An accompanying commentary by Thomas Decker, of the University of Vienna, provides an overview of Toll-like receptors, their role in bacterial infection, and a discussion of the potential strengths and weaknesses of targeting these receptors for combating sepsis.
TITLE: Antagonistic antibody prevents toll-like receptor 2–driven lethal shock-like syndromes
AUTHOR CONTACT:
Carsten J. Kirschning
Technical University of Munich, Munich, Germany.
Phone: +49-89-4140-4132; Fax: +49-89-4140-4139; E-mail: carsten.kirschning@lrz.tum.de
View the PDF of this article at: http://www.jci.org/cgi/content/full/113/10/1473
ACCOMPANYING COMMENTARY: Sepsis: avoiding its deadly toll
AUTHOR CONTACT:
Thomas Decker
University of Vienna, Vienna, Austria.
Phone: +43-1-4277-54605; Fax: +43-1-4277-9546; E-mail: thomas.decker@univie.ac.at
Journal of Clinical Investigation