A leading expert in the health impacts of plastic pollution and microplastics is calling on the UN to end the use of toxic chemicals in all plastics, cap and reduce plastic production and argues against a treaty focused on waste management and recycling, as part of an international Plastics Treaty.
The World Health Organization (WHO) estimates that approximately one quarter of all global deaths are attributable to environmental harm including chemicals, pollution and waste.
Much of this pollution is linked to plastic production, use and disposal, and disproportionately affects low- and middle-income countries. Alarmingly, plastic production, is predicted to grow 300 percent by 2060 .
Dr Nicholas Chartres , Senior Research Fellow in the University of Sydney School of Pharmacy , has joined with other leading health experts, authoring an editorial for the WHO which outlines eight considerations the United Nations Environment Programme should consider when its members meet in August to discuss an international, legally-binding treaty to end plastic pollution.
“Plastics are a health hazard around the globe, affecting numerous bodily systems and increasing rates of chronic diseases, cancers, and infertility,” says Dr Chartres.
“The United Nations Environment Assembly resolved in March 2022 to negotiate a plastics treaty that would obligate member states to end plastic production because of its danger to human health,” Dr Chartres said.
“Yet, despite the importance of health in driving efforts to manage plastics pollution, the current proposed treaty text has major gaps that put human health at risk from hazardous chemicals and plastics.”
Dr Chartres and his co-authors argue the treaty needs to:
Microplastics and forever chemicals
“Plastics are made of more than 16,000 chemicals, mostly derived from oil and gas. Over 4200 are known to be hazardous , while the toxicity of the majority of the remaining is unknown,” said Dr Chartres.
This includes per- and poly fluoroalkyl substances (known as ‘forever chemicals’), phthalates and bisphenols (the ‘ everywhere and everyone chemicals ’), and other endocrine disrupting chemicals, which can interfere with our bodies’ natural hormone systems and lead to harmful health effects. Exposure to these and many other chemicals used in plastics has been identified to increase rates of chronic disease, including cancer, neurodevelopmental harm and infertility.
The authors also note the growing evidence that microplastics increase the risk of respiratory, reproductive and gastrointestinal harm , and have been linked to some forms of cancer based on their world-first review led by Dr Chartres.
Meanwhile, the healthcare industry has become increasingly reliant on single-use plastics, especially following the COVID-19 pandemic.
“Much of this plastic has gone to waste with little evidence of benefit from the shift. A plastics treaty should incentivise the health sector to promote environmental sustainability and innovations for safer materials.”
Bulletin of the World Health Organization
Commentary/editorial
Not applicable
Negotiating the plastics treaty to protect health and the environment
1-Jul-2025
The authors declare no conflicts of interest.