The factors which were predictive of risk and used in the model were older maternal age, smaller height, male sex of baby, labour induced by prostaglandin, not having had a previous vaginal birth, and later birth.
Women at low predicted risk of emergency caesarean section were also at low risk of the most dangerous complication of attempting vaginal birth, a ruptured uterus.
Rates of caesarean section are rising worldwide. A major cause of this is that fewer women are attempting vaginal birth after caesarean section due to concerns regarding safety. This new method may provide a way of predicting those women who can safely attempt a vaginal birth after a previous caesarean section.
Citation: Smith CL, Anthony S, Hubank M, Leiper JM, Vallance P (2005) Effects of ADMA upon gene expression: An insight into the pathophysiological significance of raised plasma ADMA. PLoS Med 2(10): e264.
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