The Louisiana Breast and Cervical Health Program has screened over 118,000 women since 2002, detecting nearly 1,900 cancers. The program aims to strengthen access to evidence-based screening and diagnostic services for eligible women across the state.
Researchers will examine Protein S's role in pancreatic cancer and develop new therapeutic strategies. The study aims to improve understanding of the disease and reduce mortality rates.
Researchers found that obesity and estrogen-based medications synergistically increase thrombotic risk by suppressing Protein S levels. This study offers new insights for cancer care, highlighting the need to monitor and prevent blood clots in patients with obesity or estrogen use.
A major study published in Nature Communications has identified dozens of blood proteins linked to prostate cancer risk across different populations, including African, European, Asian, and Hispanic/Latino groups. The research, led by Dr. Lang Wu, aims to improve understanding of the various causes of prostate cancer across populations.
Researchers at the LSU LCMC Health Cancer Center have identified key immune differences in triple-negative breast cancer, a leading cause of breast cancer deaths among Black women. The study provides new insights that could lead to more effective and personalized treatments for this aggressive form of cancer.
African Americans are disproportionately affected by lung cancer, with lower rates of diagnosis and treatment compared to white individuals. The new research project aims to combine lung cancer screenings and smoking cessation to increase application and cessation behaviors among this population.
Researchers identified Elovanoid-34, a molecule that modulates the activity of TXNRD1 protein, which regulates antioxidant defenses. This discovery opens new therapeutic avenues for degenerative brain and eye diseases, as well as promoting healthy aging.
Rahn Baily, MD, has made significant contributions to the field of psychiatry and healthcare reform through his research on health disparities, violence, and mental illness. He will receive the prestigious Solomon Carter Fuller Award for his outstanding achievements in addressing pressing societal needs.
A clinic-based community program improved food security scores, healthy eating behaviors, and depression scores in a vulnerable, food-insecure population. The Geaux Get Healthy Clinical Program provided comprehensive education and access to resources, leveraging community partnerships.
Researchers found that administering precursors of Elovanoids improved neurological deficit in an experimental model of ischemic stroke. The study identified a cascade of gene responses and sheds light on potential new therapeutic avenues for treating ischemic strokes.
The grant aims to recruit, enroll, educate, and graduate undergraduate students from minority backgrounds and increase faculty diversity. By enhancing curricula with student support services and collaborative partnerships, the program seeks to reduce health disparities and provide culturally aligned care.
A recent study published in the Journal of Diabetes Science and Technology found that HbA1c levels are markedly higher in young black youth compared to whites with type 1 diabetes. This disparity can lead to increased risk of hypoglycemia and long-term complications if primarily used for insulin management.
A new approach to PTSD treatment may involve targeting cerebellar inhibitory interneurons, which play a critical role in fear memory formation. The research found that these interneurons drive fear memory consolidation via learning-induced HCN plasticity.
A first-of-its-kind study by LSU Health New Orleans found that chronic diseases, such as hypertension and diabetes, explained nearly two-fifths of the racial disparity in COVID-associated hospitalizations. Non-Hispanic Black cancer patients had a higher prevalence of chronic diseases and were more than twice as likely to live in high-p...
Age-related macular degeneration (AMD) decreases essential fatty acid docosahexaenoic acid (DHA), limiting protective molecule formation and repair potential. The discovery may open new therapeutic avenues for AMD, particularly in females, who are more susceptible to retinal degeneration due to estrogen effects.
LSU Health researchers found combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases effectiveness in experimental models of ER+ and TNBC. The study's findings suggest a new approach for treating treatment-resistant breast cancers.
Researchers found that African ancestry patients with dilated cardiomyopathy have fewer clinically actionable variants in DCM genes compared to European ancestry patients. The study enrolled 1,198 patients with dilated cardiomyopathy, revealing a racial imbalance in genetic trials for heart failure.
Dr. Eric Lazartigues has been recognized for his groundbreaking research on salt-sensitive hypertension and the role of the brain renin-angiotensin system in regulating blood pressure. His work has led to a deeper understanding of hypertension's impact on cardiovascular diseases and mortality.
LSU Health New Orleans' School of Nursing has been awarded $2.6 million by the Health Resources and Services Administration to increase nurse practitioners and midwives trained for underrepresented populations, particularly in rural areas. The funding will also enhance curriculum and provide tuition support.
LSU Health New Orleans researchers found that a combination therapy using Neuroprotectin D1 and Resolvin D1 boosted brain cell survival, growth, and stability. The therapy showed promising results in reducing lesion volume and improving neurological function in acute ischemic stroke models.
A new study published by LSU Health New Orleans found that a diet high in fruits, dark-green vegetables, and beans can significantly lower the risk of genital high-risk-HPV infection, which is associated with cervical cancer. The research also showed that women who eat healthily tend to practice other healthy behaviors.
A rapid diagnostic test for sepsis has been validated in the emergency department, providing a reliable aid for early detection. The study found that the test improved sepsis triage and reduced time to diagnosis, leading to better patient outcomes.
The National Institutes of Health has awarded a $1.4 million Postbaccalaureate Research Education Program (PREP) grant to LSU Health New Orleans. The program aims to enhance the diversity of the biomedical sciences research workforce by preparing individuals from underrepresented backgrounds for PhD degree programs.
The LSU Health New Orleans Louisiana Tumor Registry released the sixth report of statewide cancer incidence rates by census tract, finding that 81% of tracts met criteria for all cancers combined. Census tracts with statistically higher incidence rates were found in parishes including Orleans, Lafourche, and St. Bernard.
A new LSU Health New Orleans study suggests that single, focused Interprofessional Education-based exercises can significantly decrease stigma associated with alcohol use and improve knowledge and confidence in screening for Alcohol Use Disorder (AUD). The exercise led to substantial improvements in student understanding of AUD risks, ...
A novel surgical pain management strategy has been developed to reduce opioid use after total knee arthroplasty. The study found that changing prescriptions for opioids at discharge from automatic to upon request dramatically decreased opioid use, with over half of patients recovering without opioid use.
Angelo J. Mariotti, the new Dean of LSU Health New Orleans School of Dentistry, has a track record of success in transforming dental education, increasing fundraising, and improving facilities. He aims to enhance faculty development and expand clinics to serve Louisiana's citizens for better oral health.
A study published in the American Journal of Preventive Medicine estimates the economic burden of acute firearm injuries at a Level I Trauma Center in New Orleans, resulting in a net loss of $20.3 million over four years. The study highlights the significant financial impact of gun violence on healthcare systems and society.
Researchers at LSU Health New Orleans have identified a new drug target for triple-negative breast cancer, which lacks estrogen and progesterone receptors. The novel small molecule inhibitor NSC33353 works synergistically with doxorubicin to suppress the growth of TNBC cells.
A landmark study published in The Lancet found that chlorhexidine gluconate and povidone-iodine aqueous solutions are equally effective in preventing surgical site infections in patients with open fractures. This finding has significant implications for healthcare practitioners and may reduce costs associated with accessing these antis...
WayPath Pharma has been awarded a $225,000 Phase I Small Business Technology Transfer (STTR) award to develop new metabolic drugs targeting tumor stem cells and crossing the blood-brain barrier. The funding aims to advance treatment options for glioblastoma, a highly aggressive brain cancer with limited treatment options.
The $3M award will create a Clinical Nurse Educator Academy for Region 6, increasing RNs and APRNs in medically underserved communities. The program aims to improve health equity and access to quality care through competency-based education and recruitment of licensed nurses.
LSU Health New Orleans has been awarded $4.6 million to develop a Burn Prehospital Provider Program, which will provide education and training for military and civilian healthcare providers in different environments. The program aims to improve burn injury care before patients reach a hospital.
Researchers at LSU Health New Orleans have identified a critical immunosuppressive pathway and developed an experimental inhibitor to protect T-cells from weakening. The CBL-B inhibitors show great potential in enhancing the efficacy of cancer immunotherapy, making patients' T-cells more effective in killing cancer cells.
Research led by Drs. Yuhai Zhao and Walter J Lukiw reports a pathway from the gut to the brain that contributes to Alzheimer's disease development. Adequate dietary fiber intake can prevent this process. The study suggests a potential means to modify the abundance of microbes in the microbiome.
A recent study published in The Journal of Bone and Joint Surgery found that only 35.9% of articles reported patient race, 15.4% reported ethnicity, and 8.3% reported income. Including demographics in multivariable analyses is crucial to determine the applicability of study results to diverse patient populations.
Researchers have found that treating high-grade squamous intraepithelial lesions (HSILs) in people with HIV significantly decreases the progression to anal cancer. The ANCHOR trial enrolled over 4,000 participants and showed a 57% reduction in anal cancer cases.
The new human cell line, ABC, was developed from retinal pigment epithelial cells and retains their properties, allowing for the study of events relevant to normal repair processes. The research may lead to discoveries in senescence gene programming, neuroprotection, and cellular replacement therapies for blinding eye diseases
Researchers at LSU Health Sciences Center have discovered a novel combination therapy that effectively treats chemo-resistant triple-negative breast cancer. The treatment combines two existing FDA-approved drugs, ceritinib and enzalutamide, to target the growth of cancer cells, showing promise for improving treatment outcomes.
A randomized, placebo-controlled pilot study found that NB-UVB phototherapy decreased mortality in hospitalized COVID-19 patients with no adverse events reported. The treatment was effective in both vaccinated and unvaccinated patients, with reduced pathologic inflammation and improved intracellular killing of pathogens.
The program aims to increase trained cancer researchers in Tanzania and prepare them for HIV-associated cancer diagnostics, genomics, and therapy. It will focus on molecular detection, epidemiology, and biology of common HIV-associated malignancies.
Researchers found that low-density neutrophils are associated with chronic inflammation in obesity, which can lead to comorbidities like type 2 diabetes and cancer. Bariatric surgery reduces these cells in circulation, improving metabolic syndrome components.
A study found a shift in the profile of specialized lipid mediators from pro-resolving to pro-inflammatory in patients with cognitive impairment, correlating with severity of cognition impairment. The researchers identified novel mechanisms of brain health and potential therapeutic targets for slowing down Alzheimer's disease onset.
Researchers at LSU Health New Orleans and Karolinska Institutet found that intranasal application of pro-resolving lipid mediators arrested memory loss and brain degeneration in an experimental Alzheimer's model. This discovery opens up new possibilities for therapeutic interventions for Alzheimer's disease.
Researchers found that repetitive exposure to environmental hypoxia prevented memory loss and reversed impairments in nerve-to-nerve communication. Adult offspring also inherited this protection against dementia.
The Nutrition for Precision Health study will use data from 10,000 participants to develop algorithms predicting individual responses to food and dietary routines. The goal is to create more personalized nutrition recommendations and reduce health disparities.
A study led by LSU Health found how late-onset retinal degeneration develops and identified a surprising potential therapeutic, metformin. The research suggests that an enzyme called AMPK activates the protein CTRP5 to regulate fatty acid metabolism and energy stability.
A LSU Health New Orleans study reports a nearly 70% decrease in morphine milligram equivalent (MME) per discharge opioid prescriptions for patients who underwent common lower extremity surgical procedures. The study also found a significant decline in new opioid prescriptions, from 50% in 2013 to 19.3% in 2018.
A recent review reveals alarming increase in physician burnout among diagnostic radiologists, with causes including lack of control, social isolation and technological demands. Possible solutions include heightened engagement, dedicated reading room assistants and mindfulness techniques.
Researchers at LSU Health have rediscovered the correct anatomy of the hip muscles, finding that they do not join into a single tendon but instead attach to different regions. This discovery has significant implications for understanding the evolution of human upright gait and bipedal locomotion.