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To trigger Crohn’s disease, pathogenic bacteria co-opt a genetic susceptibility

12.01.22 | Weill Cornell Medicine

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Dr. Randy Longman
Dr. Randy Longman, Associate Professor of medicine in the Division of Gastroenterology and Hepatology and the director of the Jill Roberts Center for Inflammatory Bowel Disease at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center. Credit: Weill Cornell Medicine

Cell

Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis

15-Nov-2022

Additional Media

Dr. Steven Lipkin
Dr. Steven Lipkin, Vice Chair for research in the Weill Department of Medicine at Weill Cornell Medicine and a medical geneticist at NewYork-Presbyterian/Weill Cornell Medical Center Credit: Weill Cornell Medicine

Keywords

Bacterial Genetics Crohn Disease Developmental Genetics Disease Susceptibility Drug Therapy Gastroenterology Inflammatory Response

Article Information

Journal
Cell
Article Publication Date
2022-11-15
Article Title
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis

Contact Information

Barbara Prempeh
Weill Cornell Medicine
bap4004@med.cornell.edu

Source

Original Source
https://news.weill.cornell.edu/news/2022/12/to-trigger-crohn%E2%80%99s-disease-pathogenic-bacteria-co-opt-a-genetic-susceptibility

How to Cite This Article

APA:
Weill Cornell Medicine. (2022, December 1). To trigger Crohn’s disease, pathogenic bacteria co-opt a genetic susceptibility. Brightsurf News. https://www.brightsurf.com/news/LN274MK1/to-trigger-crohns-disease-pathogenic-bacteria-co-opt-a-genetic-susceptibility.html
MLA:
"To trigger Crohn’s disease, pathogenic bacteria co-opt a genetic susceptibility." Brightsurf News, Dec. 1 2022, https://www.brightsurf.com/news/LN274MK1/to-trigger-crohns-disease-pathogenic-bacteria-co-opt-a-genetic-susceptibility.html.