Rudolph's application of physiology to congenital heart disease significantly advanced understanding of normal and abnormal heart development in newborn humans. His research led to the development of new diagnostic and treatment methods for congenital heart defects.
A new study found that residential dust control measures are not effective in reducing blood lead levels in children. Despite parents' best efforts, lead contamination remains a significant concern, and experts call for stricter housing standards to protect children.
Researchers at the University of Pittsburgh found that HbA1 levels predict mortality from coronary artery disease in women with Type 1 diabetes. However, this association was not seen in men with the same condition. The study analyzed data from over 600 subjects and suggests a gender-specific link between hyperglycemia and CAD risk.
A recent study by Wake Forest University Baptist Medical Center found that middle school-aged adolescents who begin smoking cigarettes at age 11 or younger engage in twice the number of risky behaviors that could end their life. These risk behaviors include substance abuse, violence, and suicidal thoughts.
Research suggests that infrared thermometers can accurately measure newborn temperatures, especially after feeding and before transferring to cribs. However, using these devices on older infants may not yield accurate results.
Researchers found that 82% of mothers of full-term babies thought their child's temperament was easy, while only 34% of preterm baby mothers shared the same sentiment. This disparity may be attributed to prolonged hospital stays and limited social interaction with other mothers.
A study found that pain killers with ketamine and midazolam were safer and less likely to cause breathing issues than fentanyl/midazolam. The regimen prevented patients from remembering painful procedures and reduced parental ratings of pain and anxiety.
A recent study found that 5% of North Carolina middle school boys carried guns, while 20.2% carried clubs or knives, with both linked to substance use and violence. The study suggests that similar prevention programs should be introduced in elementary schools, along with substance use prevention.
A team of scientists has discovered a genetic mechanism controlling the inner workings of the biological clock, which also drives bodily rhythms such as temperature, blood pressure, hormones, and sleep-wake cycles. The findings may lead to more efficacious treatments for diseases like heart attacks and asthma.
Researchers found that otitis media with effusion decreases steadily in children between ages 2 and 5, with only a small percentage continuing to experience persistent fluid buildup after age 2.
Researchers at Harvard Medical School have made a groundbreaking discovery that suggests the brain's development may rely on a DNA cutting and pasting process. The study, led by Fred Alt, found that specific proteins involved in recombination are also crucial during brain development, leading to cell death in mice with genetic mutations.
A team of UI researchers has found a way to permanently deliver therapeutic genes to the lungs of patients with cystic fibrosis. The method uses a retrovirus that integrates into host DNA, allowing the gene to be reproduced in cells. This could lead to a permanent cure for CF and other genetic lung diseases.
The number of newborns infected with HIV has decreased significantly thanks to optimal anti-retroviral treatment for mothers, while the number of surviving HIV-infected children has risen. Early aggressive therapy, teamwork, and a holistic approach are key to keeping children well with HIV.
Research suggests that anesthesia during labor and delivery may cause temporary delays in nursing, but has no long-term effects. Breastfeeding is strongly recommended by the AAP, with newborns being nursed frequently to promote immune system development.
Expert Bruce P. Lanphear argues that federal standards ignore existing scientific evidence and fail to protect inner-city children from lead poisoning. He proposes a primary prevention approach, focusing on eliminating residential lead hazards before exposure, to mitigate the harmful effects of low-level lead exposure.
A UNC-CH study reveals that premature infants are resuscitated primarily based on parents' preferences and medical uncertainty, rather than solely on the prognosis of survival. The study found that resuscitation generally postpones death by only a few days but does not contribute substantially to over-treatment.
A comprehensive study of 195 short children found a strong link between shortness and behavioral adjustment problems. Growth hormone treatments improved behavior scores and conduct in many cases, with significant improvements in anxiety, depression, and attention deficit disorders.
A study by pediatricians from Wake Forest University found that gay teenage boys with multiple male partners are more likely to experience violence, drug abuse, and absence from school. The researchers suggest that clinicians can apply these findings to provide targeted support for these adolescents.
The UT Southwestern pediatric laboratory now has a Time-of-Flight mass spectrometer, allowing for local analysis of chemotherapeutic drugs and other substances. This technology aids in identifying molecular minutiae, potentially resolving side effects such as fatigue and cognitive problems associated with chemotherapy.
A study challenges the widely accepted pediatric practice of prescribing a 10-day course of antibiotics for uncomplicated ear infections, suggesting that five days of short-acting oral antibiotics are equally effective. The researchers found no significant difference in treatment failure rates when comparing the two treatment courses.
Researchers found that bone marrow transplant significantly improves disease-free survival for children with high-risk neuroblastoma. Additionally, follow-up therapy with high doses of retinoic acid shows promising results, with a three-year event-free survival rate of 55% compared to 16% for those treated with consolidation chemothera...
A study found that teenagers who identify as gay, lesbian or bisexual are more likely to report engaging in multiple risky behaviors and starting them at an earlier age. These teens also experience higher rates of emotional distress, including missed school due to fear and physical threats.
Researchers confirm that premature and low-birth weight infants should receive their immunizations at the same ages recommended for healthy, full-term babies. The study found that even the least immunologically mature preterm infants had adequate immune responses that lasted until age three to four.
Primary care physicians are spending more time with their young patients, providing increased preventive services and counseling. The study also found a rise in medication prescriptions, including antibiotics and the stimulant Ritalin, without clear evidence of their appropriateness.
A new study by Ohio State University researchers found a significant surge in trampoline-related injuries among children, with almost 250,000 treated between 1990 and 1995. The annual number of injuries grew from 29,600 to 58,400 per year during this period, with younger children most often suffering fractures or dislocations.
A Dartmouth Medical School study found that low asthma hospitalization rates in New Hampshire and Vermont were encouraging news for children and their families. The study suggests that regional trends do not always parallel national trends, highlighting the importance of considering population differences and healthcare system characte...
A recent study found that premature infants with bronchopulmonary dysplasia (BPD) are at a higher risk of cognitive and motor development problems. By 3 years of age, about 21% of BPD patients showed signs of retardation compared to less than 10% without the condition.
Researchers at UT Southwestern Medical Center have found a promising new treatment for meningococcemia, a deadly disease that affects children. The study, led by Dr. Brett Giroir, used bactericidal permeability-increasing protein (BPI) to treat severe cases of the disease and showed encouraging results.
Researchers found that colicky infants are more anxious and have more conflict in the first year after birth, but by three years old they are no different from other families. The "mood" of the family also improves over time.
A recent study found that children whose parents are obese have a significantly higher chance of becoming obese adults. The research examined over 800 young adults and showed that having an obese parent more than doubles the risk of obesity, while having normal-weight parents reduces the risk.
A new study found that 69% of babywalker-related injuries occurred in spite of adult supervision. Infant mobility is too great for young children to control, increasing the risk of falls and injuries. Researchers advocate for stricter standards on babywalker design to prevent further accidents.
Researchers at University at Buffalo and Roswell Park Cancer Institute found no link between chemotherapy use and cancer risk in children's offspring. The study analyzed health records of 153 children born to 91 chemotherapy patients, showing none developed cancer.
Researchers found that rush immunotherapy targeting a single allergen makes distinct changes in T cells and prevents allergic reactions. The study showed that T cells produce more interferon gamma, an element that lowers allergic responses, and shut off production of pro-allergic cytokines.
A new American Academy of Pediatrics study reveals that girls in the US are entering puberty earlier than previously thought, with black girls beginning around age 9 and white girls at 10. By their ninth birthday, 48% of black girls and 15% of white girls have begun breast or secondary hair development.
Researchers found that black children are nearly 2.5 times more likely than white children to receive hemodialysis versus peritoneal dialysis. The disparity was observed across different age groups, with younger black children being most likely to opt for hemodialysis.
A large-scale study found that infant screening for neuroblastoma fails to detect the most severe form of the disease in nearly 500,000 Canadian infants. The researchers conclude that some cases of neuroblastoma detected by screening may resolve spontaneously or fail to progress.
A new study reveals that media reports of vaccine injuries can cause fear, lead to costly litigation, and prevent infants from being immunized. The authors urge journalists to report on rare adverse events without distorting the facts, highlighting the importance of accurate information in protecting public health.
A five-center trial shows partial liquid ventilation is safe and effective, improving lung function and increasing survival chances for critically ill premature infants. The procedure involves introducing oxygen-rich liquid into the lungs, reducing pressure damage and improving oxygen exchange.
Newborns exposed to crack cocaine in the womb display excitability, lethargy, stress, and delayed motor skills, but may not require special care. Cocaine exposure may also impact parenting styles and lead to negative outcomes for babies.
A new study found that children living in communities with stricter fireworks laws are 7 times less likely to be injured than those in lenient areas. The study, published in Pediatrics, also recommends a nationwide ban on personal firework use except for licensed public displays.