Tobacco is a known risk factor for the misuse of prescription opioids. In addition, concurrent use of opioids and sedative-hypnotics is a risk factor for opioid overdose or addiction. In an American Journal on Addictions study, tobacco users were more likely to receive prescriptions for opioid analgesics with muscle relaxants and/or benzodiazepines than people who did not use tobacco.
The findings, which come from an annual survey of visits to office-based physicians in outpatient settings in the United States, suggest that appropriate caution should be exercised while co-prescribing opioid analgesics with muscle relaxants and/or benzodiazepines among tobacco users to prevent prescription drug addiction.
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American Journal on Addictions