Dompe farmaceutici SpA

A new analysis of the literature on NETosis from Dompé farmaceutici puts a spotlight on neutrophils in carcinogenesis and highlights the importance of targeting IL-8 and EVs in drug-resistant tumors

A new analysis of NETosis from Dompé farmaceutici puts a spotlight on neutrophils in carcinogenesis. Neutrophils' behavior is modulated by extracellular vesicles and interleukin-8, leading to tumor progression and drug resistance. Targeting IL-8 and EVs may lead to novel drugs to regulate neutrophil biology.

SourceDompe farmaceutici SpA·JournalFrontiers in Oncology·DateFeb 1, 2023

New published data point to spike protein interactions with estrogen receptors as a cause for coagulopathy in COVID-19 patients, signaling sex effects and a path to improved vaccines

Researchers discovered a novel interaction between the SARS-CoV-2 Spike protein and human Estrogen Receptor Alpha, which may contribute to severe coagulopathy in COVID-19 patients. The study suggests that modulating ER signaling could mitigate rare vaccine side effects.

SourceDompe farmaceutici SpA·JournalScience Advances·TypeExperimental study·DateNov 30, 2022