According to a study of more than 10,000 UK Biobank participants, ages 40-69, gray matter volume in certain subregions of the default mode network (DMN) was associated with variations in white matter microstructure in the fornix, the major output tract of the hippocampus, whereas among other DMN subregions, functional coupling patterns were associated with connectivity changes between other major brain networks; such an architecture might facilitate the DMN's role in advanced cognition.
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Article #18-04876: "Subspecialization within default mode nodes characterized in 10,000 UK Biobank participants," by Julius M. Kernbach et al.
MEDIA CONTACT: Danilo Bzdok, RWTH Aachen University, GERMANY; e-mail: < danilo.bzdok@rwth-aachen.de >
Proceedings of the National Academy of Sciences