The USPSTF recommends that clinicians offer or refer adults without cardiovascular disease (CVD) risk factors to behavioral counseling interventions promoting a healthy diet and physical activity. This recommendation aims to reduce the burden of CVD by encouraging lifestyle modifications.
A new study co-authored by economist Dr. Reto Odermatt found that educational and occupational aspirations are important predictors of career success, with ambitious goals motivating people to invest more in their future career success. However, unrealistically high aspirations as a teenager can have negative effects on well-being as a...
A new AI program identified four variables for a swinging double-pendulum, but the remaining two variables remain a mystery. The AI successfully predicted physical phenomena in other systems, such as air dancers and lava lamps, with varying numbers of variables.
Researchers have found correlations between retina and brain structures altered in Alzheimer's disease in healthy subjects at risk. These findings suggest the retina may provide information on brain state and changes, paving the way for new diagnostic tools.
Researchers at University of Queensland have found that native New Zealand stinging tree toxins activate pain receptors differently than Australian counterparts, offering potential for novel pain medication. The study aimed to understand pain pathways and tackle chronic pain effectively without side effects and addiction.
A study published in Journal of Virology reveals that primary cells from various bat species do not support SARS-CoV-2 replication, even those expressing ACE2, a key receptor for the virus. This finding contradicts previous theories about bats as potential reservoirs of the virus.
A new study led by Dartmouth researchers provides the clearest understanding yet of supermassive black holes' life cycles. By analyzing X-ray telescope data and a new data analysis technique, scientists found that accretion rates vary significantly depending on how obscured an object is by gas and dust ring.
A recent study published in The Journal of Bone and Joint Surgery found that only 35.9% of articles reported patient race, 15.4% reported ethnicity, and 8.3% reported income. Including demographics in multivariable analyses is crucial to determine the applicability of study results to diverse patient populations.
Patient-centered medical homes can bring meaning to healthcare by focusing on individualized outcomes and personal growth. By incorporating narrative medicine and goal-oriented care, primary care physicians can transform practices into truly person-centered models of care.
Scientists have developed a novel method to probe the longitudinal distribution of light-matter interaction in gap-mode plasmonic nanocavities. By embedding monolayer MoS2 as an emitter in the nanogap, they achieve spatial resolution of ~1 nm and observe significant photoluminescence enhancement factors up to 2800 times.
A study published in JAMA found that FDA warning letters resulted in increased product recalls and the removal of prohibited drugs from dietary supplements. The investigation aimed to assess the frequency of recalls and presence of FDA-prohibited substances after issuing warning letters.
A new 'optofluidic' system designed at the University of Toronto Engineering can enable buildings to save energy by dynamically changing the appearance of their exteriors. The system uses carefully controlled fluid injections to create a dynamic shading system, reducing the need for heating, cooling and lighting systems.
Researchers have identified a molecular mechanism behind worm olfaction, revealing how they discriminate between over 1,300 scents despite having only 32 olfactory neurons. The discovery involves the conserved protein arrestin, which helps fine-tune multiple sensations in both worms and humans.
A cross-sectional study found that the elderly's daily step count and physical activity level are strongly influenced by the number of places they visit, not just their out-of-home time. The researchers suggest that encouraging outings to diverse locations can be a healthier approach than simply going for longer periods.
Researchers at ITQB NOVA and iMM discovered that the parainfluenza fusion peptide promotes membrane fusion by destabilizing the host's membrane and forming clusters of oligomeric structures. This breakthrough can contribute to developing antiviral therapies to prevent infection.
A study analyzing Twitter data from May 2020 to January 2021 found that the share of tweets about healthy foods increased by 20%, while fast-food and alcohol tweets decreased by 9% and 11%, respectively. The study suggests that people may have made healthier dietary changes during the pandemic, depending on their neighborhood environment.
Researchers at the University of Tsukuba found that allowing cross-border evacuations can reduce evacuation time by 14% and improve public safety. However, intermunicipal cooperation is required to make this approach effective.
Researchers confirm COVID-19 originated from live animals sold at Huanan Seafood Wholesale Market in Wuhan, China. The market was the epicenter of the epidemic, with vendors getting infected first and setting off a chain of infections.
Researchers at RCSI University have created a new lab-based model to test devices for heart failure with preserved ejection fraction. The model enables testing of the left atrium and ventricle, two independently controlled chambers that simulate blood flow during the resting phase.
Researchers have created a new glass-ceramic that emits light in response to mechanical stress, enabling potential applications for monitoring stress in artificial joints and structures.
A Rutgers study found that a Yoga of Immortals mobile app significantly improves urinary incontinence symptoms in people practicing for four weeks. The app-based intervention engages the pelvic floor and specific energy centers, leading to reduced frequency and severity of urine leaks.
Researchers at UNSW Medicine & Health unveil a simple mathematical model predicting DNA hybridization rates based on nucleating interactions. The discovery has the potential to improve understanding of biological systems and refine nanotechnologies.
Nancy R. Hooyman, a renowned gerontologist, has received the 2022 Donald P. Kent Award from the Gerontological Society of America (GSA) for her outstanding leadership in promoting gerontological education and research.
A team of researchers at Osaka University has created a machine learning system that can virtually remove buildings from a live view, streaming in real-time on a mobile device. This technology can help accelerate the process of urban renewal based on community agreement, reducing conflicts and delays.
A large study suggests that differences in growth, weight, and body fat levels among children conceived through fertility treatment are small and not apparent by late adolescence. The study found minimal health implications from these differences.
The American Academy of Family Physicians has been awarded a $31 million funding to conduct a large-scale study on the comparative effectiveness of asthma treatments. The study will focus on inhaled steroids and specific antibiotics, alone or together, in over 3,000 patients with asthma aged 12 and over.
Binghamton University researchers have developed a way to turn CDs into flexible biosensors that can monitor electrical activity in human hearts and muscles, as well as lactate, glucose, pH, and oxygen levels. The sensors are fabricated in 20-30 minutes without toxic chemicals or expensive equipment, costing around $1.50 per device.
A new study found that experiencing the death of a spouse due to COVID-19 may be worse for mental health than deaths from other causes. People who lost a spouse to COVID-19 were more likely to report symptoms of depression and loneliness. The study underscores the ongoing health risks posed by the pandemic, even to those who have not b...
A study found that certain bacteria grow more efficiently on plastic bags than leaves and twigs, breaking down carbon compounds in the process. The bacteria's growth is stimulated by plastic pollution, which primes them for rapid breakdown of other natural carbon compounds.
A study of over 500 patients with multiple myeloma reveals a high prevalence of genetic alterations in oncogenic pathways, leading to treatment resistance. The research found a specific link between RASopathies and mutations in these pathways, offering new insights into the development of resistance mechanisms.
Public health researchers developed an interactive web-based guide to support family physicians in addressing COVID-19 vaccine concerns. The guide provides resources to counsel patients on safety, co-morbidities, conspiracy theories, and other issues, promoting better conversations and vaccine uptake.
A study found that bird photography decreases nest predation and boosts nestling survival in tropical forests. Researchers discovered a significant reduction in predation rate among photographed nests, with little effect on feeding rates.
Despite electronic health records and care coordination efforts, communication gaps between primary care and specialist physicians persist, with 22% of PCPs sending information rarely or never at referral times. This delay can lead to delayed diagnoses, unnecessary testing, and patient dissatisfaction.
A study of 17 African coastal countries found that those farther from the coast have lower standards of living, with fewer owning radios, TVs, and vehicles. Access to education and infrastructure are key factors in increasing prosperity near ports.
A new study published in the Journal of the Academy of Marketing Science found that boosting diverse program offerings and investing in advertising can improve racial and income representativeness. Government funding had the greatest positive effect on DEI, followed by foundation funding.
A new 'joint avatar' study reveals that visual information predicting a partner's intentions significantly enhances sense of embodiment towards partner-controlled limbs during virtual co-embodiment. This finding may contribute to enhancing embodiment towards autonomous prosthetic limbs, reducing user discomfort related to lack of control.
A committee of distinguished scientists will meet to lay out a vision for the future of high-energy physics, building on decades of planning by the American Physical Society. The meeting aims to identify research questions, directions, and tools for advancing our understanding of the universe.
A new study estimates that exposure to PFAS chemicals may result in $5.5-63 billion in lifetime health costs due to conditions like low birth weight, childhood obesity, kidney cancer, and hypothyroidism. The study supports the EPA's decision to lower safe allowable levels of these substances.
Researchers have developed novel 3D atomic force microscopy (AFM) probes with improved designs, materials, and production processes. The new probes enable high-resolution, high-speed AFM imaging under air and liquid environments, opening doors for advanced applications in fields like biomedical sciences.
Researchers at PETA Science Consortium International successfully transitioned a human lung cell line to animal-free media, improving reproducibility and relevance of studies. This achievement sets a precedent for transitioning other cell types, offering far-reaching implications for the field of in vitro research.
According to a new poll, nearly 40% of older adults (50-80) use at least one integrative medicine strategy to alleviate symptoms or relax. However, only 18% discuss these strategies with their healthcare providers. The poll highlights the importance of primary care clinicians discussing integrative approaches with patients.
New research finds that firms stage data breach announcements around significant news to reduce media coverage and market impact. This strategy harms consumers by not adequately 'punishing' firms for their misbehavior, suggesting shorter disclosure deadlines be mandated.
A new study has found that testing for cyclin-dependent kinase inhibitor protein (p16) in biopsy tissue can help more accurately identify IPF. High expression of p16 is associated with worse outcomes and reduced survival, emphasizing the need for early treatment.
A new study found that consuming green tea extract for four weeks can lower blood sugar levels, improve gut health, and decrease inflammation in healthy individuals and those with metabolic syndrome. Researchers observed a significant reduction in fasting blood glucose levels and decreased gut permeability.
Researchers at Kyoto University have developed the smallest nanodiamonds capable of detecting temperatures on the nanoscale inside cells and organelles. These nanodiamonds utilize silicon-vacancy color centers to gauge luminescence, enabling precise temperature sensing with sub-kelvin accuracy.
A Spanish study combines genetic and imaging data to predict patient prognosis, identifying those at risk of malignant arrhythmias or severe complications. The findings open the way for personalized medicine in treating dilated cardiomyopathy.
A new study published in JAMA Internal Medicine found that an alert about a shortage of blood test tubes led to a significant reduction in unnecessary blood clotting tests. The study suggests that similar interventions could reduce low-value care and promote wise use of medical tests.
Scientists have discovered that there is enough lithium in unconventional water sources to make extraction worthwhile. The composition of these sources affects the performance of emerging electrochemical intercalation technology, providing insights for refining and optimizing it.
A multicenter study found that preterm children with bronchopulmonary dysplasia who attend daycare are more likely to visit the emergency department, use systemic steroids, and experience chronic respiratory symptoms. The risk of these complications is highest in infants under 1 year old and may persist until 36 months of age.
A study published in Annals of Internal Medicine found that telehealth can improve clinical outcomes and patient satisfaction for pregnant mothers and their infants. The researchers analyzed 28 randomized controlled trials and 14 observational studies to assess the effect of telehealth-delivered care on maternal health outcomes.
Newborn marmosets practice face and mouth movements needed to call for help before birth. Human-like crying movements have been observed in the womb, suggesting a potential link between primate and human vocal development.
Researchers used Plasmodium falciparum 7G8 challenge trials to test the PfNF54-based PfSPZ Vaccine, providing conservative predictions of its efficacy in Africa. The study found that VE over 24 weeks was as good as or better than VE against Pf7G8 CHMI at 24 weeks.
A Japanese study reveals that policy disagreement and politicization led to the split of Japan's largest opposition party in 2017. The researchers found that traditional DIF analysis failed to capture the complexity of party positions, but a corrected version showed strong discord over defense policy.
Researchers from Helsinki and Ural Federal Universities group atmospheric halos into commonly observed and rare categories. They identified conditions necessary for seeing optical illusions in the atmosphere, such as temperature and humidity, but still struggle to explain some exotic forms like elliptical halos and Moilanen arc.
A study found that plant genetic variability controls specific microorganisms, influencing microbial community composition and plant reproductive success. The research used Arabidopsis thaliana genotypes and metabarcoding DNA sequencing to analyze the impact of genetics on leaf microbiota.
Researchers at Moffitt Cancer Center used mathematical modeling to study the impact of tumor size, immune cell populations, and interactions on cancer treatment outcomes. The models predicted optimal therapeutic approaches for different types of therapies, including cytotoxic chemotherapy and immunotherapies.
Pediatric kidney transplant recipients with high tacrolimus intrapatient variability are at increased risk of developing antibodies against the transplanted kidney. This variability can be identified through hospital electronic health records, allowing for early intervention to prevent rejection and improve graft outcomes.
Despite electronic health records, gaps in communication between primary care physicians and specialist physicians persist. The study found that 22% of PCPs report sending clinical information to specialists at the time of referral, and less than 35% receive information back after consultation.
The report proposes a health equity framework to address disparities in telehealth services, focusing on strategic priority, patient input, social determinants, and institutional racism. It calls for integrating equity and innovation efforts to ensure access to telemedicine and digitally enabled health tools.
Researchers identified CUDC907 as a dual phosphoinositide-3 kinase/histone deacetylase inhibitor that promotes apoptosis in NF2 schwannoma cells. The compound reduced viability and induced cell cycle arrest in human merlin deficient Schwann cell models.
A recent study by Renmin University of China found that a good media reputation consistently reduces the risk of termination for administrative agencies. The research analyzed over 4.95 million articles published between 1949 and 2019 in the People's Daily, an official newspaper of the Chinese Communist Party Central Committee.
The study establishes a scientific reporting quality metric to assess rigor and transparency, highlighting the need for high-quality reporting to ensure replicability. The latest version of the Rigor and Transparency Index (RTI) scores significantly lower than replication studies, emphasizing the need for improvement.
A recent study published in the European Respiratory Journal found that children who grow up near green spaces have better lung function. The research suggests that increasing exposure to vegetation close to home can improve lung health, especially when combined with other factors such as physical activity and reduced air pollution.
Scientists reprogrammed stem cells to create models of diseased eye cells, analyzing DNA, RNA, and proteins to pinpoint genetic signatures. The study identified 439 molecular signatures associated with AMD, including potential new gene variants that target mitochondrial proteins.
A recent study found that people who smoke or vape prior to hospitalization for COVID-19 are more likely to experience severe complications, including death. The study, which analyzed data from the American Heart Association's COVID-19 CVD Registry, also showed that young individuals are particularly at risk.
A study analyzing 2.8 million SARS-CoV-2 genomes reveals six gene-level mutations that have reached saturation, suggesting future variants are combinations of existing high-frequency mutations. The team also identifies 185 mutations positively correlated with viral transmission rates.
Researchers discovered that REM sleep disturbances are linked to increased risk of drug relapse, and that targeting MCH neurons may be a promising therapeutic approach. The study found that improving REM sleep reduced cocaine-seeking behavior in rats.
A long-term marine conservation effort in the US Virgin Islands has helped recover a key fish species, the red hind, with average fish size increasing by over 35% and population reaching sustainability. The recovery is attributed to management decisions and adherence to fishing closures.
Researchers found that the SARS-CoV-2 virus likely jumped from animals to humans at least twice and possibly as many as two dozen times at the Huanan Seafood Wholesale Market in Wuhan, China. The market's genetic diversity suggests multiple spillover events occurred, with at least two strains making successful introductions.
The recently updated ICPC-3 guide provides health professionals with a better understanding of patient functioning and its impact on primary healthcare. By implementing ICPC-3, clinicians can improve data documentation, enhance information exchange, and ultimately provide more effective care to patients.
A new study by University of California - San Francisco-led researchers found that tweens who spend more time on screens have a higher likelihood of developing disruptive behavior disorders. Social media was most likely to be linked to conduct disorder, while other forms of screen use were associated with oppositional defiant disorder....
The first global dataset of SARS-CoV-2 infections in animals has been published, providing a comprehensive overview of the virus's impact on animal populations worldwide. The dataset shows an increasing number of reported cases globally, with high diversity of variants detected in various species.
A new study reveals that subsurface ocean warming in the subpolar North Atlantic caused Heinrich Events, which led to ice sheet instability and disruption of the Atlantic Meridional Overturning Circulation. The warming facilitated melting of polar ice sheets from below, resulting in accelerated shedding of icebergs.
A study of up to 158,000 infants found those conceived via assisted reproductive technology were shorter, lighter, and thinner from infancy to early adolescence. Differences decreased with age, but the findings suggest a long-term impact on growth and body composition.
Researchers developed a protocol to distinguish information scrambling from decoherence in quantum systems. By evolving a system forward and backward through time, they can measure the preservation of information scrambling and detect losses due to decoherence.
Researchers developed a computer model to investigate complex fluids and droplet formation in living cells. The study reveals that even weak interactions can lead to robust emergence of complex behavior, such as droplet formation, which has significant implications for understanding cellular mechanisms.
A new visualization tool combines clinical and home blood pressure readings to aid in blood pressure management. It enhances shared decision-making between doctors and patients by integrating at-home readings with electronic health records.
Research teams at Mass General Brigham will conduct large-scale studies to treat acute suicidal depressed state and bipolar depression. The studies aim to compare the effectiveness of various treatments and provide valuable data on treatment outcomes.
An international team of researchers found that the earliest cases of COVID-19 arose at a wholesale fish market in Wuhan, China, linked to bats, foxes, and other infected live mammals sold as meat or fur. The study confirms earlier reports suggesting animal sales were the source of the pandemic.
Researchers found similar operational procedures for remote medication abortion services across diverse practice settings, with adaptations made to local laws and regulations. The study highlights the feasibility of offering abortion services through telehealth, demonstrating potential variations in service adaptation.
Researchers found that cocoa flavanols lower blood pressure and arterial stiffness only when the blood pressure is high, not at normal levels. This discovery paves the way for potentially using cocoa as a treatment for raised blood pressure in clinical practice.
A new study published in the Journal of Clinical Oncology found that frequent aspirin use is linked with a 13% reduced risk of ovarian cancer in individuals with multiple risk factors. Aspirin benefitted most subgroups, including those with endometriosis and obesity.
Adults with chronic kidney disease are more likely to have a low intake of fruits and vegetables compared to similar individuals without the condition. This study suggests that increasing fruit and vegetable consumption may be beneficial for overall health.
The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling $258 million to support 26 new research studies. These studies aim to fill evidence gaps and improve healthcare decision making for a range of high-burden conditions, including mental health, heart conditions, asthma, bone fractures, and sinus...
A Dartmouth-led study found that urban gardens with rare plant species tend to attract rare bee and bird species. Women, older gardeners, and those living near the gardens are more likely to curate these rare plants, suggesting a cascading effect on biodiversity.
The new AI system uses associative learning to detect similarities in datasets, reducing processing time and computational cost. By leveraging optical parallel processing and light signals, the system can identify patterns and associations more efficiently than conventional machine learning algorithms.
A study of 17,000 US primary care patients with COPD found 49.9% experiencing multiple exacerbation episodes despite treatment. Patients reported high symptoms and breathlessness, highlighting the need for non-pharmacologic treatments and improved physician education.
The partnership aims to enhance early detection and reporting for emerging diseases, building a robust decentralized global surveillance network. The collaboration will focus on advancing equitable data-sharing practices, bolstering epidemiological and genomic surveillance in low- and middle-income countries.
Researchers developed an EHR-embedded card study to replace traditional paper-based methods in clinic-based research. The digital tool increased efficiency and reduced labor costs, as each participant's responses were linked to clinic and patient data.
Researchers at Stanford University developed a custom molecule sBCMA-Fc V3 that inhibits the growth of both multiple myeloma and diffuse large B cell lymphoma in mice. The molecules were found to be nontoxic in monkeys, suggesting they could be used to treat humans with these deadly diseases.
A study published in the European Heart Journal found that making small behavioral changes can significantly reduce cardiovascular risk. Participants who received a lifestyle intervention showed improvements in physical activity, diet, and sedentary time, leading to decreased blood pressure and cholesterol levels.
A UC Berkeley-led study identified specific human lung proteins that can promote or protect against SARS-CoV-2 infections. Researchers found that mucins, a key component of mucus in the lungs, help block the virus from entering cells, while other mucins may even promote infection.
Researchers analyzed data from over 50 years of US medical schools to identify trends in gender equality in rank and tenure. Despite consistent increases, current trends do not predict achieving gender parity for four decades in some ranks.
A multidisciplinary study uses magnetometers to investigate the magnetic fields of metropolitan areas, finding that each city has a distinct magnetic signature. This unique characteristic can be exploited to analyze anomalies in city operation and long-term trends of urban development.
Researchers found that the Huanan market in Wuhan, China was the early epicenter of the COVID-19 pandemic, with SARS-CoV-2 likely present in live mammals sold at the market. The studies suggest two separate zoonotic transmissions led to the virus's introduction into humans.
A Dartmouth-led research team will assess the effectiveness of visit information provided to older adult patients and caregivers in improving quality of life. The CHRONICLE Trial aims to determine whether audio recordings or written summaries are more effective in sharing healthcare visit information.
A new University of Michigan study found that people with a parent with a history of alcohol problems are at greater risk for showing signs of addiction to highly processed foods. Diets dominated by these foods contribute to preventable death worldwide.
Two studies suggest the COVID-19 pandemic originated from animal-to-human transmissions at the Huanan Seafood Wholesale Market in late November 2019. Genetic and geographic analyses pinpoint the market's western portion, where live animals were sold, as a key location for early cases.
A new study within the Veterans Health Administration system identified effective strategies to reduce benzodiazepine prescriptions for older adults. The researchers found that initiatives focusing on passive strategies like education and patient identification have limited success in lowering prescription rates.
The article highlights the need for consistent measurement of social determinants of health (SDOH) interventions in the healthcare industry. The authors argue that increased funding and disjointed management strategies have led to a growing number of companies addressing SDOH, but little focus has been placed on rigorous evaluation of ...
University of Iowa researchers confirmed a specific brain region, the subthalamic nucleus, plays a critical role in governing mind-body communication for motor control. The study could advance treatment options for Parkinson's disease, a disorder characterized by declining motor coordination.
Clinicians perceive electronic health records as a barrier to patient engagement, maintaining less eye contact and feeling less personal during visits. However, most patients report a positive experience with EHR use, indicating sufficient clinician-patient interaction.
The heaviest neutron star detected has consumed nearly all the mass of its companion, growing into a record-breaking object. The study provides constraints on matter's behavior at extreme densities, potentially excluding exotic states of matter.
A study found that individuals with less hippocampus engagement are more likely to develop severe posttraumatic stress disorder (PTSD) symptoms. Those who exhibit greater defensive reactions to potentially threatening events also showed increased PTSD risk.
Researchers found shadowed areas within lunar pits that maintain a comfortable temperature of around 63 degrees Fahrenheit, making them suitable for human habitation. The discovery could provide safer base camps for lunar exploration and long-term stays.
The COVID-19 pandemic led to a pronounced decline in the methadone supply but no disruption to the buprenorphine supply. The study highlights the vulnerability of opioid treatment infrastructure during public health crises.
Researchers developed an on-chip spectrometer and silicon nanowires to extract light's angle, spectrum, and other aspects, enabling multimodal imaging. The advancements could enhance autonomous vehicles' vision, biomedical imaging, and telescopes' ability to see through interstellar dust.
Researchers have identified a group of deregulated genes in pancreatic cancer that may serve as potential therapeutic targets. These long non-coding RNAs, when silenced, reduced tumor aggressiveness and characteristics such as proliferation and invasion.
Dinosaurs had high metabolic rates, suggesting they were endotherms, which allowed them to regulate their body temperature. This finding refutes previous ideas that dinosaurs were intermediate between ectotherms and endotherms.
Researchers say stereotypes and stigma surrounding mental illness can lead to poor workplace behavior. Employees with mental illnesses may face fear of discrimination, which drives inauthenticity and counterproductive work behaviors.
A new study reveals that reef fish diversity is driven by a recent innovation among bony fish – feeding by biting prey from surfaces. This feeding method allowed fish to access diverse new prey, promoting the evolution of a wide variety of body shapes and a high rate of diversification.
A study published in Nature Communications describes the performance of GTRx, an automated disease management system that integrates rapid Whole Genome Sequencing diagnosis with analysis pipeline. The system provides clinical decision support to guide physicians in selecting optimal therapies for critically ill infants and children.