The new statistical method adapts to data structure, resisting outliers and providing greater stability on non-Euclidean spaces. This improves the reliability of analysis in areas like medical imaging, computer vision, and machine learning.
Therapeutic education is becoming a dominant force in UK primary schools, prioritizing emotional literacy and empathy over traditional moral values. While this approach can build empathy and community, it also risks individualising children's moral development and placing responsibility on the child.
Researchers used human-induced pluripotent stem cell-derived kidney organoids to model nephronophthisis, revealing the Hippo signaling pathway's role in fibrosis. Inhibiting this pathway with drugs like verteporfin shows promise as a treatment option.
Melanie Wells' tenure as ACMG CEO concluded on November 21, 2025, with significant operational transformation and financial stabilization. She led the organization through a period of remarkable progress and transformation.
A European research team has achieved electrical control of spin currents in graphene through ferroelectric switching, offering a novel pathway toward energy-efficient spintronic devices. This discovery enables the fabrication of next-generation spin-based logic and memory systems without relying on external magnetic fields.
A comprehensive review of over 25 years of research on non-specific vaccine effects reveals no evidence to support the claim that vaccines protect against diseases other than the ones they are designed to prevent. The study, which analyzed 13 randomized trials, shows that prominent researchers have systematically over-interpreted the f...
A new study reveals that ocean acidification is accelerating at a rate outpacing atmospheric CO2 levels, with the Northeastern Pacific Ocean experiencing rapid acidification. The research analyzed coral skeletons from the past century, showing that CO2 has been accumulating in North American waters faster than in the atmosphere.
Scientists have achieved control over the atomic structure of perovskites, creating a finely tuned energy sandwich that could transform how solar cells, LEDs, and lasers are made. The new method enables precise control over the thickness of films and interaction between layers, paving the way for scalable and high-performance devices.
A new review provides simplified criteria for defining gout remission and proposes integrated management strategies for sustained disease control. The authors highlight the importance of individualized urate-lowering therapy and proactive flare prevention, using imaging to show patients visual proof of crystal dissolution.
Researchers Andrew Gewirtz and Lanying Du from the Institute for Biomedical Sciences at Georgia State University have been recognized as Highly Cited Researchers in 2025. They are among the top 1% of globally impactful researchers, with highly cited papers in multiple fields.
A study of an Early Triassic-age fossil site in the Arctic found complex and diverse oceanic ecosystems, with many marine tetrapod lineages diversifying soon after the end-Permian mass extinction event. The findings suggest that vertebrate evolution paralleled the rapid resurgence of invertebrate life in the Early Triassic.
Zalunfiban, a next-generation GPIIb/IIIa inhibitor, met its efficacy and safety endpoints in treating STEMI patients. The drug was developed with support from Harrington Discovery Institute at University Hospitals, which provided advanced drug and business development support.
Lymphomas develop resistance to targeted therapies through various mechanisms, including loss of target antigens, reactivation of growth pathways, and changes in tumor microenvironment. Researchers explore new treatment approaches, such as dual-target therapies and biomarker-guided therapy, to overcome these challenges.
Researchers at Institute of Science Tokyo found that European eels have restored aquaporin proteins with broad solute permeability through a recent gene duplication event. The study revealed that the genes Aqp10.2b2 and b3 acquired functional diversification, enabling them to transport urea and boric acid similar to Aqp10.1.
Researchers have discovered that diseased oak trees emit distinct odours that attract the beetle Agrilus biguttatus, a key contributor to the decline. The study sheds light on the complex interplay between trees, microbes, and insects in oak health crises.
A recent study published in Global Change Biology found that functional diversity helps keep forest growth stable during prolonged periods of drought. Trees with different water-use strategies show stronger growth in drought years than those with opposite strategies.
A new study from Duke-NUS Medical School reveals how AI can revolutionize medical education by personalizing learning experiences, simulating clinical scenarios, and supporting research. Stronger collaboration across schools, hospitals, and regulators is needed to make AI safe, responsible, and effective.
Efficiency rankings may misrepresent performance due to sudden disruptions or gradual improvements, according to a new study. The Time Envelopment Analysis (TEA) method developed by researchers combines three tools to track performance over time, showing improved accuracy compared to existing methods.
A study by Boston University researchers has found that a prison superintendent's recommendation and an applicant's inability to perform activities of daily living (ADLs) are the only factors with a statistically significant correlation to medical parole being granted. This suggests that the superintendent's recommendation plays a cruc...
Researchers are developing Refractory High-Entropy Alloys with improved strength and ductility through computation-led design and sophisticated microstructures. These advancements aim to overcome the traditional trade-off between mechanical properties.
A new study in a US prison suggests that incarcerated individuals prioritize accessibility, support, and humane treatment from staff. The study's findings highlight the potential implications of negative emotions such as frustration and feeling uncared for on relationships between staff and inmates.
The American Association for Dental, Oral, and Craniofacial Research (AADOCR) has announced the sixth cohort of its Mind the Future program, a mentoring network designed to support early-career researchers. The program aims to enhance career development in dental, oral, and craniofacial health research.
University Hospitals Cleveland Medical Center has received a top hospital safety grade of 'A' from the Leapfrog Group, demonstrating its commitment to zero harm and quality care. The hospital's Zero Harm initiatives have reduced infections, improved outcomes, and enhanced patient safety.
A new genomic study found that dogs traveled with humans as they migrated across Eurasia, forming part of cultural and biological exchanges. The study analyzed ancient dog genomes alongside human and modern dog genomes, revealing coincidences between dog movement and human migration patterns.
Researchers have discovered that certain seawater ions can be intentionally utilized to enhance electrochemical performance, rather than hindering it. This involves carefully designing catalysts and electrolytes to mitigate the negative effects of these ions while maximizing their benefits.
Research by the University of Stirling found that beaver-created wetlands have a significant impact on pollinator populations, with a 29% increase in hoverfly species and 119% more individuals. This study suggests that beavers can play a crucial role in boosting biodiversity and reversing declining pollinator numbers.
Researchers conclude that the hypothesis of a causal relationship between the gut microbiome and autism is unsupported by science. Key findings include inadequate sample sizes and flawed statistical methods in studies attempting to establish this link. The authors argue for a more rigorous approach to studying this topic.
A new study reveals that domestic dogs developed their distinctive forms thousands of years before modern breeding practices. Early Holocene dogs exhibited roughly half the morphological range seen in modern dogs, with notable variation emerging millennia before modern breeds.
Researchers at ETH Zurich developed microrobots that can navigate blood vessels with precision, delivering drugs directly to the target location. The robots use magnetic nanoparticles and advanced navigation systems to avoid obstacles and reach their destination.
A University of Massachusetts Amherst study found that gerrymandering in North Carolina resulted in reduced access to federally qualified health centers. ZIP codes with more gerrymandering had fewer health centers and were less likely to gain new ones, leading to longer travel distances for patients.
Researchers sequenced the genome of over 3,400 cultivated eggplant varieties and identified key agronomic traits associated with genes. The study revealed over 3,000 associations between traits and genes, providing a foundation for breeding tailor-made eggplant varieties adapted to local conditions.
Pitt researchers found that orthophosphate additions in drinking water treatment can leak into urban streams, increasing phosphorus concentrations by over 600% and trace metals like copper and iron by nearly 3,500%. The study suggests urgent corrective actions to address phosphate leakage from buried infrastructure systems.
According to a new study, humans travel for approximately 1.3 hours per day, regardless of their location or socioeconomic status. This constant travel time is influenced by psychological desires and practical limitations, resulting in a convergent range of travel times across different modes of transport.
A new study by Bayes Business School suggests that health inequalities are triggering multiple policy and finance challenges for the UK government. The paper warns that without a major drive to deter unhealthy lifestyles, health inequalities will continue to soar, exacerbating economic and social pressures.
Researchers at Gladstone Institutes and UCSF have identified the genetic switches that regulate FOXP3 levels in human and mouse cells. In humans, multiple enhancers work together to keep FOXP3 active, while a repressor keeps it off in conventional T cells. This discovery has important implications for developing immune therapies.
Researchers discovered a simple method to synthesize diverse and performant supported catalysts by alloying metals via gas-switch-triggered reduction. The new approach demonstrated 18 times higher catalytic performance than monometallic catalysts, making it suitable for industrial processes.
A new study shows that incorporating more plant-based proteins, less meat and fish, and a more diverse cereal intake into school menus can decrease the environmental footprint of meal plans. By making these changes, schools can reduce their environmental impact by up to 50%.
The EU-funded INNOVATILE project aims to reduce the environmental impact of ceramic tile manufacturing through innovative technology, targeting a 10-20% decrease in raw material and water consumption. The project also focuses on using secondary raw materials and replacing critical resources with alternative resources.
Terence Blanchard, a renowned jazz musician and composer, has received the 2025 Gutenberg Teaching Award for his exceptional teaching and mentorship. He will be visiting Johannes Gutenberg University Mainz to accept the award and participate in various events.
Dr. Christina Richey joins the SETI Institute with extensive experience in research management, strategic collaboration, and science leadership. She will focus on creating sustainable partnerships and funding opportunities to support the institute's long-term growth and mission.
A new study ranks 38 OECD countries on their progress toward global health goals, finding that some of the world's wealthiest nations lag behind smaller economies. Nations with well-integrated public health systems and preventative care achieve better outcomes for every pound spent.
The SELINA project's 6th thematic workshop brought together experts to discuss evidence-based decision-making in the public sector, focusing on practical approaches to enhance usability and policy relevance of SELINA's findings.
The European Society of Endocrinology has published a revised clinical practice guideline for the treatment of chronic hypoparathyroidism in adults, featuring a new definition and treatment algorithm. The guidelines aim to provide practical guidance for healthcare providers involved in diagnosing and managing the condition.
Four researchers from LSU's Pennington Biomedical Research Center have been named among the world's most highly cited scientists. Dr. Steven Heymsfield, Dr. Peter Katzmarzyk, Dr. Eric Ravussin and Dr. Donna Ryan are recognized for their significant and broad influence in their respective fields.
Researchers used drones to create detailed maps of a high-density nesting beach, identifying steepness and proximity to dune crossover stairs as key factors influencing turtle nesting success. The study provides insights into how changing coastal conditions affect sea turtle habitats, informing conservation policy and coastal development.
A two-year field experiment in California's Central Valley found that super-high-density olive orchards can produce high-quality oil and yields with significantly reduced nitrogen fertilizer. Compost application also improved tree nutrition and reduced greenhouse gas emissions.
The University of Maine has launched internships in AI and digital twins to prepare students for careers in the growing blue economy. Students will work with real-time data, build virtual replicas of ocean structures, and test complex marine scenarios.
Researchers discovered hidden symbols on ancient Roman glass cage cups that identify collective workshops and artisans. These 'makers' marks' provide a new perspective on the craftsmanship behind these intricate vessels.
Researchers developed a new DNA analysis technique to study old genetic samples, shedding light on disease evolution and changes in biology over time. The approach has potential for unlocking the root causes underlying shifting landscapes of modern diseases.
A magnetically guided microrobotics system enables precise drug delivery to diseased tissues, minimizing unwanted side effects. The system integrates movement, navigation, and imaging functions, ensuring seamless integration into clinical practice.
Research reveals key biological differences between women and men with long COVID, including elevated blood levels of intestinal fatty acid binding protein and reduced testosterone levels in affected women. These findings suggest potential targets for treatment that could bring relief to the 3.5 million Canadians affected.
Researchers developed a new P2D-coupled non-ideal double-layer capacitor model to analyze lithium-ion batteries under high-frequency periodic signal excitation. The model considers neglected electric double-layer capacitance and its dispersion effects, enabling more accurate mechanism analysis and performance degradation assessment.
19 St. Jude scientists were named to the 2025 list of Highly Cited Researchers, demonstrating significant influence in their investigative fields. The recognition highlights the institution's commitment to fostering big science and advancing breakthroughs in childhood cancer research.
A study in Iceland found that adding more physical education and passion project classes to a school day improves young children's well-being, reading skills, and overall school experience. The researchers discovered that this holistic approach increases enjoyment and mastery of school subjects, leading to better academic performance.
Researchers at Kyoto University create a method to produce platelet-producing cells from stem cells, offering an unlimited supply of patient-derived platelets. Monitoring KAT7 levels can help ensure efficient and consistent platelet manufacturing.
Researchers have uncovered the detailed picture of how bacteria construct carboxysomes, natural nanomachines that capture and convert CO₂. The findings reveal an unusual hexameric structure and flexible interactions with shell proteins, opening routes for bioengineering and sustainable technologies.
A new policy brief argues that current EU regulations fail to account for the risks of chemical mixtures, which can exceed safe levels even below individual substance limits. Scientists propose integrating a Mixture Allocation Factor into the REACH Regulation to regulate mixtures and improve protection of human health and the environment.
A study found that eating earlier in the day leads to significant changes in fat metabolism, whereas late eating has no measurable effect. The researchers used lipidomics and analyzed gene activity in fat tissue to understand the origin of these effects.
A University of Maryland researcher has identified cost-effective solutions for the steel industry to reduce its carbon footprint. By implementing changes such as reusing scraps and making energy-efficient upgrades, steel manufacturers can reduce global emissions by 7.2-7.8 gigatons by 2030.
Researchers found that waiting to treat narrowed coronary arteries after a heart attack is safe and can reduce the number of stent procedures. An MRI scan at a later stage can provide reassurance for patients.