Researchers identified a targeted drug that blocks a specific genetic pathway to reverse tumor-driving cellular interactions, potentially restoring DNA function and benefiting patients with synovial sarcoma. The study's findings endorse a promising strategy to improve outcomes for this rare but deadly cancer.
The University of Hong Kong has launched the Hong Kong Institute for Astronomy and Astrophysics (HKIAA), uniting astronomers across Hong Kong and the Greater Bay Area. The institute aims to bolster Hong Kong's role as a global hub for scientific excellence, attracting top talent and fostering international collaborations.
Researchers have identified two new species of Pinocchio chameleons in Madagascar, reclassifying the long-known Calumma nasutum as part of a complex that includes the newly described Calumma pinocchio and Calumma hofreiteri. Genetic analysis revealed that the nose chameleons' snout shape can change quickly.
A study of nearly 4,000 middle-aged adults found that combined sleep apnea and insomnia increase the risk of uncontrolled hypertension. The strongest risk factor was identified as the combination of both conditions, with 10.2% of participants experiencing high blood pressure.
A study by HKUMed identified a critical gut bacterium disrupting immune system function in liver cancer patients, leading to treatment resistance. Modifying gut microecology or supplementing with key metabolites may enhance immunotherapy effectiveness in the future.
The 'Cancer Immunology Data Engine' platform integrates clinical outcomes from 5,957 cancer patients worldwide with comprehensive multi-omics datasets covering 17 cancer types. Researchers can explore and analyse clinical trial data in depth, accelerating advances in cancer immunotherapy research.
A new survey shows that nearly half of US consumers plan to spend about $100 on their main holiday meal this year. The Physicians Committee for Responsible Medicine offers strategies to slash holiday meal costs by half, including a plant-based holiday spread that can be made for under $50.
A long-term study found that prescribed burning significantly enhances the net productivity of plots with three treatments, increasing carbon sequestration capacity while maintaining large fire-resistant trees. This approach can help reduce wildfire hazard and support California's goal of net zero carbon by 2045.
Researchers at HKUMed used big data to identify rare side effects of antipsychotic medications, including increased gynaecological cancer risk and infection risk among clozapine users. The findings provide evidence for safer global prescribing and inform clinical guidelines and policy.
A recent study found that regularizing bedtime without changing sleep duration can significantly lower blood pressure in individuals with hypertension. Participants who stuck to a consistent bedtime for two weeks experienced drops in their blood pressure, particularly during nighttime hours.
Dental teams can identify hypertension and cardiovascular disease risk through blood pressure screenings in routine care visits. The American Heart Association's Healthy Smiles, Healthy Hearts initiative provides standard blood pressure screening and referral guides, empowering dentists to connect patients with primary care.
The study reveals that the exciton diffusion coefficient is approximately three times greater in η-phase than β-phase nanofibers, indicating longer-range energy transport. The findings provide new design principles for achieving higher efficiency in organic photoenergy conversion and optoelectronic devices.
The conference aimed to foster transformative collaboration between the Greater Bay Area (GBA) and ASEAN countries. Key findings highlighted the importance of higher education institutions in creating shared prosperity and peace through proactive collaboration.
A University of Sydney-led study found that 42% of Australian adults experienced traumatic events as children, leading to a 50% higher risk of developing mental health or substance use disorders. Childhood trauma is linked to chronic physical health conditions and can have lifelong consequences.
A meta-analysis of 268 cohort studies covering over 10 million people found that depression doubles mortality rates and increases suicide risk 10-fold. Timely and effective treatment can significantly reduce these risks, with antidepressant medication lowering overall mortality risk by approximately 20%.
A new study finds that floating solar panel systems can have varying effects on aquatic ecosystems depending on the reservoir's depth, circulation dynamics, and fish species. The cooling effect of the water can boost panel efficiency, but increased variability in habitat suitability for aquatic species is also observed.
Researchers developed a 3D lattice iontronic sensor that accurately detects sophisticated tactile interactions by linearizing both electrical responses and mechanical behaviors. The sensor, comprising a hydrogel lattice encapsulated in an origami-inspired framework, enables precise detection under extreme dynamic loading.
The research team developed a novel vascularised tumour model using a non-surgical injectable hydrogel system, providing a powerful new platform for researching cancer and testing immune cell therapies. The breakthrough model effectively supports the spontaneous formation of solid tumours with functional host-derived vasculature in mice.
Researchers discovered a 'sticky' molecule, P-selectin, that can cause blood clots and organ failure during COVID-19. A new mRNA therapy that drives P-selectin expression provides broad protection against coronavirus infection.
Archaeologists uncover vast planned settlement Semiyarka, dating back to 1600 BC, which challenges current understanding of steppe societies and reveals complex bronze production systems. The site provides insight into a period of history when nomadic communities transitioned into permanent settlements.
A study published in JAMA Network Open reveals significant racial disparities in cesarean births, with Black individuals facing a higher risk of the procedure despite efforts to decrease overall rates. The research highlights the need for upstream interventions and education to address structural racism in maternal health care.
A team of scientists has uncovered evidence of ancient wildfires during the Early Triassic epoch, about 250 million years ago. The findings suggest that wildfires played a significant role in shaping ecosystems during this time period, contrary to previous assumptions based on a lack of charcoal in the geologic record.
The European Centre for Medium-Range Weather Forecasts (ECMWF) and several National Meteorological Services across Europe have been honored with the 2025 HPCwire Readers’ and Editors’ Choice Award for
The study definitively resolves the controversy by capturing complete two-dimensional snapshots of electron spin and orbital shape on the Au(111) Shockley surface state. The experiment unambiguously confirms the Rashba effect, establishing a robust reference dataset for spin-resolved photoemission.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
The Shika Sonic device, developed to deter wild animals like bears and deer, was installed near a school in Nanto City, Toyama Prefecture. Since its installation, there have been zero bear sightings in the surrounding area. The city is now considering expanding the use of the device to tourist areas based on promising results.
Dr. Leanne Redman joins the Charles Perkins Centre to lead research on obesity, diet, and exercise, building on her extensive experience in women's health issues and translational research. With over 300 publications and numerous awards, she will expand the centre's impact on global health.
Researchers identified eight different long COVID trajectories, depending on severity and duration of symptoms, in a study of over 3,500 adult participants. The study found that 10.3% of patients had long COVID symptoms three months after infection, with 81% continuing to experience persistent or intermittent symptoms a year later.
Researchers found that CRISPR-Cas9 gene editing persists longer and produces more predictable results in non-dividing neurons. They also discovered new DNA repair genes that can be used to control gene editing outcomes, which could lead to safer and more effective therapies for genetic diseases.
Researchers have successfully engineered functional brain-like tissue without animal-derived materials, opening doors to more controlled and humane neurological drug testing. The new material functions as a scaffold for donor brain cells and can be used to model traumatic brain injuries or neurological diseases like Alzheimer's.
Researchers developed a comprehensive theory to interpret how water molecules interact with contrast agents in MRI scans, offering more accurate predictions and explanations of NMR relaxation. This advancement paves the way for new insights into medical imaging and materials science.
Researchers at Cleveland Clinic and IBM developed a hybrid quantum-classical model to simulate molecular interactions. The study accurately simulated two supramolecular systems, water dimer and methane dimer, for the first time using quantum computers.
Researchers at FAMU-FSU College of Engineering have developed a design that uses multiple strands of superconducting tape to create a cable, minimizing the chance of failure from defective spots within a wire. This technology helps solve engineering and manufacturing challenges for manufacturers and could lead to more efficient and les...
A recent study by researchers from the University of Rochester, University of Illinois Urbana–Champaign, and University of Virginia found that publicly displayed community notes can effectively curb misinformation on social media platforms. The study analyzed 264,600 posts on X that received at least one community note and found that p...
Dr. Muhammad Aziz presents his cutting-edge research on chemical looping-based hydrogen production, generating high-purity hydrogen and capturing CO2 while recovering usable heat or power. His work spans from microscopic analysis to system-level integration across energy and heavy industries.
A University of Delaware study uses robotic testing to gauge perception-based movement in stroke survivors, revealing hidden sensory losses. The researchers hope their findings will encourage clinicians to integrate precision testing into assessments, leading to a personalized medicine approach to treatment.
The latest edition of Geysers: What They Are and How They Work offers fresh insights into the shifting activity and personalities of Yellowstone's iconic geysers. Readers will discover why some erupt with clockwork regularity while others slumber for decades before roaring back to life.
Researchers found that Kīlauea's magma system started behaving anomalously about a year before the 2018 eruption, suggesting a blockage formed between the volcano's summit magma reservoirs. Continuous monitoring data accumulated, gaining insights into Kīlauea's inner workings and its long-term behavior.
A recent study published in Annals of Internal Medicine found that over 69,000 US deaths were caused by extreme temperature exposure between 1999 and 2024. The majority of these deaths were heat-related, but cold-related deaths are also expected to rise as climate change intensifies.
The American College of Physicians (ACP) has issued new influenza vaccine practice points that recommend standard-dose trivalent or quadrivalent vaccines for healthy adults aged 18-64, and high-dose trivalent or quadrivalent vaccines for those 65 years old. The guidelines aim to prevent seasonal epidemics caused by highly infectious fl...
A new study by University of Notre Dame researcher Helge-Johannes Marahrens shows that analyzing social media posts can help experts predict when people will move during crises. Sentiment was found to be a more reliable signal for predicting forced displacement than emotion.
Researchers create a new material that dramatically boosts uranium extraction efficiency, addressing one of the key challenges in sustainable nuclear energy. The study introduces a special type of covalent organic framework (COF) that shows record-high efficiency and selectivity in isolating uranium from seawater.
Engineers at UC San Diego developed a wearable system that enables people to control machines using everyday gestures even in highly dynamic environments. The system combines stretchable electronics and AI to overcome the limitation of gesture signals falling apart under excessive motion noise.
The study highlights how emerging pollutants such as pharmaceuticals, microplastics, and industrial chemicals interfere with biological phosphorus removal processes in wastewater treatment plants. The review emphasizes the need for updated strategies and experimental designs to address these new contaminants.
A study published in npj Ocean Sustainability reveals that traditional Hawaiian fishponds (loko iʻa) effectively shield fish populations from the negative impacts of climate change. The research found that loko iʻa fish populations were more resilient to rising water temperatures than those in surrounding estuaries.
Researchers found that rats contributed significantly to Rapa Nui's deforestation by consuming palm nuts, preventing trees from regrowing. The islanders cleared land for agriculture and used slash-and-burn practices, but the slow-growing palm trees made them vulnerable to rat predation.
Researchers developed a new type of porous gel that solves the problem of dense gels hindering the passage of microbes and immune cells. The new material supported better growth and organisation of bone marrow cells and helped the formation of structures similar to blood vessels, allowing fluids and particles to flow more efficiently.
A new study by Boston University School of Public Health researchers found that child firearm injuries rise as soon as the school day ends, with a peak risk in the first 15 minutes after dismissal. Community-level interventions providing safe spaces for youth are crucial to prevent such violence.
Research reveals that medications can reshape the trillions of microbes in the gut by competing for nutrients, leading to predictable changes in the microbiome. The study provides a framework for predicting how a person's microbial community might change with a given drug, potentially helping scientists find ways to prevent side effects.
The University of Nebraska-Lincoln has received a $2.5 million grant from the Department of Energy to investigate ferroelectric oxides and control oxide and van der Waals materials in ways previously thought impossible. The research aims to create new, energy-efficient electronic devices and platforms for smartphones.
A new study reveals fresh chemical evidence of life in rocks over 3.3 billion years old, with molecular traces showing oxygen-producing photosynthesis emerged nearly a billion years earlier than thought. The approach uses machine learning to recognize subtle molecular fingerprints left behind by living organisms.
A team of scientists has discovered chemical evidence of ancient life in 3.3 billion-year-old rocks, doubling the window of time for detecting organic molecules that reveal information about original organisms. The study also found molecular signs of photosynthesis dating back over 800 million years earlier than previously documented.
Muscle stem cells secrete c1qtnf3, which redirects macrophages from immune to regenerative functions, promoting tadpole tail regeneration. This discovery offers insights into the regenerative capabilities of certain animals and paves the way for further research into potential applications in mammals.
Researchers developed a fully coupled optical, electrical and thermal-fluid model for a parabolic-trough CPV-T collector with spectral-splitting liquid filters. The design achieved high-performance solar thermal energy generation, reaching maximum thermal efficiency of 45% and electrical efficiency of 15%.
A landmark international study finds that hospitals with better nurse staffing and work environments are significantly associated with less physician burnout and job dissatisfaction. Investing in nurses improves both nurse and physician wellbeing, while strengthening patient care.
A recent study by Ocean Conservancy reveals that consuming as little as three sugar cubes' worth of plastics can be fatal to seabirds, while less than one-sixth of a soccer ball's worth can kill sea turtles. Marine mammals are also vulnerable, with nearly half dying from ingesting plastics, often of varying types.
A 12,000-year-old clay figurine from Nahal Ein Gev II in northern Israel depicts a woman and goose, revealing human-animal interaction and symbolic expression. The piece showcases naturalism, light manipulation, and artistic innovations predating the Neolithic era.
This study develops an interpretable machine learning model that integrates proteomics and clinical data to predict 5-year survival in breast cancer. The model uses SHAP and KAN to identify key predictive factors, achieving high accuracy and robust predictive capability.
A new study reveals AI can corrupt public opinion surveys at scale, passing quality checks and flipping predicted outcomes with fake responses. The findings have significant implications for scientific research and policy-making, highlighting the need for transparency and verification of human participation.
The book highlights how AI tools enhance crop monitoring, pest control, and water conservation through data-driven insights and predictive modeling. It offers practical guidance for researchers, agricultural professionals, and technologists on applying AI responsibly in rural and emerging economies.
A new study found that medieval European societies supported plant diversity around Lake Constance, driven by agricultural practices and land management. Researchers integrated fossil pollen data with historical records to reconstruct the region's 4000-year history of biodiversity change.
The book explores how CEH can enhance yield, quality, and resource efficiency through technological innovation. It also highlights the role of biotechnology in ensuring global food security.
A collaboration between physics, neuroscience groups develops a unified model of memory and perception. The study suggests that distinct perceptual biases can be explained by a single biologically grounded mechanism, Hebbian learning.
This book explores the impact of decentralized networks on industries like healthcare and supply chains, highlighting the benefits of blockchain technology. It also delves into the synergy between blockchain and emerging technologies like AI and IoT.
This book provides an in-depth overview of 120 wild vegetable species from India's Western Ghats biodiversity region, covering their morphology, phytochemistry, traditional uses, and nutritional composition. It connects indigenous knowledge with modern plant science to promote the sustainable use of underutilized edible plants.
The iMetaMed initiative aims to integrate diverse perspectives in medicine by dissolving disciplinary boundaries. It leverages AI, big data, and open science to advance precision diagnostics, drug discovery, and personalized treatment protocols.
A study by UCLA's Brian Wood and University of Michigan's John Mitani found a link between lethal aggression, territorial expansion, and improved reproductive success in wild chimpanzees. The Ngogo group's territory grew after coordinated attacks, leading to increased fertility and survival rates among females.
Researchers developed a novel tool, the Preterm Birth Actionable Risk Index (PTB-ARIx), to assess risk for premature births. The index identifies 18 specific risk factors during pregnancy that can be treated with evidence-based interventions.
A new study by University of Exeter's Elections Centre finds that small changes in voter turnout can significantly impact election outcomes due to the UK's multiparty system. The research reveals a fragmented electorate with diverse preferences, leading to increased instability and competitiveness in constituencies.
Rockefeller researchers found a molecular switch in breast cancer cells that reprograms gene expression towards tumor growth and stress resistance. This switch is mediated by the MED1 subunit of RNA polymerase II and can be activated under stressful conditions, leading to faster-growing and more stress-resistant tumors.
Researchers at Institut Pasteur found that aminoglycosides use sugar transporters to enter bacteria, increasing their effectiveness and potentially reducing the need for high doses. By doubling the number of transporters, they improved antibiotics' penetration rate and efficacy in even the most resistant E. coli strains.
The statement provides guidance as countries debate closing ambition gap at COP30 and small island states call for honoring 1.5°C goal. Research shows that limiting overshoot and returning below 1.5°C is still possible with quick emissions fall and clean-energy deployment acceleration.
Clinical trial participants are calling for more inclusive and patient-centered cancer research, highlighting the need for transparent designs and improved communication. The authors propose various improvements to trial design and delivery, including expanding eligibility criteria and involving patient advocates in trial design.
Research suggests that health apps, wearables, and interactive programs can improve physical activity, diet, and weight outcomes for children and teens. Mobile apps had the greatest impact on diet and weight outcomes, while wearables were most effective for reducing sedentary time.
Researchers at the University of Arizona Comprehensive Cancer Center are investigating novel immune-based approaches to prevent keratinocytic skin cancers. They aim to identify early immune signals that can activate the body's own immune defenses to prevent cancer before it starts.
A new electronic medical records-based tool predicts which patients are most at risk of losing a transplanted kidney graft, allowing for timely interventions. The study achieved high predictive accuracy and can be implemented to streamline care of recipients.
Researchers proposed ACAL system for fabricating micro ring-shaped metasurface unit cells on highly curved substrates, demonstrating extended depth of focus and robustness against defocus. The method improved minimum annular feature size by over 10 times compared to conventional methods.
Researchers Sang-Ho Kim, An-Ping Li, Bronson Messer and Zac Ward recognized for their distinguished achievements in physics. They were cited by the APS Division of Physics of Beams, Topical Group on Instrument and Measurement Science, Forum on Outreach and Engaging the Public, and Forum on Physics and Society.
A synthetic microbial consortium, combining Shewanella oneidensis MR-1 and Pseudomonas aeruginosa LXZ1, completely reduces soluble uranium to insoluble U(IV) within 48 hours. The cooperative system accelerates extracellular electron transfer through pyocyanin-mediated interaction and extracellular DNA conductive networks.
A new study by VCU researchers found that almost all participants perceived a suspect as being in custody after only a short period of time, even though they had not been formally arrested. The research used virtual reality headsets to examine how people perceive police custody from 'inside' the interrogation room.
Researchers have discovered a new gene, ALOX15, that protects against sepsis-induced lung injury in mouse models. The findings suggest that mild lung thrombosis may actually reduce the severity of lung damage from sepsis, offering a potential novel therapeutic strategy.
A study by Fisabio found that children who owned 'other animals' had a protective effect against emotional problems, while cat ownership at ages 4-5 showed a mild association. The study suggests that less demanding pets may help create stable relationships and enhance psychological well-being.
A team of researchers from the University of Arkansas System Division of Agriculture identified the base, optimal and maximum temperature ranges for eight commonly grown cover crop species. The study's findings provide significant guidance for developing accurate plant growth and biomass prediction models.
A novel study aims to uncover the connections between Fanconi Anemia and nervous system development, as well as nervous system decline. Researchers use C. elegans worms with FA gene mutations to track neural cell damage and behavior changes.
The new SOFA-2 system updates the global reference for assessing organ dysfunction in intensive care, reflecting advances in diagnostics and life support. With over 3.3 million ICU admissions analyzed, SOFA-2 provides a more accurate representation of critical care management.
A new urine test can detect SORD deficiency, a common cause of inherited nerve disease, earlier and more cheaply than genetic tests. The test has brought understanding and access to care for affected families, particularly in the Old Order Amish community.
John Lyons, a physical scientist at NRL's Materials Science and Technology Division, has been selected as an APS Fellow for his work on wide-band-gap semiconductors. His research focuses on understanding doping and defects in materials like gallium oxide and gallium nitride, key to next-generation radar and high-power electronic systems.
Researchers have developed a new machine learning-based algorithm called Coralysis to integrate complex single-cell data, overcoming challenges in identifying and grouping cell types. The method can detect changing cellular states and estimate confidence levels, streamlining the analysis process.
A clinical trial at UCI Health has tested a new CAR T-cell therapy for lupus patients. The treatment showed significant reversal of symptoms in the first trial participant, offering hope for future treatments.
Current PRRSV vaccines offer protection through a T cell response, rather than antibody production. Vaccination induces an immune response that identifies and attacks conserved parts of the virus.
A new study using CALIOP lidar data found nearly 10% of atmospheric profiles feature ambiguous transition zones between clouds and aerosols. The high frequency of these zones poses a challenge to current climate models, highlighting the need for more sophisticated representations of atmospheric particles.
Researchers have identified a protein complex that drives T cell exhaustion in tumors and show that disrupting it can revive exhausted anti-tumor CTLs. The study's findings offer new hope for improving the efficacy of cancer immunotherapy.
A study published in Nature Communications found that while some municipal wastewater samples select for antibiotic-resistant E. coli, most instead suppress their growth, suggesting wastewater treatment plants may not be breeding grounds for resistance as commonly thought.
The study by researchers at Oregon State University and Utrecht University found that children of parents with high levels of acceptance and low negativity tend to struggle less with their own parenting, while those who experienced little acceptance and a lot of negativity as children are more likely to become parents with similar diff...
Security researchers have developed a defense mechanism that protects against cryptanalytic parameter extraction attacks on AI systems. By making neurons in the same layer similar to each other, the defense creates a barrier of similarity that makes it difficult for attacks to proceed.
Research found that investing in staff training led to a 4% increase in new residents, while improved pay conditions resulted in a 3.1% increase. However, beyond a certain threshold of collective skills and experience, further improvements require additional interventions.
A recent study has found that certain painkillers can increase hepcidin production in liver cancer cells, leading to iron deficiency and anemia. The researchers discovered that diclofenac and paracetamol alter the activity of signaling pathways within cancer cells.
The team discovered a flat, spherical gas and dust structure resembling a diamond ring, formed by a massive star's radiation and winds. The 'Diamond Ring' is around 20 light years in diameter and shines strongly in infrared light.
A new study found that the brain encodes molecular features of odors early on to support odor discrimination, while representing subjective attributes like pleasantness later. This distinction can be used to assess olfactory disorders or enhance function.
A recent study from the University of Kansas found that a 2023 police raid on a small-town newspaper in Kansas sparked
A new species of wolf snake, Lycodon irwini, has been discovered in the Great Nicobar Islands and named in honor of Steve Irwin. The snakes are glossy black, non-venomous, and likely feed on reptiles and small mammals.
A new recycling process recovers nearly all valuable materials from used batteries with high purity, requiring less energy, chemicals, and costs compared to existing methods. The two-step flash Joule heating method separates lithium and transition metals quickly and cleanly.
Biosurfactants, such as rhamnolipids and sophorolipids, have been found to be highly effective and biodegradable alternatives to synthetic surfactants in shampoo formulations. They offer improved environmental compatibility and are suitable for sensitive skin, with properties that surpass those of traditional surfactants.
Researchers found that immune cells in the gut follow an atypical pathway to produce antibodies providing long-term protection against viruses. The study could help guide the development of better vaccines for respiratory viruses like influenza and SARS-CoV-2.
Researchers at the University of Missouri discovered that adding oil-based dressings or sauces to kale increases its carotenoid absorption. Cooking with these dressings is equally effective as mixing them in after cooking. The study suggests novel dressings could further boost nutrient absorption from other vegetables.
Despite national policy, palliative care is often not equally accessible to all, with most people dying in hospitals or nursing homes rather than at home. The researchers emphasize the need for systematic implementation and integration of person-centred palliative care across different care settings.
A team of researchers has developed an improved version of the Zebiak-Cane model by fine-tuning key atmospheric parameters, resulting in more realistic ENSO simulations. The study demonstrates that adjusting heating efficiency, drag coefficient, and frictional coefficient can mitigate biases and improve the model's realism.
A study conducted in a Japanese ICU found that healthcare workers experience reduced satisfaction and concentration due to poor lighting and excessive noise. The findings suggest that designing ICUs with improved natural light and mitigating noise can enhance worker satisfaction, productivity, and quality of patient care.
A Rutgers Health-led study found that Medicaid expansion increased PrEP prescriptions overall, but racial disparities in access persisted. White Americans received the most PrEP prescriptions (94%), while Black and Hispanic communities were underrepresented, with 13% and 24% respectively.
Dr. Sedrak receives King Hussein Cancer Research Award for innovative work on accelerated aging in cancer survivors, with a focus on developing new strategies to prevent or reverse age-related effects. His research aims to improve health span and quality of life for cancer patients, holding promise for other age-related diseases.
Scientists propose and experimentally realize optical skyrmions in the spatiotemporal domain using transverse orbital angular momentum and vectorial shaping of pulsed light. The structures exhibit fascinating evolution during propagation, including the Gouy phase shift and changing beam size.
Researchers propose a novel approach to ensure uniform backfilling throughout borehole depth, addressing immediate safety concerns and long-term sustainability. The circulating mixing method improves process parameters and quality control through advanced numerical simulations.
A UVA-led team is part of a national project funded by ARPA-H to create an intelligent indoor air system that detects pathogens and responds with interventions. The BRAVE system aims to revolutionize public health by anticipating and mitigating outbreaks before they spread.
A new type of 3D-printable material made from polyethylene glycol has been developed by a University of Virginia research team. This breakthrough material is biologically friendly and can be stretched, making it suitable for use in larger structures or those requiring flexibility.
Nanoemulsions in cosmetics provide efficient carriers for active ingredients, maintaining product efficacy and bioavailability. Their stability ensures sustained release of actives, reducing the need for frequent application.
A team of researchers has successfully developed niobium disulfide metallic nanotubes with predictable properties, a long-sought goal in advanced materials science. The breakthrough was made possible by adding table salt to the growth process, which helped create stable shells and revealed two-layer tubes.
Researchers will study neural mechanisms of visual perceptual learning (VPL) to generalize across the visual field, improving vision rehabilitation and AI systems. The project aims to develop a unified model of visual processing, VPL, and attention.
Research using brain-computer interface reveals tirzepatide's temporary suppression of brain activity involved in 'food noise' in a patient with severe obesity, calling for further investigation. The medication, originally developed to manage Type 2 diabetes, may have potential in treating impulse control disorders like binge eating di...
A 20-year study of 11,000 adults in Bangladesh found that reducing arsenic levels in drinking water was associated with lower mortality rates from heart disease, cancer, and other chronic illnesses. The study provides the first long-term, individual-level evidence that reducing arsenic exposure may lower mortality even among people exp...
Researchers at Technion-Israel Institute of Technology identify a unique mechanism in the aging of the immune system and propose a framework for improving its function in older individuals. Controlled iron supplementation has been shown to improve T-cell activation and enhance the immune response in elderly mice.
A parasitic ant queen tricks ant workers into killing their queen mother by spraying a foul-smelling chemical, causing her daughters to turn against her. The parasitic queen then usurps the throne and is served by the workers.
A US cohort study from 2012-2021 found persistent disparities in cesarean births by race and ethnicity, with non-Hispanic Black individuals facing increased risks. The study highlights the need for quality improvement efforts to address structural racism and reduce unnecessary cesarean births.
Researchers in Japan have developed a supramolecular polymer system that can adaptively transform into different dimensional states depending on the intensity of light applied, revealing mechanisms behind these dynamic transformations using high-speed atomic force microscopy.
Legged robots face difficulties in hardware design and control due to impact force and kinematic complexity. Single-leg robots offer a simplified alternative for hopping and biomimetic motion, with various structures, modeling, and control strategies being explored.
A new online calculator uses percentiles to help younger adults forecast their risk of a heart event over the next 30 years. The tool calculates a person's 30-year risk of developing heart disease using common health measures, such as blood pressure and cholesterol.
A 20-year study found that reducing arsenic exposure lowered mortality rates from heart disease, cancer, and other chronic illnesses. Participants with lower arsenic levels had significantly lower mortality risks compared to those with continued high exposure.
Researchers have developed an innovative antibody-based enzyme switch called 'Switchbody', which is activated upon antigen binding. The switch's mechanism relies on a 'trap-and-release' process, offering new opportunities in diagnostics and therapeutics.
The new facility can test thermal performance of heat exchangers and cooling equipment up to five megawatts, supporting the growing $30 billion data center cooling industry. SwRI offers customized testing services, including coolant distribution units and secondary side pumps, and replicates real-world conditions.
A recent study published by the American Psychological Association found that about a quarter of U.S. service members and veterans who start psychotherapy for post-traumatic stress disorder (PTSD) quit before finishing treatment. The study analyzed 181 studies covering over 124,000 military participants and discovered significant diffe...
The Chinese Society of Hepatology outlines a structured framework for monitoring, diagnosing, preventing, and managing drug-induced liver injury in patients with hepatocellular carcinoma. Key risk factors include underlying liver disease, genetic predisposition, and drug-specific factors.
A new Yale study found that only 24% of medicines tested in clinical trials received market authorization, highlighting a significant 'test it but don't sell it' problem. The study highlights the need for collective effort from pharma companies, countries, and other stakeholders to improve post-trial access to life-saving medicines.
Approximately 1 in 30 clinical trials were disrupted due to grant funding terminations, disproportionately affecting infectious disease and prevention studies. The study emphasizes the need for sustainable financial support to ensure trial operations and participant safety.
A Spanish study involving over 4,000 participants found that 4 out of 10 perceive menstruation as a stigmatised topic. The research highlights the persistence of stigma and its consequences on self-esteem and emotional well-being.
Researchers have created a detailed map of a bacteriophage, a virus that targets and kills harmful bacteria. The study's findings hold promise for developing new therapies to combat antibiotic resistance.
The upgraded engine features a state-of-the-art turbocharger, increasing peak torque from 1,494 to 1,760-foot pounds and peak power from 370 to 440 horsepower. The engine's peak efficiency has also improved to 44.0%, class-leading for a spark-ignited engine.
Most San Diego County beaches grew in width last year during the post-El Niño recovery phase. California's average beach width has remained stable across nearly four decades despite notable examples of beach erosion. Beach nourishment projects also contributed to recent increases in beach width.
A new study finds that reducing arsenic levels in drinking water can decrease death rates from chronic diseases such as heart disease and cancer. Over a 20-year period, efforts to lower arsenic levels resulted in a 70% decrease in chemical levels, halving arsenic levels in urine among study participants.
A new study found that nearly 1 in 5 citations generated by GPT-4o were entirely fabricated, while over two-thirds contained errors, indicating a major reliability issue. Researchers and journals must implement stronger safeguards to validate accuracy and authenticity.
A new study examines the role of social approval in intercultural relationships, finding that supportive friends are a powerful protective factor. The research highlights the unique challenges faced by these couples and emphasizes the importance of building strong social networks to understand and respect their relationship.
Researchers at The University of Osaka have developed a novel Balloon-Assisted Bronchoscope Delivery (BDBD) technique, enabling safe access to small, early-stage lung cancers hidden in the peripheral lung fields. This innovation promises to revolutionize both early diagnosis and minimally invasive treatment.
A study from Gladstone Institutes finds that dysfunctional mitochondria can initiate Parkinson's disease. The researchers used a unique mouse model to demonstrate the link between mitochondrial dysfunction and energy breakdown in cells, shedding light on potential new treatments.
The Ontario Hereditary Cancer Research Network has created a comprehensive provincial database to support research on cancers passed down through genetics. Ontarians at risk of hereditary cancers can now register for access to clinical trials, advocacy groups, and other resources.
Researchers identified distinct epigenetic signatures in cord blood linked to increased schizophrenia and other neurodevelopmental conditions. Newborns with higher genetic susceptibility showed differences in DNA methylation patterns, especially in immune-related regions.
The world's online population grew to 6 billion, while 2.2 billion remain offline, highlighting the importance of digital infrastructure, affordable services, and skills training to achieve universal connectivity. Deep digital divides persist, with uneven coverage, affordability, and skill levels across high- and low-income countries.
Researchers at UC San Diego School of Medicine have identified a promising new therapy for triple-negative breast cancer (TNBC), employing an antibody-drug conjugate to deliver chemotherapy directly into cancer cells. Targeting tumor-initiating cells through FZD7 may offer a path forward for patients with aggressive TNBC that fails to ...
A recent study at UC Davis has shown that feeding cows red seaweed can dramatically cut the amount of methane produced, with a 60% reduction in emissions. The research identified specific microbes in the cow's gut that help reduce methane production, opening the door to engineering these microbes for a long-term solution.
Researchers discover a new parasitic strategy where an invading ant queen uses a chemical spray to manipulate host workers into killing their own mother. The study details two species of parasitic ants that use formic acid as a chemical camouflage to get past the colony's defenses.
Researchers from Zhejiang University analyzed crucial factors influencing crystallization in blade-coated perovskite films. The study identifies interconnected factors controlling crystal nucleation, grain evolution, and defect distribution.
A team of New York University researchers has identified the orbitofrontal cortex as an 'inference engine' that allows animals to update their understanding of their surroundings based on changing circumstances. The study found that trained rats waited longer for water rewards in low states and less time in reward-rich states, indicati...
A study found that lowered arsenic exposure was associated with a decrease in mortality rates from chronic diseases among populations exposed to contaminated drinking water. The findings support the importance of reducing arsenic levels in drinking water for public health benefits.
Researchers have shown that disabling the NRF2 gene with CRISPR technology can restore drug sensitivity and slow tumor growth in lung cancer. The approach, which targets a master switch for resistance, has potential across multiple tumor types.
A new study by Duke-NUS reveals that almost all community-dwelling older adults with advanced dementia experience at least one potentially burdensome intervention in their last year of life. The study highlights the need for new strategies to support families and reduce unnecessary interventions at the end of life.
The American Heart Association is scaling up its efforts to improve diagnosis and treatment of hypertrophic cardiomyopathy (HCM), the most common inherited heart disease. With new support from Cytokinetics, the program will standardize care for HCM patients, aiming to improve patient outcomes and reduce risks associated with the disease.
A Boston University study finds nearly 14% of the US population lives within a mile of fossil fuel infrastructure, posing potential health risks. The research highlights inequities in exposure, with predominantly non-white groups and urbanites disproportionately affected.
World COPD Day on November 19 highlights the significance of correctly diagnosing chronic obstructive pulmonary disease (COPD) earlier. Up to 70% of adults with COPD remain undiagnosed, leading to poorer quality of life and health outcomes. Active case finding through spirometry can improve diagnosis and treatment.
Scientists have built a highly realistic brain simulation of a mouse cortex using the powerful Supercomputer Fugaku, allowing them to simulate diseases like Alzheimer's and epilepsy in detail. This breakthrough enables researchers to test hypotheses virtually and potentially find answers for brain disorders before symptoms appear.
A study of over 27,000 collegiate athlete sleep records found that early morning team practices lead to reduced sleep time and lower sleep efficiency scores. Male athletes averaged 30 minutes less sleep, while female athletes averaged 20 minutes less, with both experiencing longer wake-up times and reduced sleep quality.
Researchers found that providing information on the benefits of public goods increases support for higher taxation, with effects observed across income levels and political stances. The study suggests that investment in public goods can act as a 'political foundation' to enhance citizens' support for government and enable redistribution.
A new study published in the Hypertension Journal found that chronic pain in adults may increase their risk of developing high blood pressure, with depression playing a significant role. The study analyzed data from over 200,000 adults and found that widespread pain was associated with a higher risk of high blood pressure.
Weill Cornell Medicine researchers have discovered a molecular signal that tumors exploit to exhaust T cells meant to destroy them. By silencing this signal, the body's immunity can be revived and cancer-fighting immune cells restored.
A study by neuroscientists found that babies born blind retain the ability to recognize faces and objects, but not small details like contours, in their brains. The research suggests that early vision loss may not hinder brain development as much as previously thought, paving the way for new visual therapies.
Researchers developed a standardized language for describing cannabis and hemp aromas, which can aid in quality assessment beyond THC potency. The study found that hemp and cannabis exhibit overlapping sensory profiles, with distinct aroma characteristics emerging from each.
Marine carbon dioxide removal technologies have the potential to play a role in mitigating global warming, but verifying their effectiveness and ensuring they don't harm the ocean is crucial. The European Marine Board report highlights the need for measures to ensure these technologies are used responsibly.
A new study on artificial reproductive technologies found that mice conceived with IVF have slightly increased rates of DNA errors compared to those conceived naturally. The researchers discovered a 30% increase in new single-nucleotide variants, which are unlikely to be harmful.
A new study found that Critically Endangered African penguins are more likely to forage in areas with commercial fishing vessels during years of low fish abundance, increasing competition and pressure on the species. The research introduces a novel metric called
A case study in CMAJ describes successful ovarian tissue preservation in a young woman with Hodgkin lymphoma, highlighting the need for improved access to fertility preservation services. The 'hub-and-spoke' model presented offers a potential solution to overcome geographical barriers and improve patient outcomes.
A qualitative study found that physician responses to patient expectations contribute to pay gaps among Canadian physicians, particularly women, racialized, and immigrant physicians. Researchers suggest adjusting compensation models for extra time required for certain care types and examining fee schedules for underpaid services.
Researchers used brain stimulation to synchronize communication between visual regions and enhance motion perception in stroke patients. The approach showed significant improvements in visual fields and real-world performance, suggesting a faster, more accessible therapy for hemianopia recovery.
Older workers, particularly Black and Latino individuals, face increased risk of work disability due to extreme heat exposure. Researchers highlight the need for comprehensive workplace safeguards and access to healthcare.