Researchers developed a nasal spray vaccine that shifts the immune response toward peanut tolerance in mice with established allergies. The vaccine's nano-emulsion adjuvant promotes a strong infection-fighting response that suppresses allergic reactions.
Research found that a protein interacts with blood vessels to intensify anaphylaxis symptoms, making it a potential target for drug therapies. Therapies targeting this protein could moderate reactions and make anaphylaxis less deadly.
Research published in the Journal of Experimental Medicine found that a mother's diet can protect nursing newborns against food allergies. The study, supported by Food Allergy Research & Education (FARE), suggests that mothers should feel free to eat a healthy and diverse diet throughout pregnancy and breastfeeding.
FARE has awarded over $1 million to three scientists to study the causes of food allergies and develop new treatments. The recipients will focus on improving oral immunotherapy, IgE glycosylation, and understanding the role of Dock8 in maintaining tolerance to food antigens.
The FARE Investigator in Food Allergy Awards support early and mid-career researchers expanding scientific understanding of food allergy through education and basic and clinical research. Recipients include Jessica O'Konek and Duane Wesemann, who will investigate nanoemulsion-based vaccines and the influence of microbial exposures on p...