A recent study by Florida Atlantic University found that US adolescents with cannabis use disorder have low treatment completion rates, ranging from 34.2% to 33.8%. The most common reasons for not completing treatment were dropping out, transferring facilities, and being terminated. Adolescents who began using cannabis at a younger age...
A recent study published in JAMA Otolaryngology–Head & Neck Surgery found an association between cannabis use disorder and benign salivary gland tumors. The researchers call for further prospective research to confirm this association and understand the relationship between cannabis use and these tumors.
A longitudinal cohort study found that recreational cannabis legalization was associated with increased cannabis and electronic nicotine delivery systems use, but not a significant increase in cigarette use. The study suggests that commercialization policy should be closely monitored as retail cannabis expands.
Researchers investigate cannabis-based treatment to improve quality of care for hospice-eligible patients with dementia. A clinical trial will test T2:C100, a drug containing THC and CBD, to determine its effectiveness in reducing agitation.
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A study by University of Pittsburgh researchers found that anxiety diagnoses became the most common in Pennsylvania's medical cannabis program after being added, dropping chronic pain and PTSD diagnoses. The team analyzed data from 1,730,600 certifications issued from November 2017 to December 2023.
A study by University of Colorado at Boulder found that nearly half of cannabis flower products contain more THC than their labels claim, while concentrates tend to be accurately labeled. The study emphasizes the importance of accurate labeling in the industry.
A landmark survey of over 5,000 Californians reveals significant gaps in knowledge about cannabis use and its impacts. The study found that many users seek symptom relief, while few consult their doctors for advice on safe use practices.
A randomized clinical trial found that cannabidiol (CBD) administration led to liver enzyme level elevations in 5.6% of participants and potential drug-induced liver injury in 4.9%. Hepatic enzymes returned to normal within weeks after discontinuation. Further research is needed on CBD's long-term effects and safety.
Law enforcement use subjective tactics to detect marijuana impairment, but these methods have limited scientific basis. Scientists must get involved to develop reliable tools, and funding from legal marijuana sales could support research. A new perspective calls for a more evidence-based approach to road safety.
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A survey study of California adolescents found exposure to e-cigarette or cannabis posts was associated with increased use of these substances. The study suggests that improving social media community guidelines and policy attention may help prevent youth substance use.
A controlled clinical trial found that two-thirds of participants showed behavioral improvements with CBD treatment, highlighting its potential benefits. However, the study also revealed a significant placebo effect, emphasizing the need for further research to fully understand CBD's therapeutic potential.
A study found that cannabis use among older adults in the US has reached a new high, with 7% of adults aged 65 and over reporting current use. The profile of those who use cannabis has changed, with pronounced increases in use by college-educated, married, female, and higher-income individuals.
A recent study published in the American Journal of Preventive Medicine reveals a significant correlation between socioeconomically disadvantaged areas and increased cannabis retailer presence. Neighborhoods with higher concentrations of low-income Black residents had 2.53 times more cannabis retailers than high-income predominantly Wh...
Prevalence of current cannabis use rose significantly among adults aged 65+, particularly those with higher incomes. Adults with initial lower cannabis use rates now exhibit the highest prevalence by 2023.
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Researchers created the most comprehensive genetic atlas of cannabis, revealing unprecedented diversity and untapped opportunity in this foundational agricultural species. The study sets the stage for transformative advances in cannabis-based agriculture, medicine, and industry.
A recent study found that cannabis use during pregnancy can alter DNA methylation in placental tissue, which may impact child behavioral outcomes. The research, conducted by Dr. Emma C. Johnson, suggests a potential link between prenatal cannabis exposure and gene regulation in the developing fetus.
A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
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A cross-sectional study found a strong association between chronic cannabis use and endothelial dysfunction. The findings suggest that THC may contribute to the development of cardiovascular disease through distinct mechanisms, similar to tobacco smoking.
A new study finds that cannabis use disorder diagnoses rose substantially across all age groups, race/ethnicity, and comorbidity subgroups nationwide from 2000 to 2022. People living with HIV experienced the greatest relative increase in CUD diagnoses, particularly among older adults.
New research reveals that recreational cannabis legalization leads to significant reductions in prescription drug claims per enrollee, with annual savings of $34-$42 in small group insurance markets. However, the study found no similar effect in large group insurance markets.
A cross-sectional study found that more than one-third of veterans aged 65-84 who used cannabis in the past 30 days had a cannabis use disorder. Routine health screening for cannabis use is necessary to identify older adults with cannabis use. Frequent and inhaled cannabis use was associated with higher odds of any cannabis use disorder.
A randomized controlled trial in Switzerland found that legal access to cannabis decreases problematic consumption, especially among individuals using other substances. After two years, participants showed significant improvements in mental state.
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A new study found that cannabis-related hospital visits increased by 20% in Arizona between 2016 and 2021, with nearly eight times more patients having a primary diagnosis of a mental health disorder. The study suggests easier access to cannabis may be partly responsible for the trend.
A recent study published in JAMA Pediatrics found that prenatal cannabis use is associated with an increased risk of preterm birth and low birth weight. The research also suggests a potential link between cannabis use during pregnancy and smaller-than-average newborns.
A systematic review found a moderate risk of preterm birth, low birth weight, and infant death associated with cannabis use during pregnancy. Researchers recommend reducing cannabis use as a harm-reduction approach to mitigate risks.
Researchers at the University of California San Diego School of Medicine have found that high cannabis use is associated with increased mortality in colon cancer patients. The study analyzed data from over 1,000 patients and found a significant link between heavy cannabis use and reduced survival rates.
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A serial cross-sectional study found that legalization of cannabis edibles and extracts was associated with an increase in edible cannabis use, cannabis smoking, and overall cannabis use among adolescents. The study highlights the need for stricter policy measures to curb adolescents' access to cannabis edibles and extracts.
A new study found that individuals with hospital visits due to cannabis use were at a 23% and 72% greater risk of new dementia diagnoses within five years compared to those with ED visits or the general population. The study included 6 million adults aged 45 and older from Ontario, Canada.
A recent study found that people who use cannabis while drinking alcohol may experience fewer negative effects, potentially fueling more drinking. The study examined 6,334 data entries and found that participants perceived fewer negative impacts when using cannabis simultaneously with alcohol.
Researchers found individuals with cannabis use disorder exhibit increased dopamine levels in the brain, a key factor in psychosis. This study suggests that regular cannabis use is linked to signs of increased dopamine activity.
Researchers have found that people with cannabis use disorder have elevated dopamine levels in a brain region associated with psychosis. This could explain why frequent cannabis use increases the risk of hallucinations and delusions. The study's findings may help doctors educate patients about the potential risks of frequent cannabis u...
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Dr. Romina Mizrahi's PET-based neuroimaging sheds light on brain workings, integrating genetics, environment and imaging to understand psychiatric illness as a complex biological puzzle. She advocates for precision psychiatry paradigm with customized treatments based on molecular profiles, and calls for diversity in academic leadership.
The American College of Physicians issues Best Practice Advice for managing chronic noncancer pain with cannabis or cannabinoids. For most patients, common treatments should be recommended first due to limited evidence and known harms associated with cannabis and cannabinoid products.
A new pilot study found that medically supervised cannabis use helped manage pain, anxiety, and sleep issues in people recovering from substance use challenges. Participants reported reduced cravings and improved mental health and sleep quality.
Patients prescribed medicinal cannabis in Australia showed long-term improvements in overall health-related quality of life, fatigue, and sleep disturbance. The study, which recruited over 2,300 participants, also found improvements in anxiety, depression, insomnia, and pain for those with corresponding conditions.
Between 2015-2020, 893,430 pregnant women were identified with a cannabis use disorder diagnosis, resulting in 1,058,448 total pregnancies. The cumulative prevalence of CUD diagnosis was 0.26%. Clinicians are well-positioned to intervene but may lack structural support due to fear of legal repercussions and underestimated diagnoses.
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Recent studies published in Behavioral Medicine and Alcohol explore the link between pain and substance use among emerging adults. Individuals with moderate to severe pain are more likely to start using cannabis over a four-year period, often taking it up earlier, and are also at higher risk of mixing it with alcohol.
A study by the University of the Basque Country has detected potential biomarkers in the blood that could help predict the risk of developing schizophrenia due to cannabis use. The researchers found significant differences in fatty acid content between cannabis users, individuals with schizophrenia, and those with dual diagnoses.
A recent study by Arizona State University researchers found high levels of Fusarium mycotoxins in illicit cannabis samples seized in Arizona and California, posing potential health risks to consumers. The study highlights the unregulated nature of black-market cannabis and the need for further research into its health impacts.
Scientists at the University of South Australia have developed a phospholipid complex to improve cannabidiol's effectiveness in treating epilepsy, multiple sclerosis, and other neurodegenerative diseases. The new formula increases cannabidiol's solubility by up to six times and improves its absorption in the gastrointestinal tract.
Two new studies have found a substantial link between cannabis use and an increased risk of heart attack. The studies, one retrospective and one meta-analysis, pooled data from over 4.6 million people, showing that cannabis users under the age of 50 were six times more likely to suffer a heart attack than non-users.
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Research at the University of Arizona Health Sciences found that certain terpenes in Cannabis sativa are effective at relieving post-surgical and fibromyalgia pain in preclinical models. Terpenes have been shown to provide significant pain relief in mouse models, with geraniol providing the most significant level of pain relief.
Researchers developed a custom-designed compound that mimics natural cannabis molecules to alleviate chronic pain without psychoactive side effects. The modified synthetic cannabinoid compound showed promise as a nonaddictive pain reliever, offering prolonged relief and minimizing tolerance.
A recent study published in Psychiatry Research found that children exposed to their mother's cannabis use during pregnancy and after birth are three times more likely to develop behavioural problems. The research analysed data from over 222,600 Australian mothers and children, revealing a significant increase in the risk of childhood ...
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Oregon Health & Science University researchers found that maternal THC consumption can decrease lung volume in developing fetuses and alter lung gene expression. This study is the first to examine the effects of prenatal cannabis exposure on offspring respiratory health, raising concerns for potential long-term impacts.
A study by Columbia University found that unlicensed dispensaries in New York City often lack effective age verification processes, allowing youth access to high-potency cannabis. Licensed retailers, on the other hand, were more likely to follow state regulations and post certificates of analysis for their products.
A recent study published in CANCER found that pain is associated with a greater likelihood of tobacco and cannabis use among cancer survivors. Pain also exacerbates treatment-related side effects and worsens health outcomes.
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Residents of Ontario with cannabis use disorder had a significantly higher risk of death compared to the general population. The findings highlight the importance of addressing cannabis use disorders, especially as global trends toward cannabis legalization continue.
A new study published in the Journal of Studies on Alcohol and Drugs suggests that mandatory warning signs at cannabis dispensaries may not be effective in deterring pregnant users. In fact, many participants reported distrust towards the content of the warnings, viewing them as stigmatizing or negative. The researchers interviewed 34 ...
Researchers have discovered how a CBD compound can bind to cannabinoid receptors, mitigating the negative effects of THC on pain management while preserving its benefits. The study opens new avenues for harnessing THC's beneficial effects with reduced side effects.
A new study from McMaster University reveals that oral cannabis use during pregnancy can disrupt fetal growth, nutrient delivery, and development of the placenta. The research also found potential long-term consequences on offspring behavior and learning ability.
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A new study found that cannabis use disorder is increasingly associated with new schizophrenia cases in Ontario, with the proportion rising from 4% to 10%. The trend has tripled over the past 17 years, with heavy cannabis use linked to worsening symptoms and increased risk of psychosis.
A recent study published in JAMA Network Open found that heavy cannabis users exhibited reduced brain activity during working memory tasks, associated with worse performance. Abstaining from cannabis before cognitive tasks may help improve performance.
A study of young adults found that heavy lifetime cannabis use is associated with negative outcomes on working memory tasks. These findings suggest potential long-lasting effects of cannabis use on brain function.
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Researchers found that households with reported in-home cannabis smoking had a child with detectable cannabis biomarker levels five times higher than those without in-home smoking. Reducing in-home cannabis smoking could substantially reduce children's exposure to toxic chemicals.
A cross-sectional study found that children exposed to secondhand cannabis smoke at home have significantly higher urinary cannabinoid biomarker levels, indicating increased exposure to toxic and carcinogenic chemicals. Reducing in-home cannabis smoking can substantially reduce child exposure to these harmful substances.
A recent study published in JAMA Psychiatry found that medically recommended cannabis use is associated with a higher prevalence of cannabis use disorder and more frequent use among US adults. The study suggests that medically recommended cannabis may not be effective in reducing addiction risk compared to nonmedical use.
Researchers developed an Index of Cannabis Equivalence (ICE) to establish standardized cannabis dosing guidelines. The study found that two puffs from a joint, pipe, or vaporizer equal one bong hit in terms of psychoactive effects.
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A new study at Columbia University Mailman School of Public Health found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. Decreases in opioid outcomes were observed among people reporting cannabis use but not when both medical and recreational use laws existed.
A longitudinal cohort study found that state cannabis legalization is associated with increased cannabis use disorder and poisoning diagnoses. Communities with increased access to cannabis may experience increased healthcare use and costs due to these rising diagnoses.