and could benefit those with no appetite

A study by Washington State University and the University of Calgary found that cannabis use increases appetite in humans and rodents alike, regardless of food consumption or body mass index. The researchers discovered that the brain's cannabinoid receptors play a key role in stimulating hunger, paving the way for future treatments.

SourceWashington State University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 19, 2026

UT Health San Antonio research shows Alzheimer’s prevention potential in pairing cannabis ingredient, anti-inflammatory drug

A new study led by Dr. Chu Chen suggests that combining THC with celecoxib may improve cognition and reduce Alzheimer's-related brain pathology in mice. The combination produced better outcomes than low-dose THC alone, including improved learning and memory performance and reduced markers of neuroinflammation.

SourceThe University of Texas at San Antonio Health Science Center·JournalAging and Disease·TypeExperimental study·DateJan 28, 2026

No clear evidence that cannabis-based medicines relieve chronic nerve pain

An updated Cochrane review of 21 clinical trials involving over 2,100 adults found no high-quality evidence that cannabis-based medicines reduce neuropathic pain more than placebo. Small improvements were reported by patients using products with both THC and CBD, but these changes were not clinically meaningful.

SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateJan 18, 2026

The stop-smoking medication varenicline may also work for cannabis use disorder

A new study found that varenicline, a medication used to quit smoking, can help men with cannabis use disorder reduce their cannabis use. However, the same treatment showed no significant effect on female participants. Women who received varenicline reported higher withdrawal and craving scores and lower medication adherence compared t...

SourceSociety for the Study of Addiction·JournalAddiction·TypeRandomized controlled/clinical trial·DateJan 15, 2026

Smartphone-based interventions show promise for reducing alcohol and cannabis use: New research

New research suggests that mobile health interventions tailored to individual needs can reduce harms associated with heavy drinking and cannabis use. Studies demonstrate the effectiveness of personalized feedback and protective behavioral strategies in reducing substance use risks, paving the way for innovative digital interventions.

SourceJournal of Studies on Alcohol and Drugs·JournalJournal of Studies on Alcohol and Drugs·TypeExperimental study·DateJan 12, 2026