Researchers have discovered biomarkers for ALS in cerebrospinal fluid, which could enable rapid diagnosis and prompt treatment. These biomarkers have high sensitivity and specificity, and may be used to monitor drug effectiveness in clinical trials.
Recent studies investigate the toxic potential of ultrafine and fine particles, finding worsening health outcomes for people with chronic heart and lung disease. Exposure to small particles also contributes to increased risk of emergency visits, hospitalizations, and death.
A study found that increasing Vitamin B-6 intake rapidly improved its status and decreased DNA strand breaks in both smokers and non-smokers. The researchers also suggested that Vitamin B-6 has a high prevalence of inadequate dietary intake in the general population, particularly among smokers.
Researchers have discovered that adult hearts contain stem cells capable of regenerating muscle tissue lost due to disease or wear. These findings open the possibility for the development of restorative therapies following heart attacks and other cardiovascular diseases.
A recent study found that adolescent girls who consumed more calcium on average weighed less than those who consumed less calcium. The researchers discovered that an increase in one serving of dairy products or supplements resulted in a significant reduction in weight and body fat.
Researchers have discovered that cholestyramine can reduce the toxic effects of brevetoxin, a neurotoxin produced by harmful algal blooms. This finding has implications for the treatment of ciguatera fish poisoning, a chronic disease affecting millions worldwide.
Prolactin's role in breast cancer has been redefined with the discovery of its ability to travel directly into cell DNA. This finding suggests a new paradigm for hormone function and offers potential therapies for blocking tumor growth.
Researchers have identified a group of cells in the spinal cord that control ejaculation, which can be manipulated to treat sexual dysfunction. The discovery has implications for paraplegic men and those experiencing ejaculatory problems.
Researchers used genetically modified mice to understand cocaine's brain mechanisms, revealing the drug's actions go beyond dopamine and norepinephrine transporters. The findings suggest the serotonin system may also be a target for cocaine treatment.
Dr. Sundquist's research has identified key cellular proteins necessary for HIV release, providing potential new targets for anti-HIV drugs. By altering the structure of these proteins or blocking their interaction with HIV, future treatments may slow or halt infection.
A study found that prenatal exposure to nicotine increases the function and density of GABAa receptors in brain regions controlling breathing, leading to more frequent and prolonged episodes of apnea in newborn rats. This suggests a possible link between maternal smoking during pregnancy and increased risk of Sudden Infant Death Syndro...
Research suggests that a moderate caloric restriction diet rich in fruits and vegetables can lower cancer risk in mice by 60% compared to those with high fat diets. Exercise also showed a modest effect on polyp numbers, but with limited statistical significance.
Research by Dr. Patricia Molina's team found that alcohol intoxication severely impairs the brain's ability to restore normal blood pressure after a small blood loss, leading to delayed recovery and increased risk of infection in trauma patients. This finding has significant implications for treating intoxicated trauma victims.
Researchers believe olfactory ensheathing cells from the nose hold potential to repair spinal cord injuries. These cells can be obtained from adult donors and offer a possible auto-transplantation method, resolving tissue availability issues.
A new study found that walking at moderate pace for 40 minutes a day can restore elasticity of carotid artery in postmenopausal women by 48%. This benefit may explain the positive impact of regular aerobic exercise on cardiovascular health.
Researchers found that high protein diets led to decreased hydration levels and abnormal kidney function tests. The study suggests that athletes and non-athletes alike should increase fluid intake when consuming high protein diets.
Research suggests that defects in 'orphan' inositol polyphosphates may contribute to diseases such as manic depression and cancer. Dr. York's work identifies biological roles for these molecules and provides a basis for designing more specific drugs with fewer side effects.
Researchers are working on developing new treatments for bioterrorism and drug resistance, including the use of bacteriophages to target specific bacteria. Understanding how microbes create biofilms is also crucial in preventing chronic infections.
Researchers found nicotine shows promise as an antidepressant in a Wistar-Kyoto rat model of depression. The study suggests that nicotine or nicotinic agonists could be therapeutic options for treating depressive illnesses. However, the risks associated with cigarette smoking outweigh any potential benefits.
Researchers found that lipitor prevented both acute and relapsing forms of multiple sclerosis-like disease in mice, reversing symptoms in those with chronic relapsing form. Lipitor also reduced CNS inflammation by inducing anti-inflammatory cytokines and suppressing pro-inflammatory cytokines.