Research by Paul L. Dunham and his team at Missouri State University found that REM sleep deprivation increases expression of proteins p38, PKA, and P2X3, known for initiating and sustaining chronic pain in migraines.
Researchers found chronic migraine sufferers experience higher levels of stigma, negatively impacting quality of life. The study, conducted by Dr. Jung E. Park and her team, used the Stigma Scale for Chronic Illness to assess stigma in outpatients with chronic and episodic migraines.
A study of over 1,300 migraine patients found a link between childhood abuse and an increased risk of stroke, transient ischemic attack, and myocardial infarction. The research suggests that early adverse experiences may influence cardiovascular health in adulthood.
A study of 17,337 adult members found a graded relationship between the number of adverse childhood experiences and the likelihood of experiencing frequent headaches. The researchers suggest that ACEs may contribute to the development and frequency of severe headaches later in life.
A study by the American Headache Society found that soldiers with post-traumatic headache and migraine reported improved sleep quality after three months of treatment. The research aimed to determine if effective headache treatment could also improve sleep quality among patients with these conditions.
Research reveals increased network activity and altered functional connectivity in multiple networks, reflecting the migrainous phenotype. This suggests that migraine is a disorder of the brain, with abnormalities present even outside of attacks.