Articles tagged with Cannabis
A team of UNLV researchers has engineered a new class of cannabidiol (CBD)-like medicines that show powerful seizure-reducing effects. The caraway-seed derived therapies offer a safer and more effective treatment for childhood seizure disorders than existing frontline therapies.
A large genetic study found associations between cannabis use and various traits, including psychiatric disorders, cognitive measures, and physical health problems. The study identified two genes, CADM2 and GRM3, linked to lifetime cannabis use and frequency of use.
The BGU-RADAR Center, in collaboration with leading US universities, has developed a consensus statement on essential knowledge and skills for integrating medical cannabis into clinical practice responsibly. The statement outlines key competencies for healthcare providers to counsel patients effectively on medical cannabis use.
Individuals with psychosis reported a large increase in current cannabis use following legalization, exceeding previous estimates for the general population. This finding highlights the need for policymakers to consider the potential health impacts of cannabis use on individuals with psychosis.
A six-year analysis of coroner records from Ohio reveals that over 40% of drivers who died in fatal crashes tested positive for active THC in their blood, with average levels exceeding most state impairment limits. The study found no change in THC positivity before or after the legalization of recreational cannabis.
Pediatric marijuana ingestions have increased by over 1,000% in the past seven years, primarily due to increased access to cannabis products during the COVID-19 pandemic. Children under 5 years old are most affected, with Black children and those from publicly insured households being disproportionately exposed.
A nationwide app called CHAMPS aims to support safer cannabis consumption among young adults who've experienced a psychotic episode. The pilot study found the app to be well-regarded and can be integrated into real clinical environments.
Researchers manipulated the endocannabinoid signaling system in prenatal mice, leading to altered gene expression, neural properties, and social interaction deficits. This work suggests that prenatal manipulation of this system may lead to neuropsychiatric conditions, particularly those involving social deficits.
A new study found that inhaling marijuana daily is associated with a 44% increased chance of developing asthma. Experts say people should avoid inhaling cannabis to reduce the risk of chronic lung disease. The study's authors emphasize the need for clearer messages about the risks of cannabis use.
A new survey found that the high cost of legal cannabis products is a significant barrier for many participants, while access to unbiased information helps people avoid illicit products. Understanding patients' difficulties in accessing safe products can guide strategies to make the process easier.
A new study analyzing real-world data from over 4 million adults found that cannabis users face almost four times the risk of developing type 2 diabetes within five years compared to non-users. The study suggests that long-term metabolic effects of cannabis use may be linked to insulin resistance and unhealthy dietary behaviors.
Researchers found no indication of reduced driving ability in frequent cannabis users who had abstained for at least two days. The study's findings suggest that relying on blood THC concentrations to assess impairment is not justified for regular cannabis users.
A 12-week high-intensity interval training intervention did not improve hippocampal integrity or cognitive/mental health impairments, but reduced cannabis craving. Regular physical exercise may be a potential strategy for managing cannabis use disorder.
A new longitudinal study by York University found that young adults using both substances in times of high stress and emotional distress reported more negative life consequences. The study suggests that understanding combined use can help young adults mitigate the risk and seek healthier coping mechanisms.
A study by University of California San Diego researchers found that delta-8 THC use is most common in states where marijuana is illegal, with 10.9% of adults reporting lifetime use. The study suggests that gaps in cannabis policy may be steering people towards less-regulated substances.
Insomnia patients taking cannabis-based medical products reported significant improvements in sleep quality, anxiety, and pain over 18 months. The study found sustained benefits with minimal side effects, suggesting potential for medical cannabis as an option for conventional treatments.
Research from King's College London and University of Bath found that people who self-medicate with cannabis for physical or mental discomfort are more likely to develop paranoia and anxiety. The study also discovered a link between childhood trauma and increased paranoia scores, which is exacerbated by cannabis use.
A systematic review found that high-concentration delta-9-tetrahydrocannabinol (THC) cannabis products are linked to unfavorable mental health outcomes, including psychosis and schizophrenia. The review of 99 studies suggests that higher THC concentrations increase the risk for adverse mental health effects.
Researchers at the University of Oklahoma are conducting a first-of-its-kind study to investigate the effect of cannabis use on facial wound healing in head and neck cancer patients. The study aims to determine whether cannabis smoking negatively affects wound healing, with potential implications for other types of surgery and conditions.
Increased cannabis potency has been linked to a rise in schizophrenia cases. THC content has increased by 5 times since the 2000s, contributing to this correlation.
A study by Columbia University researchers found that unlicensed cannabis products often lack required health warnings and safety features, while also using appealing packaging to attract minors. The study highlights a need for coordinated regulation to ensure product safety and prevent misleading marketing.
A study by Texas A&M University found that cannabis use is more common among non-Hispanic Black men with chronic health issues, particularly those with pain, stress and depression. The research suggests a two-way relationship between cannabis use and worsening physical and mental health.
A new study found that young adults using high-strength cannabis in California tend to consume more and experience greater symptoms of cannabis use disorder. The study, which surveyed over 400 participants, showed a significant association between THC potency and cannabis consumption frequency and quantity.
A recent study by researchers at University of California San Diego School found that individuals with cannabis use disorder are more than three times more likely to develop oral cancer within five years. The study highlights the potential long-term health risks associated with problematic cannabis use and emphasizes the need for furth...
A recent study by Florida Atlantic University found that US adolescents with cannabis use disorder have low treatment completion rates, ranging from 34.2% to 33.8%. The most common reasons for not completing treatment were dropping out, transferring facilities, and being terminated. Adolescents who began using cannabis at a younger age...
A pioneering international survey found that cannabis and psychedelics were best rated for alleviating eating disorder symptoms by respondents who self-medicated with these non-prescribed drugs. The research also revealed promising avenues for future clinical trials of psilocybin in treating anorexia nervosa.
A recent study published in JAMA Otolaryngology–Head & Neck Surgery found an association between cannabis use disorder and benign salivary gland tumors. The researchers call for further prospective research to confirm this association and understand the relationship between cannabis use and these tumors.
A longitudinal cohort study found that recreational cannabis legalization was associated with increased cannabis and electronic nicotine delivery systems use, but not a significant increase in cigarette use. The study suggests that commercialization policy should be closely monitored as retail cannabis expands.
Researchers investigate cannabis-based treatment to improve quality of care for hospice-eligible patients with dementia. A clinical trial will test T2:C100, a drug containing THC and CBD, to determine its effectiveness in reducing agitation.
A randomized clinical trial found that cannabidiol (CBD) administration led to liver enzyme level elevations in 5.6% of participants and potential drug-induced liver injury in 4.9%. Hepatic enzymes returned to normal within weeks after discontinuation. Further research is needed on CBD's long-term effects and safety.
A study by University of Pittsburgh researchers found that anxiety diagnoses became the most common in Pennsylvania's medical cannabis program after being added, dropping chronic pain and PTSD diagnoses. The team analyzed data from 1,730,600 certifications issued from November 2017 to December 2023.
A study by University of Colorado at Boulder found that nearly half of cannabis flower products contain more THC than their labels claim, while concentrates tend to be accurately labeled. The study emphasizes the importance of accurate labeling in the industry.
A landmark survey of over 5,000 Californians reveals significant gaps in knowledge about cannabis use and its impacts. The study found that many users seek symptom relief, while few consult their doctors for advice on safe use practices.
Law enforcement use subjective tactics to detect marijuana impairment, but these methods have limited scientific basis. Scientists must get involved to develop reliable tools, and funding from legal marijuana sales could support research. A new perspective calls for a more evidence-based approach to road safety.
A survey study of California adolescents found exposure to e-cigarette or cannabis posts was associated with increased use of these substances. The study suggests that improving social media community guidelines and policy attention may help prevent youth substance use.
A controlled clinical trial found that two-thirds of participants showed behavioral improvements with CBD treatment, highlighting its potential benefits. However, the study also revealed a significant placebo effect, emphasizing the need for further research to fully understand CBD's therapeutic potential.
A study found that cannabis use among older adults in the US has reached a new high, with 7% of adults aged 65 and over reporting current use. The profile of those who use cannabis has changed, with pronounced increases in use by college-educated, married, female, and higher-income individuals.
A recent study published in the American Journal of Preventive Medicine reveals a significant correlation between socioeconomically disadvantaged areas and increased cannabis retailer presence. Neighborhoods with higher concentrations of low-income Black residents had 2.53 times more cannabis retailers than high-income predominantly Wh...
Prevalence of current cannabis use rose significantly among adults aged 65+, particularly those with higher incomes. Adults with initial lower cannabis use rates now exhibit the highest prevalence by 2023.
Researchers created the most comprehensive genetic atlas of cannabis, revealing unprecedented diversity and untapped opportunity in this foundational agricultural species. The study sets the stage for transformative advances in cannabis-based agriculture, medicine, and industry.
A recent study found that cannabis use during pregnancy can alter DNA methylation in placental tissue, which may impact child behavioral outcomes. The research, conducted by Dr. Emma C. Johnson, suggests a potential link between prenatal cannabis exposure and gene regulation in the developing fetus.
A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
A cross-sectional study found a strong association between chronic cannabis use and endothelial dysfunction. The findings suggest that THC may contribute to the development of cardiovascular disease through distinct mechanisms, similar to tobacco smoking.
A new study finds that cannabis use disorder diagnoses rose substantially across all age groups, race/ethnicity, and comorbidity subgroups nationwide from 2000 to 2022. People living with HIV experienced the greatest relative increase in CUD diagnoses, particularly among older adults.
New research reveals that recreational cannabis legalization leads to significant reductions in prescription drug claims per enrollee, with annual savings of $34-$42 in small group insurance markets. However, the study found no similar effect in large group insurance markets.
A cross-sectional study found that more than one-third of veterans aged 65-84 who used cannabis in the past 30 days had a cannabis use disorder. Routine health screening for cannabis use is necessary to identify older adults with cannabis use. Frequent and inhaled cannabis use was associated with higher odds of any cannabis use disorder.
A randomized controlled trial in Switzerland found that legal access to cannabis decreases problematic consumption, especially among individuals using other substances. After two years, participants showed significant improvements in mental state.
A new study found that cannabis-related hospital visits increased by 20% in Arizona between 2016 and 2021, with nearly eight times more patients having a primary diagnosis of a mental health disorder. The study suggests easier access to cannabis may be partly responsible for the trend.
A recent study published in JAMA Pediatrics found that prenatal cannabis use is associated with an increased risk of preterm birth and low birth weight. The research also suggests a potential link between cannabis use during pregnancy and smaller-than-average newborns.
A systematic review found a moderate risk of preterm birth, low birth weight, and infant death associated with cannabis use during pregnancy. Researchers recommend reducing cannabis use as a harm-reduction approach to mitigate risks.
Researchers at the University of California San Diego School of Medicine have found that high cannabis use is associated with increased mortality in colon cancer patients. The study analyzed data from over 1,000 patients and found a significant link between heavy cannabis use and reduced survival rates.
A serial cross-sectional study found that legalization of cannabis edibles and extracts was associated with an increase in edible cannabis use, cannabis smoking, and overall cannabis use among adolescents. The study highlights the need for stricter policy measures to curb adolescents' access to cannabis edibles and extracts.
A new study found that individuals with hospital visits due to cannabis use were at a 23% and 72% greater risk of new dementia diagnoses within five years compared to those with ED visits or the general population. The study included 6 million adults aged 45 and older from Ontario, Canada.
A recent study found that people who use cannabis while drinking alcohol may experience fewer negative effects, potentially fueling more drinking. The study examined 6,334 data entries and found that participants perceived fewer negative impacts when using cannabis simultaneously with alcohol.
Researchers found individuals with cannabis use disorder exhibit increased dopamine levels in the brain, a key factor in psychosis. This study suggests that regular cannabis use is linked to signs of increased dopamine activity.
Researchers have found that people with cannabis use disorder have elevated dopamine levels in a brain region associated with psychosis. This could explain why frequent cannabis use increases the risk of hallucinations and delusions. The study's findings may help doctors educate patients about the potential risks of frequent cannabis u...
Dr. Romina Mizrahi's PET-based neuroimaging sheds light on brain workings, integrating genetics, environment and imaging to understand psychiatric illness as a complex biological puzzle. She advocates for precision psychiatry paradigm with customized treatments based on molecular profiles, and calls for diversity in academic leadership.
A new pilot study found that medically supervised cannabis use helped manage pain, anxiety, and sleep issues in people recovering from substance use challenges. Participants reported reduced cravings and improved mental health and sleep quality.
The American College of Physicians issues Best Practice Advice for managing chronic noncancer pain with cannabis or cannabinoids. For most patients, common treatments should be recommended first due to limited evidence and known harms associated with cannabis and cannabinoid products.
Patients prescribed medicinal cannabis in Australia showed long-term improvements in overall health-related quality of life, fatigue, and sleep disturbance. The study, which recruited over 2,300 participants, also found improvements in anxiety, depression, insomnia, and pain for those with corresponding conditions.