About The Study: Among critically ill adults receiving invasive mechanical ventilation, early use of an automated closed-loop ventilation system did not increase ventilator-free days at day 28 compared with protocolized conventional ventilation.
Corresponding Author: To contact the corresponding author, Jante S. Sinnige, MD, email j.s.sinnige@amsterdamumc.nl .
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(doi:10.1001/jama.2025.24384)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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