Researchers report the development of an ionic liquid-based oral insulin formulation that remains stable for prolonged periods at room temperature and under refrigeration; administration of low insulin doses to rats significantly decreased blood glucose levels for up to 12 hours, and oral delivery of insulin doses resulted in up to 45% decrease in blood glucose levels in rats, offering a potential alternative to injectable insulin deliveries for diabetic patients.
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Article #17-22338: "Ionic liquids for oral insulin delivery," by Amrita Banerjee et al.
MEDIA CONTACT: Samir Mitragotri, Harvard University, Cambridge, MA; e-mail: mitragotri@seas.harvard.edu
Proceedings of the National Academy of Sciences