Researchers predict a low risk of dengue infection among foreign visitors to the Rio Olympics, with estimates suggesting as few as three symptomatic cases and potentially no asymptomatic infections at all. The predictions are based on sophisticated mathematical modeling techniques and data from Brazil's Health Ministry.
Researchers have developed a single-layer organic nanometer-scale transistor that can detect molecules associated with neurodegenerative diseases and some types of cancer. The device uses glutathione and glutathione S-transferase to identify target molecules, offering sensitivity and potential for rapid diagnosis.
A study by researchers at the Heart Failure Center of the University of São Paulo suggests that wearing a respirator mask can lessen the impact of vehicle emissions on people with heart failure. The results also indicate that this type of mask can reduce the risk of developing cardiovascular disease for healthy individuals.
Researchers found that neural circuits in the striatum, a subcortical part of the forebrain, are involved in both pleasure and caloric value perception. The brain prioritizes energy storage over palatability, suggesting a link between sweetness and calorie craving.
Researchers identified new glioma subtypes by analyzing DNA methylation profiles in 1,122 adult glioma samples. These subtypes can help stratify patients more accurately and improve treatment protocols, with some subgroups displaying similarities to pilocytic astrocytomas and better patient survival.
Research finds that elevated CO2 reduces stomatal conductance, increasing water use efficiency and delaying physiological responses to drought. This study provides new insights into the genetic mechanisms underlying sorghum's resilience to climate change.
Researchers have identified the Jagged1 gene as a potential target for therapies to combat Duchenne muscular dystrophy, a genetic disorder characterized by progressive muscle degeneration. Increasing expression of JAG1 was shown to prevent the development of degenerative disease in zebrafish models.
A study found that reducing Amazon deforestation leads to improved air quality and a decrease in premature deaths from exposure to particulate matter. The research estimated that the 40% reduction in Brazilian deforestation between 2001-12 prevented approximately 1,700 adult deaths annually in South America.
The ALICE experiment confirms a fundamental symmetry between nuclei and antinuclei in terms of charge, parity and time. The measurements were made possible by the ALICE experiment's high-precision tracking and identification capabilities.
A Brazilian antibody developed by Recepta Biopharma with FAPESP support will be used to create a new cancer drug. The technology has been licensed to US-based company Mersana Therapeutics, which will use it to develop an immunoconjugate against target tumor cells.
Agrindus and Nanox developed a technology that extends the shelf life of grade A pasteurized whole milk from seven to 15 days by incorporating silver-based microparticles into rigid plastic bottles. This innovation doubles the shelf life, benefiting logistics, storage, quality, and food safety.
A new nanobiosensor can detect biomarkers for multiple sclerosis and other nervous system diseases. By analyzing the interaction between a patient's cerebrospinal fluid and the device, doctors can rule out or confirm diagnoses with greater confidence.
The new report provides a comprehensive analysis of the current bioenergy landscape, technology, production financing systems, and markets. It highlights opportunities for enhancing energy security and mitigating climate change through advanced biomass conversion technologies.
Brazilian researchers have discovered five new species of marine invertebrates, the ascidians, which are rich in natural compounds with potential uses in medicine. The newly found species contain substances that can eliminate cancer cells but also destroy healthy cells.
Researchers discovered a new mechanism to inhibit proteasomes, a target for cancer therapy, paving the way for more effective and less toxic chemotherapy drugs. A series of molecules based on this mechanism have been developed, and their potential is being tested.
Researchers at University of São Paulo identified INXS RNA, which modulates BCL-X gene and induces programmed cell death. Local injections of plasmid containing INXS reduced subcutaneous malignant tumors by 10-fold in mice.
A 2°C rise in temperature could improve photosynthesis and antioxidant protection in plants like Stylosanthes capitata Vogel. Leaf area index increased by 32%, aboveground biomass production by 16%.
A study found that logging, partial destruction by burning, and fragmentation result in the loss of nearly 54 million tons of carbon annually, equivalent to up to 40% of total deforestation. This degradation has a severe impact on the forest, with enormous quantities of stored carbon being lost into the atmosphere.
Researchers estimate that the reduction of soil carbon stock caused by converting pasture areas to sugarcane plantations can be offset within two or three years. The study found that the introduction of sugarcane to pasture areas can compensate for or even add to the initial soil carbon stock, depending on management practices.
Researchers confirm the role of Phox2b-expressing neurons in detecting and modulating CO2 levels. The study reveals a small region of the brain maintains homeostasis by detecting adequate CO2 levels, which may help prevent sudden death cases.
The SPRINT program aims to advance scientific research through partnerships between researchers from institutions in Brazil and abroad. FAPESP will provide funding for travel, health insurance, and living allowances for participating researchers.
FAPESP has invested $680 million in 17 Research, Innovation and Dissemination Centers (RIDCs) in São Paulo, Brazil, with a focus on various research areas. The centers aim to contribute to commercially relevant high-impact applications while disseminating knowledge through education.
The ICTP South American Institute for Fundamental Research (ICTP-SAIFR) will focus on areas like gravitation, particle physics, and field theory. The center will host visiting researchers, organize schools and workshops for PhD students, and hire permanent professors to promote scientific excellence in South America.