Fudan University Institute of Science and Technology

Seeing tumor boundaries in 3D within 30 minutes: Cell study develops a new intraoperative imaging platform for glioma infiltration

A new intraoperative imaging platform called ULTRA combines rapid tissue clearing, stimulated Raman scattering microscopy, and AI-based virtual staining to perform deep 3D histological imaging. This enables the visualization of key histological features across different glioma subtypes and facilitates glioma margin analysis.